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ISTH 2021 Congress

July 17-21, 2021. Philadelphia, PA.

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  • Abstract Number: PB1261

    Tailored Anticoagulant Treatment after a First Venous Thromboembolism: Protocol of the Leiden Thrombosis Recurrence Risk Prevention (L-TRRiP) Study, a Cohort Based Randomized Controlled Trial

    J.L.I. Burggraaf1, N. van Rein1, R.H.H. Bemelmans2, S. Benimadho3, J.W.K. van den Berg4, M. Coppens5, A. Dees6, L.M. Faber7, W.K. de Jong8, T. Koster9, A.T.A. Mairuhu10, K. Meijer11, M. Nijkeuter12, M.E. van den Akker - van Marle13, S. le Cessie13,1, M.V. Huisman14, F.A. Klok14, S.C. Cannegieter1,14, L-TRRiP study investigators

  • Abstract Number: PB0676

    Tailoring the Effect of Antithrombin-targeting Therapy in Hemophilia A Using in Silico Thrombin Generation

    R. de Laat-Kremers1, M. Ninivaggi1, I. van Moort2, M. de Maat2, B. de Laat1

  • Abstract Number: PB0656

    Targeted CRISPR/Cas9-mediated Gene Addition to a Safe Harbor in Placental Cells for the Treatment of Hemophilia A

    R.M. Ramamurthy1, M. Rodriguez1, D. Meares2, A. Farland2, A. Atala1, C.B. Doering3, H.T. Spencer3, C.D. Porada1, G. Almeida-Porada1

  • Abstract Number: PB0869

    Targeted Next Generation Sequencing for the Diagnosis of Patients with Inherited Thrombocytopenias

    O. Gilad1, O. Steinberg - Shemer1, O. Dgany2, T. Krasnov2, S. Noy - Lotan2, J. Yacobovich1, H. Tamary2,1

  • Abstract Number: PB1032

    Targeted Proteasomal Degradation of Platelet BTK and TEC as a Novel Approach in Thrombosis Prevention

    A. Munkacsi1, K. Sledz1, I. Hers1

  • Abstract Number: OC 36.4

    Targeted Protein Biomarker Discovery to Predict Cardiovascular Outcome in Peripheral Artery Disease

    B. Kremers1, J. Posma1, S. Heitmeier2, H. ten Cate1,3, A. ten Cate-Hoek1,3, R. van Oerle1, J.-W. Daemen3, B. Mees3, H. Spronk1

  • Abstract Number: OC 60.3

    Targeting Coagulation Factor Xa and IIa Differentially Regulate Inflammation

    K. Shahzad1, I. Gadi1, S. Fatima1, A. Elwakiel1, B. Isermann1

  • Abstract Number: PB1037

    Targeting Pathways of Mitochondrial Neutrophil Extracellular Trap Formation to Inhibit Progression of Abdominal Aortic Aneurysms in Preclinical Models

    S. Bleichert1, N. Ibrahim1, J. Klopf1, V. Knöbl1, A. Busch2, M. Bailey3, W. Eilenberg1, C. Neumayer1, C. Brostjan1

  • Abstract Number: PB0148

    Targeting Thymidine Phosphorylase May Be a Novel Therapy for COVID-19

    H. Yue1, K. Denning1, W. Li1

  • Abstract Number: PB0199

    TEG/ROTEM: A Tool to Aid in the Diagnosis and Management of COVID 19 Coagulopathies – A Systematic Review

    S. Kazi1, A. Noureldin2, K. Fainchtein2, Y. Deng2, M. Othman2,3

  • Abstract Number: PB0597

    Telemedicine in Hemophilia: A Comprehensive Review

    C.L Li1, K. Strike2,3, D. Matino2,4, M. Bhatt1,2, K. Decker2, A.K. Chan1,2

  • Abstract Number: LPB0083

    Temporal Assessment of Platelet Proteome and fFnction during ex vivo Anticoagulation

    S. Tassi Yunga1, A. Gowers1, A. Melrose1, M. Fitzgerald1, A. Rajendran1, A. Reddy1, P. Wilmarth1, L. David1, O. McCarty1, J. Aslan1

  • Abstract Number: PO159

    Tetralogy of Fallot with Thrombolytic Ongoing Processes: A Case Report

    B. Badlou1, H. Najafpour2.

  • Abstract Number: OC 58.1

    The “Double-edged Sword”: The Role of LMWPTP in Platelet Hyperactivity in Cancer Patients

    A.V.S. Faria1,2, B. Yu2, S.S. Andrade3, M. Peppelenbosch2, G. Fuhler2, C.V. Ferreira-Halder1

  • Abstract Number: PB1278

    The Accelerated Regimen of Low Dose Recombinant Tissue-type Plasminogen for the Treatment of Acute Pulmonary Embolism: A Case Series from Vietnam

    B.H. Hoang1, G.P. Do2, D.L. Le3, T.H.T. Bui4, N.T. Bui5, M.Q. Nguyen3, D.A. Nguyen4, M.M Dinh6, L.H. Nguyen1

  • Abstract Number: PB0875

    The Analysis of Platelet Functional Activity in Patients with Thrombocytopenia

    M. Reshetova1, A. Poletaev1, E. Seregina1,2, D. Polokhov1

  • Abstract Number: PB0293

    The Assessment of Thrombotic Complication in Patients with COVID-19

    V.M. Popov1, M. ANDREESCU1, M. OMER1, M. Popescu1, C. Despan1, L. Iliescu1, C. Pirvu1, A. Grigorie1, M. Niculae1, O. Constantin1, A. Rus1, A. Badea1, I. Simion1, M.I. Balea1

  • Abstract Number: PB1126

    The Association among von Willebrand Factor, ADAMTS-13, D-dimer, and Soluble P-selectin with Venous Thromboembolism Incidence in Cancer Patients: Systematic Review and Meta-analysis

    B.P. Putra1, F.N. Putra2

  • Abstract Number: LPB0117

    The Association of Emicizumab and rFVIIa for Major Orthopaedic Surgery

    C. Carulli1, S. Linari2, L. Pieri2, G. Castaman2

  • Abstract Number: PB0794

    The Bacteria-associated Thrombosis, Thrombophlebitis and LEmierre Syndrome (BATTLE) Registry: Background and Rationale

    L. Valerio1, G. Corsi2, T. Sebastian3, S. Barco3

  • Abstract Number: PO142

    The Case of Acquired Haemophilia A

    O. Stasyshyn1, V. Krasivska1

  • Abstract Number: PO191

    The Case of Obstetric APS – A Therapeutic Challenge

    J. Teliga-Czajkowska1, K. Czajkowski2, A. Sikorska3

  • Abstract Number: PB0229

    The Characteristics and Outcomes of Critically Ill Patients with COVID-19 who Received Systemic Thrombolysis for Presumed Pulmonary Embolism: An Observational Study

    M. So1, D. Steiger1, M. Takahashi1, N. Egorova2, T. Kuno1.

  • Abstract Number: PB0548

    The Clinical Bleeding Phenotype of Patients with Non-severe Hemophilia A and B

    A. Zwagemaker1, F. Kloosterman1, M. Coppens2, C.N. Bagot3, E.A.M. Beckers4, S. Boyce5, P. Brons6, M.H. Cnossen7, J. Eikenboom8, F.W.G. Leebeek9, C. Male10, K. Meijer11, L. Nieuwenhuizen12, S.C. Gouw1,13, J.G. van der Bom14, G. Castaman15, K. Fijnvandraat1,16, DYNAMO Study Group

  • Abstract Number: PB0843

    The Clinical Burden of Congenital and Immune-mediated Thrombotic Thrombocytopenic Purpura: A Retrospective Cohort Analysis

    A. Satija1, S. Tzivelekis2, E. Swallow1, O. Patterson-Lomba1, A. Briggs1, E. Yim1, B. Mellgard3

  • Abstract Number: PB0013

    The Coagulation and Fibrinolisys Changes Undergoing the Ramipril and Losartan Treatment of Concomitant Arterial Hypertension and Diabetes Mellitus Type 2

    E. Shorikov1, D. Shorikova1, P. Shorikov1, O. Khukhlina1

  • Abstract Number: PB0065

    The Coagulation Balance: Intracranial Hemorrhage in a Patient with Antithrombin Deficiency. A Case Report

    I. Machado1, S. Teixeira1, D. Cibele Gonçalves1, C. Monteiro1, M. Carvalho1, L. Ricca Gonçalves1, C. Neves1, M.d.C. Koch1

  • Abstract Number: PB0240

    The Comparison of Different Coagulation Markers in Thrombosis Prediction in COVID-19 Pneumonia

    M. Krykhtina1, K. Bielosludtseva1, T. Pertseva1, L. Konopkina1

  • Abstract Number: PB0285

    The Comparison of ISTH Criteria for Disseminated Intravascular Coagulation (DIC) Scale, Padua Scale, D-dimer and Fibrinogen Like the Best Predictor of Thrombosis in COVID-19 Pneumonia

    K. Bielosludtseva1, T. Pertseva1, L. Konopkina1, M. Krykhtina1

  • Abstract Number: PB0866

    The Copenhagen Founder Variant GP1BA c.58T>G is Causal of Monoallelic Bernard-Soulier Syndrome

    E. Leinøe1, N. Broens1, A.O. Rasmussen2, M. Gabrielaite2, S. Rosthoej3, E. Zetterberg4, S.R. Ostrowski5, M. Rossing2

  • Abstract Number: PB0814

    The Correlation of Vascular Platelet Hemostasis Disorders and Typical Autoantibodies in Hepatic Cirrhosis at the Outcome of Autoimmune Hepatitis in Children

    E. Konovalova1, A. Lavrova1, M. Presniakova1

  • Abstract Number: NUR 01.4

    The DATCH Project: Developmentally Appropriate Tools for Children with Hemophilia to Help Them Better Understand Their Disease

    C.L Li1, N. Seroski2, A. Sohanlal1,3, K. Strike4,5, R. Goldsmith5, K. Decker5, A.K. Chan1,2,5

  • Abstract Number: PO149

    The Detection of Hemophilia C in a 66-year-Old Patient with Postoperative Urinary Bleeding

    I. Melnichenko1,2, T. Arakelyan1, N. Sargsyan2,3, L. Sargsyan1,2, S. Danielyan4, G. Tamamyan1,2, H. Khachatryan2,3

  • Abstract Number: PB0558

    The Devil is in the Detail: An Irish Approach to Switching to Emicizumab Prophylaxis in an Adult Comprehensive Care Centre (CCC)

    E. Singleton1, N. Larkin1, M. Mc Gowan1, S. Roche1, C. Bergin1, M. Byrne1, K. Ryan1, M. Lavin1, J. O Donnell1, N. O Connell1

  • Abstract Number: PB1058

    The Diagnostic Utility of the Taipan Snake Venom Time in an Era of DOACstop™

    E. Foxton1, R. Polgrean1, M. Desborough2, G. Ling2

  • Abstract Number: OC 22.2

    The Difference in the Transglutaminase Activities of Proteolytically and Non-proteolytically Activated FXIII A is Dependent on the Substrates

    R. Darul Amne Syed Mohammed1, M. Maurer1

  • Abstract Number: PB0780

    The Distribution of Anti-platelet Membrane Glycoprotein Antibodies Subtypes in Children with Primary Immune Thrombocytopenia and its Relationship with Therapeutic Effect

    R. Li1, R. Yang1

  • Abstract Number: PB0297

    The Effect of Chronic Anticoagulation and Antiplatelets on COVID-19 Infection

    J. Kaur1, A. Abdou1, M. Mohammed1, Y. Nadeem1, M. Kulkarni1, P. Dixit1, Q. Jehangir1, A. Morani1, Y. Lee1, I. Mohamed1, M. Qamar1, P. Pulapati1, J. Duong1

  • Abstract Number: PB0277

    The Effect of Covid-19 Lockdown on Patients Taking Warfarin

    M. Roberts1

  • Abstract Number: PB0060

    The Effect of Dextran Sulfate in Heparin Monitoring Reagents

    E. Dean1

  • Abstract Number: PB1047

    The Effect of DNase I in Combination with Unfractionated Heparin or Low Molecular Weight Heparin in a Mouse Model of Sepsis

    S. Medeiros1, N. Sharma1, D. Dwivedi1, S. Sohrabipour1, V. De Sousa1, J. Zhou1, P.C Liaw1

  • Abstract Number: PB0333

    The Effect of DOAC StopTM on Measuring Antithrombin Activity

    K. Mayger1,2,3, N. De Jager1, E. Foxton1, A. Doyle2, B.J. Hunt2

  • Abstract Number: PB0413

    The Effect of Lower-leg Trauma and Knee Arthroscopy on the Natural Anticoagulant and Fibrinolytic Systems

    C. Touw1, B. Nemeth1, R. van Adrichem1, W. Lijfering1, A. van Hylckama Vlieg1, R. Nelissen1, T. Lisman2, S. Cannegieter1

  • Abstract Number: PB0053

    The Effect of Lower-leg Trauma and Knee Arthroscopy on Thrombin Generation

    C.E. Touw1, B. Nemeth1, R. van Adrichem1, W. Lijfering1, A. van Hylckama Vlieg1, R. Nelissen1, T. Lisman2, S. Cannegieter1

  • Abstract Number: OC 20.3

    The Effect of Platelets on Thrombin Generation in the Premature Infant: The EVENT Study

    C. Murphy1,2, E. Neary3,4, B. Kevane5, D. O'Reilly2, J. O'Loughlin6, A. EL-Khuffash2,1, P. Maguire7, F. NíAinle5,7,8,9, N. McCallion2,1

  • Abstract Number: PB1314

    The Effect of Prothrombin Complex Concentrate and Cryoprecipitate on the Frequency and Severity of Multiple Organ Dysfunction Syndrome in Massive Obstetric Haemorrhage

    V. Sedinkin1, O. Klygunenko1, O. Volkov1

  • Abstract Number: PB0674

    The Effect of rFVIIa and Mim8 Combination in Hemophilia A-like Blood

    M. Ezban1, K. Jensen1, J. Lund1

  • Abstract Number: PB0360

    The Effect of Trough Dabigatran Plasma Concentration on Rotational Thromboelastometry Parameters

    M. Milić1, J. Štanfel1, K. Paradinović1, V. Šerić1

  • Abstract Number: PB0295

    The Effects of COVID-19 Pandemic on Children with Haemophilia

    F.B. Kurtipek1, D. Gürlek Gökçebay1, V. Çulha1, N.Y. Özbek1

  • Abstract Number: PB1004

    The Effects of Iron Deficiency on Platelet Function, Indices, and Clinically Reported Hemostasis: A Prospective Clinical Study of Iron Deficient Women Receiving IV Iron

    B. Elstrott1, M. West2, H.H.S. Lakshmanan3, J. Aslan3, J.J. Shatzel2,3

  • Abstract Number: PB0520

    The Efficacy and Prognosticator for Inhibitor Eradication in Hemophilia A Boys with High-titer Inhibitors Using a Low-dose Immune Tolerance Induction Strategy (with or without Immunosuppressants): Data from the National Center for Children’s Health of China

    Z. Li1, Z. Chen1, G. Liu1, X. Cheng1, W. Yao1, K. Huang1, G. Li1, Y. Zhen1, X. Wu1, S. Cai1, M.-C. Poon2, R. Wu1

  • Abstract Number: PB1145

    The Evaluation of the Children with Intracranial Thrombosis

    A. Meral Güneş1, S. Güler1, Ö. Tüfekçi2, M. Sezgin Evim1, B. Baytan1, Ş. Yılmaz2, H. Ören2

  • Abstract Number: PB0445

    The Experience of Oran University Hospital in Algeria in the Management of Acquired Hemophilia

    R. Messaoudi1, D.SAIDI, N.LAHMAR, D.BELALDJ, A.MOUADEN, M.BENSAHLI, M.DJAAFR,H.TOUHAMI

  • Abstract Number: LPB0039

    The Extracellular Protease EpiP from S. aureus Triggers Blood Coagulation by Proteolytically Activating Prothrombin and Platelet Protease-Activated Receptor 1

    V. De Filippis1, I. Artusi1, G. Pontarollo2, L. Acquasaliente1, A. Pagotto1, C.M. Radu3, F. Bagnoli4, G. Pietrocola5, P. Speziale5

  • Abstract Number: OC 41.2

    The Factor XII-uPAR Axis Drives Ovarian Cancer Maintenance and Progression

    K.L. Bane1, J. McAnulty2, A. Gandhi2, S. Vatolin1, Y. Yang3, M.J. Flick3, A. DiFeo2,4,5, E.X. Stavrou1,6

  • Abstract Number: LPB0016

    The Fibrin(ogen) γ-chain Integrin αIIbβ3 Binding Motif is Dispensable for Platelet Accumulation but Modifies Cross-linking in the Injured Liver

    L.G. Poole1, D.J. Groeneveld1, H.M. Cline-Fedewa1, M.J. Flick2, J.P. Luyendyk1

  • Abstract Number: PB0588

    The FⅨ Gene Mutation Analysis of Hemophilia B in China Central and Western Regions

    W. Wang1, L. Xu2, J. Wu3, J. Jin4, J. Huang4, Q. Zhang5, M. Zhou5, Z. Xu6, Y. Huang6, J. Peng7, Q. Hu1

  • Abstract Number: PB0039

    The FV East Texas Variant Causes Bleeding in a Three Generation Family from Indiana

    J. Peterson1, S. Gupta2, N. Martinez1, A. Mast1

  • Abstract Number: PB0893

    The Glanzmann’s Thrombasthenia Registry (GTR): Safety of Platelet Therapy in Patients with Glanzmann’s Thrombasthenia, with a Focus on Changes in alloimmunization Status

    M.-C. Poon1,2, R. d’Oiron3, S. Baby4, R.B Zotz5,6, G. Di Minno7

  • Abstract Number: PB0340

    The Impact of Inactive FVIII Antigen in Factor VIII Deficient Plasma on the Measurement of FVIII Inhibitors

    A. Wood1, N. Kesavan1, A. Sadeghi-Khomami,1, K. Black1, M. Boylan1, R. Ni2, J. Della Maestra2, P. Erb2, D. Foulon2, H. Hoogendoorn2

  • Abstract Number: PB0056

    The Impact of Lower-leg Injury and Knee Arthroscopy on Procoagulant Factor Levels

    C.E. Touw1, B. Nemeth1, I. Schipper1, R. Nelissen1, S. Cannegieter1

  • Abstract Number: PB0554

    The Impact of PK-guided Prophylaxis on Clinical Outcomes and Resource Utilization in Hemophilia A Patients: Real-world Evidence From the CHESS II Study

    E. Ferri Grazzi1, T. Burke1,2, J. O'Hara1,2, S.X Sun3

  • Abstract Number: PB0651

    The Impact of Platelet αIIbβ3 on the Hemostatic Efficacy of Platelet-derived FVIII Gene Therapy

    H. Yu1,2, J.A. Schroeder1,2, J.G. Mattson2, Q. Shi1,2,3,4

  • Abstract Number: PB1078

    The Impact of Strong Inducers on Direct Oral Anticoagulant Plasma Levels: A Retrospective Study

    A.-L. Sennesael1, A.-S. Larock1, P. Hainaut2, S. Lessire3, M. Hardy3,4, J. Douxfils5, A. Spinewine1,6, F. Mullier4

  • Abstract Number: LPB0046

    The Impact of the ABO Blood Group on Postpartum Haemorrhage Risk among Women with Thrombocytopenia

    S. Arcudi1, A. Ronchi2, M. Capecchi3, M.W. Ossola2, I. Mancini1, A.M. Marconi4, G. Podda5, A. Artoni6

  • Abstract Number: PB0772

    The Importance of Follow up Post PE

    M. Roberts1

  • Abstract Number: PB0664

    The Importance of Patient Preferences and Other Patient-Centric Metrics in Developing and Evaluating New Haemophilia Treatments

    T. Burke1,2, S. Asghar1, J. O'Hara1,2, D. Yee3, S. Kar3

  • Abstract Number: OC 52.1

    The Importance of the GPIbα Intracellular Tail in VWF-mediated Platelet Signaling Events and Platelet/Neutrophil Interactions

    A. Adela Constantinescu-Bercu1, Y.A Wang1, K.J Woollard1, P. Mangin2, K. Vanhoorelbeke3, J.T. Crawley1, I.I Salles-Crawley1

  • Abstract Number: LPB0060

    The Incidence of Severe Infusion Reactions Associated with Common Iron Repletion Strategies

    A. Arastu1, J. Cohen2, M. Oakes1, S. Olson3, B. Elstrott1, J. Aslan4, T. DeLoughery3, J. Shatzel3

  • Abstract Number: PB1292

    The Influence of Thrombophilic Anamnesis and Thrombotic Complications Heredity

    N. Vorobyeva1,2, D. Gamyrkina2

  • Abstract Number: PB0768

    The Intact Heavy Chain of Plasminogen Supresses Angiogenesis More Strongly than the Known Angiostatin

    K. Gershkovich1, L. Mukhametova2, R. Aisina2

  • Abstract Number: OC 37.4

    The Intracellular Tail of GPIbα Augments GPVI-mediated Signaling in Mice

    A. Constantinescu-Bercu1, Y.A Wang1, K.J Woollard1, P. Mangin2, K. Vanhoorelbeke3, J.T. Crawley1, I.I Salles-Crawley1

  • Abstract Number: PB0167

    The Kallikrein-kinin System in Bronchoalveolar Lavage Fluid from Patients with COVID-19

    C.P. Martens1,2, P. Van Mol3,4, J. Wauters5,6, E. Wauters7, T. Gangnus8, B. Noppen9, L. Liesenborghs1,10, E. Heylen10, S. Jansen10, L.C. Velásquez Pereira1, M.M Engelen1,2, A. Van Herck7, R. Vos7,4, C. Vandenbriele1,2, K. Martinod1, B.B Burckhardt8, M. Vanhove9, P. Verhamme1,2, J. Neyts10, T. Vanassche1,2

  • Abstract Number: OC 12.1

    The Khorana Score Is a Marker of Poor Cancer Prognosis, Independent of Development of VTE

    G. Soff1, C. Sathe2, C. Poon1, S. Yin1, S. Devlin1,1, D. Sarasohn1, L. Gilbert1, A. Khorana3, S. Mantha1

  • Abstract Number: OC 68.3

    The Link between Inflammation, Coagulation and Endothelium Damage in COVID-19: Evidence from an Exploratory Cross-sectional Study

    M.R. Peralta1, V. Muczynski2, J. McVey3, B. Gration4, P. Lane1, L. Pagala1, A. Riddell1, S. Baghani5, B. Agarwal6, H. Avula7, K. Gomez1, A. Davenport8, A. Drebes1, S. Taybali4, K. Tushar9, D. Aggarwal4, C. Diaz Garcia1, A. Nair10, D. Martin11, P. Chowdary1

  • Abstract Number: LB 01.4

    The Management of SubSegmental Pulmonary Embolism without Anticoagulation

    G. Le Gal1, M. Kovacs2, F. Couturaud3, A. Hirsch4, M. Huisman5, E. Klok5, N. Kraaijpoel6, M. Righini7, M. Rodger4, P.-M. Roy8, O. Sanchez9, J. Schmidt10, S. Schulman11, S. Shivakumar12, A. Trinh-Duc13, U. Vinsonneau14, P. Wells1, C. Wu15, E. Yeo16, M. Carrier1

  • Abstract Number: PB0727

    The Paradoxal Association beetween Congenital FVII Deficiency and Thromboembolism

    I. krichen1, N. Moussa2, Y. Elloumi1, F. Megdich1, W. Fekih2, Y. Kammoun1, S. Kammoun2, C. Kallel1

  • Abstract Number: PB0575

    The Potential Benefits of Physical Exercises for Reducing Pain in Adult Haemophilic Arthropathy Patients: A Meta-analysis of Randomized Controlled Trials

    B.P. Putra1, F.N. Putra2

  • Abstract Number: LPB0085

    The Predominant Role of Arrestin3 in General GPCR Desensitization in Platelets

    P.K. Chaudhary1, S. Kim1, S. Kim1

  • Abstract Number: PB0327

    The Prevalence of Gene Polymorphism of the Cytochrome P-450 and VKORC1 System among the Indigenous Population of the Arctic

    N. Vorobyeva1,2, A. Vorobyeva2

  • Abstract Number: OC 71.3

    The Procoagulant and Fibrinolytic Balance of Microvesicles Predicts Mortality in Septic Shock Patients

    R. Lacroix1,2, C. Judicone3, K. Harti Souab2, A. Loundou4, T. Bouriche3, S. Cointe1,2, L. Vallier1, A. Bonifay1, E. Abdili2, L. Arnaud2, S. Robert1, P. Poncelet3, C. Grosdidier2, P. Morange1,2, J.-C. Gris5, J.-Y. Lefrant5, E. Cochery-Nouvellon5, M. Leone2, J. Albanese2, F. Dignat-George1,2

  • Abstract Number: OC 50.4

    The Prognostic Value of ADAMTS13 and von Willebrand Factor in COVID-19 Patients: A Prospective Study by Care Setting

    G.L. Tiscia1, G. Favuzzi1, A. De Laurenzo1, F. Cappucci1, L. Fischetti1, E. Chinni1, P. Vergura1, G. Miscio1, L. di Mauro1, D. Colaizzo1, E. Grandone1

  • Abstract Number: OC 23.3

    The Prognostic Value of Symptoms and Performance Status in Ambulatory Cancer Patients and Unsuspected Pulmonary Embolism: Analysis of an International, Prospective, Observational Cohort Study

    A. Maraveyas1,2, N. Kraaijpoel3, B. Georgios1, C. Huang2, I. Mahe4, L. Bertoletti5, A. Bartels-Rutten6, J. Beyer-Westendorf7, J. Constans8, D. Iosub9, F. Couturaud10, A. Munoz11, M. Biosca12, T. Lerede13, N. Van Es3, M. Di Nisio14

  • Abstract Number: PB0996

    The Proteasome Inhibitor, Bortezomib Induces Apoptosis and Activation in Gel Filtered Human Platelets

    H. Ghansah1, I. Beke Debreceni2, G. Szabó2, J. Kappelmayer2

  • Abstract Number: OC 19.3

    The R543L Protein Altering Variant in the FII Gene (F2) Is a Major Determinant of Coagulation Potential in Mexican Americans

    T. Howard1, M. Almeida1, V. Diego1, S. Jhaveri1, H. Nguyen1, J. Peralta1, J. Curran1, S. Kumar1, B. Luu2, J. Powell3, H. Meade4, R. Rajalingam5, M. Escobar6, D. Lehman7, R. DeFronzo7, L. Almasy8, S. Williams-Blangero1, R. Duggirala1, J. Blangero1

  • Abstract Number: PB0338

    The Red Blood Cell Paradox in Viscoelastic Coagulation Tests – Hemoglobin Concentration as a Confounder for Test Reliability?

    I. Pekrul1,2, S. Adamowicz1, A. Giebl3, E. Kilger1, M. Spannagl2, P. Möhnle2,1

  • Abstract Number: PB0050

    The Relationship of 4 Factor PCC or Plasma to INR and Factor Levels: An Exploratory Analysis of 2 Clinical Trials

    C. Hood1, P. Bajcic1, B. Goldstein1, J. Goldstein2, T. Milling3, M. Refaai4, R. Sarode5

  • Abstract Number: PB1109

    The RIETE Score: A Useful Screening Tool for Occult Malignancy in VTE and STP?

    D. McBriar1, B. Jacob2, G. Benson1

  • Abstract Number: LPB0064

    The Role of Activated Thrombin Activatable Fibrinolysis Inhibitor on Thrombus Stability in Venous Thromboembolism

    J. Chessum1,2, S. Shaya1,2, S. Cerroni2,3, D. Rajab1, J. Zhou2, J.C.M. Meijers4,5, J. Weitz1,2,3,6, P. Gross1,2,3, P. Kim1,2,3

  • Abstract Number: OC 34.2

    The Role of Acute-phase Circulating miRNAs in Modulating Clinical Outcome in Patients with Venous Thromboembolism

    V. Ten Cate1,2, S. Rapp1, A. Schulz1, T. Koeck1,3, J.H. Prochaska1,2,3, A. Pallares Robles2, K. Jurk2, M. Panova-Noeva1,2, S.-O. Tröbs1,3, C. Espinola-Klein4, M. Halank5, H.-J. Seyfarth6, S.V. Konstantinides7,8, T. Münzel4,3,7, K.J. Lackner9,3, M.A. Andrade-Navarro10, P.S. Wild1,2,3

  • Abstract Number: PB0275

    The Role of D-dimer in Prognosis of Patients with Pulmonary Thrombembolism: Some Aspects for COVID-19

    M. Bosevski1, G. Krstevski1, E. Dodic2, K. Kapsarov3, N. Petkovic4, National Registry on Venous Thrombembolism

  • Abstract Number: PB0569

    The Role of Familial Mediterranean Fever in Hemophilia: Should We Tested?

    S. Kirkiz1, Z. KAYA1, S. Gönen1, Ü. Koçak1

  • Abstract Number: PO192

    The Role of Hydroxychloroquine in a Secondary Prevention of Recurrent Thrombosis in Patient with Thrombophilia and Antiphospholipid Syndrome. A Case Report

    A. Movsisyan1, I. Karapetyan2, A. Harutyunyan2, H. Grigoryan1, L. Hambardzumyan2, J. Simonyan2, N. Sargsyan1,2, G. Tamamyan1,2, S. Danelyan1, L. Sahakyan1, H. Khachatryan1,2

  • Abstract Number: PB0956

    The Role of Matrix-metalloproteinase 9 in Bone Marrow Remodeling after Total Body Irradiation and Hematopoietic Stem Cell Transplantation

    K. Mott1, D. Semeniak1, H. Schulze1

  • Abstract Number: PB1039

    The Role of Nitric Oxide and Cationic Groups in Cardiovascular and Respiratory Toxicity of Protamine Sulfate in Zebrafish and Rodent

    J. Miklosz1, B. Kalaska1, P. Podlasz2, M. Chmielewska-Krzesinska2, M. Zajaczkowski3, A. Kosinski3, D. Pawlak1, A. Mogielnicki1

  • Abstract Number: PB1020

    The Role of Platelet CLEC-2 and GPVI in Rhabdomyolysis-induced Acute Kidney Injury

    S. Oishi1, N. Tsukiji2, S. Otake2, N. Oishi3, T. Sasaki2, T. Shirai2, Y. Yoshikawa2, K. Takano2, H. Shinmori4, T. Inukai5, T. Kondo3, K. Suzuki-Inoue2

  • Abstract Number: OC 07.2

    The Role of Point-of-Care Musculoskeletal Ultrasound for Routine Joint Evaluation and Management Considerations in Hemophilia Clinic

    N. Gallastegui1, R.F.W. Barnes1, C. Hanacek1, R. Kruse-Jarres2, B.U.K. Steiner2, D.V. Quon3, C. Bailey3, A. von Drygalski1,4

  • Abstract Number: PB1089

    The Role of Primary Thromboprophylaxis in People with Cancer: A Systematic Review and Meta-analysis

    F.A. Dewar1, K.M. Musgrave1, J. Simpson1, J. Hanley2

  • Abstract Number: LPB0033

    The Role of RAP1 Signaling in Platelet-coagulation Interplay

    A. Ballard1, D. Adalsteinsson2, E. O’Shaughnessy3, D. Paul1, R. Lee1, W. Bergmeier1

  • Abstract Number: PB0968

    The Role of Septins in Platelet Structure and Function

    O.V. Kim1, O. Vagin2, R.I. Litvinov1, J.W. Weisel1

  • Abstract Number: PB0007

    The Role of TEC Family Kinases in oxLDL-mediated Platelet Activity in vitro and Platelet and Endothelial Dysfunction in vivo

    T. Kohs1, T. Zheng1, I. Parra-Izquierdo1, S. Olson1, A. Xie1, J. Hodovan1, M. Muller1, C. McArthur1, J. Johnson1, M. Wallisch1, C. Lorentz1, N. Verbout1, P. Kievit1, M. Larson2, J. Aslan1, C. Puy1, J. Lindner1, O. McCarty1, J. Shatzel1

  • Abstract Number: OC 41.4

    The Role of the Thrombin/PAR Axis in the Anti-tumor CD8+ T Cell Response Following Immune Checkpoint Inhibition Therapy

    R. Cantrell1,2,3, L. Rosenfeldt3, B.K. Sharma3, B. Gourley3, A. Revenko4, B. Monia4, J. Palumbo3

  • Abstract Number: PB0250

    The Role of Thromboelastography and Follow-up of Fibrinolysis in Evaluating the Course of the Disease, Treatment Response, and Outcome of Pediatric Patients with COVID-19

    T. Hilkay Karapınar1, E. Böncüoğlu1, Y. Oymak1, E. Kıymet1, Ö. Tüfekçi2, A. Akaslan Kara1, K. Ötiken Arıkan1, Ş. Şahinkaya1, T. Çelik1, S.N. Bayram1, İ. Devrim1, H. Ören2

  • Abstract Number: PO119

    The Role of Thromboelastography in Search for Drug-candidates

    D. Lipatov1, V. Korunas1, K. Enikeeva1, R. Kamilova1, L. Bashirova1, I. Bashirov1, A. Samorodov1

  • Abstract Number: PB1104

    The Role of Thrombophilia in Asparaginase Related Venous Thromboembolism in Pediatric and Young Adult Patients Affected by Acute Lymphoblastic Leukemia

    A. Serrao1, G.M. Assanto1, C. Santoro1, S. Bianchi1, S. Olivieri2, M. Canichella1, A.M. Testi1, A. Chistolini1

  • Abstract Number: PB1165

    The Role of Thrombophilia in Deep Vein Thrombosis of Unusual Sites

    I. Chabchoub1, R. Ben Salah1, F. Megdiche2, C. Kallel2, Z. Bahloul1

  • Abstract Number: PB1043

    The Role of Transforming Growth Factor ß1 (TGFß1) and Fibrinogen in the Induction of Adhesive Properties of Vascular Endothelium (HUVECS) and the Spread of Acute Lymphoblastic Leukemia (ALL)

    V. Barilka1, V. Matlan1, S. Prymak1, O. Shalay1

  • Abstract Number: OC 38.1

    The Role of VWF/FVIII Association in Anti-FVIII Immune Responses in Hemophilia A Mice

    Y. Cai1,2, W. Jing2, J.A. Schroeder1,2, Q. Shi1,2,3,4

  • Abstract Number: PB1196

    The Roles of Individual and Neighborhood Income on Regional and Racial Differences in Risk of Venous Thromboembolism in the United States: The REasons for Geographic and Racial Differences in Stroke Study (REGARDS)

    J. Munger1, K. Wilkinson2, I. Koh2, L. Long3, G. Lovasi4, L. McClure4, J. Brown4, G. Howard3, V. Howard3, T. Plante1,5, M. Cushman2,5, N. Zakai2,5

  • Abstract Number: PB0547

    The Safety of Eptacog Beta in Hemophilia Patients with Inhibitors in Adult, Pediatric, and Perisurgical Settings

    J. Mahlangu1, M. Escobar2, M. Callaghan3, J. Ducore4, P. De Moerloose5, C. Hermans6, G. Castaman7, J.-F. Schved8, J. Journeycake9, C. Leissinger10, J. Luck11, D. Quon11, M. Recht12, R. Sidonio Jr13, A. Srivastava14, M. Wang15, G. Young16, D. Bonzo17, N. Chambron18, C. Kessler19

  • Abstract Number: PB0829

    The Spectrum of Immune Thrombocytopenia with COVID-19 Infection

    I. Muhsen1, J. Petkova1, L. Rice1

  • Abstract Number: PB0128

    The Thickness of Fibrin Fibers is Associated with High Fibrin Clot Visco-elasticity in Carcinomatosis Patients

    M. Ullah1, S. Mirshahi2,1, I. Aldybiat1, G. Contant2, M. Pocard1, J. Soria1, M. Mirshahi1

  • Abstract Number: OC 58.3

    The Tumor Promoting Activity of Osteopontin Is Solely Dependent on its Cleavage by Thrombin

    S. Peraramelli1, Q. Zhou1, Q. Zhou1, B. Wanko1, T.H. Leung2, S. Mizuno3, M. Ito4, T. Myles1, T.M. Stulnig5, J. Morser1, L.L. Leung1

  • Abstract Number: PB1123

    The Use of DOACS in Catheter Related Thrombosis in Cancer

    U. Faruqi1, G. Bahra1, P.-L. Luo1, Z. Mahir1, A. Danaee1

  • Abstract Number: PB0431

    The Use of Emicizumab for Acquired Hemophilia A at US Hemophilia Treatment Centers

    J. Poston1, R. Kruse-Jarres2

  • Abstract Number: PB1056

    The Utility of the Dilute Prothrombin Time Assay in the Diagnosis of Antiphospholipid Syndrome

    T. Storozuk1, G. Wool1

  • Abstract Number: PB0841

    The Value of a Rapid, On-demand ADAMTS13 Activity Assay for the Diagnosis of Thrombotic Thrombocytopenic Purpura

    A. White1, R. Martin1, K. Sew2, A. Stucke3, R. Cook1

  • Abstract Number: PB0944

    The von Willebrand Disease-Woman (VWD-Woman) Trial: A Pilot Study Comparing Recombinant von Willebrand Factor (rVWF) plus Tranexamic Acid (TA) vs. rVWF Alone in the Prevention of Postpartum Hemorrhage in Women with von Willebrand Disease

    N. Machin1, S. Caritis1,2, C. Seaman1,3, M. Brooks1, D. Vehec1,3, M. Rode1,3, D. Ivanco1,3, D. Fischer2, D. Zowacki2, M. Ragni1,3

  • Abstract Number: LB 02.1

    The VWF-A1 domain binding aptamer BT200 prolongs the half-lives of different factor VIII (FVIII) products in patients with severe hemophilia A and increases FVIII levels in non-severe hemophilia A

    C. Ay1, U. Derhaschnig2, B. Jilma2, C. Schoergenhofer2, K. Kovacevic2, P. Quehenberger3, P. Jilma3, J.C. Gilbert4, S. Zhu4, D. Kraemmer1, A. Iorio5, I. Pabinger1

  • Abstract Number: PB0661

    The World Federation of Hemophilia Gene Therapy Registry

    B.A. Konkle1,2, D. Coffin3, M. Naccache2, C. Clark4, L.A. George5, A. Iorio6, W. Miesbach7, D. Noone8, F. Peyvandi9,10, S.W. Pipe11, M. Recht12, M. Skinner13, L.A. Valentino14, J.N. Mahlangu15,16, G.F. Pierce2

  • Abstract Number: OC 48.3

    Therapeutic Knockdown of Plasminogen with siRNA in Hemophilia A and von Willebrand disease Mouse Models

    P. Batty1, A. Strilchuk2, K. Nesbitt1, A. Yong2, D. Lillicrap1, C. Kastrup2

  • Abstract Number: PB0818

    Therapeutic Landscape in Primary Immune Thrombocytopenia (ITP) over the Last Three Decades in the United Kingdom (UK Adult Primary ITP Registry Project)

    P. Raheja1, H. Miah1, A. Miah1, N. Cooper2, M. Scully3, T. Biss4, S. Chattree5, D. Allsup6, G. Evans7, S. Pavord8, G. Matthias9, C. Bagot10, Q. Hill11, C. Bradbury12, V. Martlew13, S. Johns14, L. Taylor1, A. Newland1, D. Provan1, V. McDonald1, On behalf of the United Kingdom adult primary ITP registry

  • Abstract Number: PB0403

    Thermal Shift Assay to Probe Melting of Thrombin, Fibrinogen, Fibrin Monomer and Fibrin: Gly-Pro-Arg-Pro Induces a Fibrin Monomer-like State in Fibrinogen

    J. Crossen1, S. Diamond1

  • Abstract Number: PB0846

    Thirty-five Years of Follow up of a Patient with Congenital Thrombotic Thrombocytopenic Purpura

    M. de Oliveira1, C. Casais1, C. Gonçalves1, E. Cruz1, M. Coutinho1, M. Pereira1, J. Coutinho1, S. Morais1

  • Abstract Number: OC 12.2

    Three Available Risk Scores Modestly Predict Hemorrhage in Patients with Cancer-associated Thrombosis (CAT)

    K. Sanfilippo1,2, S. Luo1,2, A. Khorana3, B. Gage1

  • Abstract Number: PB0307

    Thrombin Generation (TG) Reveals Underlying Hypercoagulable Process in COVID-19 Patients Despite Low Molecular Weight Heparin (LMWH) Therapy

    A. Scazziota1,2, S. Pons1, M.d.L. Herrera1, S. Aguirre1, V. Monserrat1

  • Abstract Number: OC 18.4

    Thrombin Generation Assay for Rivaroxaban, Apixaban, and Edoxaban Measurements: A Prospective Multicenter Cross-sectional Study

    T. Meihandoest1, J.-D. Studt2, A. Mendez3, L. Alberio4, P. Fontana5, W.A. Wuillemin6, A. Schmidt7, L. Graf8, B. Gerber9, G.M. Maeder1, C. Bovet1, T.C. Sauter10, M. Nagler1

  • Abstract Number: PB0105

    Thrombin Generation Assay in Crohn Disease

    H. Ben Youssef1, H. Baccouche1, S. Meriem1, C. Aya1, F. Monia1, J. Boubaker1, N. Ben Romdhane1

  • Abstract Number: PB0465

    Thrombin Generation by Genesia in Patients with Haemophilia A and Inhibitors during Immune Tolerance Induction

    T. Szanto1,2, E. Lehtinen1, M. Lemponen2, R. Lassila1,2

  • Abstract Number: PB0543

    Thrombin Generation Capacity of Patients with Severe Haemophilia Receiving Prophylaxis (HOPE Study)

    S. Meunier1, A. Lienhart1, M. Trossaert2, V. Gay3, C. Berger4, B. Tardy4, F. Volot5, Y. Dargaud6

  • Abstract Number: PB0613

    Thrombin Generation in Hemophilia A Patients after Infusion of Recombinant and PlasmadDerived Factor VIII Concentrates

    O. Smirnova1, O. Matvienko1, V. Burakov1, V. Soldatenkov1, K. Komissarov1, L. Papayan1

  • Abstract Number: PB1157

    Thrombin Generation in Newly Diagnosed Multiple Myeloma

    D. Velasco-Rodríguez1, I. Martínez-Alfonzo1, A. Velasco-Valdazo2, R. Vidal Laso1, C. Díaz1, N. Revilla3, A. García-Raso1, J.M. Alonso-Domínguez1, S. Martín-Herrero1, E. Askari1, E. Prieto1, M.J. Blanchard3, F.J. López-Jiménez3, P. Llamas-Sillero1,2

  • Abstract Number: PB0124

    Thrombin Generation is Affected by Freezing Independent of Storage Temperature

    M. Ninivaggi1, A. Carlo2, R. de Laat - Kremers1, B. de Laat1

  • Abstract Number: PB0156

    Thrombin Generation Kinetics, Neutrophil Extracellular Traps, and von Willebrand Factor in COVID-19 Associated Coagulopathy: A Pilot Study

    T. MacArthur1, J. Goswami1, M. Sridharan2, J. Tange2, A. Kirmse1, K. Lundell1, M. Auton2, T. Chon3, R. Hurt3, B. Salonen3, R. Ganesh3, J.-F. Dong4, R. Kozar5, S. Heller1, E. Loomis1, A. Johnstone6, K. Bailey7, G. Spears7, M. Park1

  • Abstract Number: OC 14.4

    Thrombin Generation Rescued in Hemophilia A by Low-normal Levels of FV Is Confirmed to Be Partially due to Substrate Competition

    M. Stobb1, A. Fogelson2, S. Sindi3, K. Leiderman4, K. Neeves5, D. Monroe6

  • Abstract Number: PB1291

    Thrombin Generation Test and Use of Combined Oral Contraceptive

    M. Sousa1, R.C. Figueiredo Duarte1, M.d.G. Carvalho1, I.d.F. Oliveira Silva1, D. Serenini1, L. Dusse1

  • Abstract Number: OC 77.4

    Thrombin Mediated Activation of Protease Activated Receptor 1 Contributes to Doxorubicin Induced Cardiac Injury

    S. Grover1, J. Posma1,2, J. Griffin3, N. Mackman1, S. Antoniak1

  • Abstract Number: OC 27.1

    Thrombin Spatial Distribution Determines the Contribution of Activated Protein C to Endogenous Anti-coagulant Activity during Hemostasis and Thrombosis in vivo

    T. Marar1,2, C. Matzko2, J. Wu2, C. Esmon3, T. Sinno2, L. Brass2, M. Tomaiuolo2, T. Stalker1,2

  • Abstract Number: LPB0144

    Thrombocytopenia in Pregnancy: Identification and Management at a Reference Centre in Pakistan

    M. Borhany1, M. Abid1, S. Zafar1, T. Shamsi1

  • Abstract Number: PB0419

    Thromboelastography for the Evaluation and Management of Patients with Traumatic Brain Injury

    J. Dias1, J. Hartmann1, J. Cannon2

  • Abstract Number: PB0669

    Thromboelastography to Monitor Periprocedural Hemostasis in Advanced Liver Disease: A Systematic Review and Meta-analysis

    J. Hartmann1, J. Dias1, E. Pivalizza2, G. Garcia-Tsao3

  • Abstract Number: PB1094

    Thromboembolic and Bleeding Complications fFowing Surgery among Patients with Ovarian Cancer – A Single Centre Retrospective Cohort Study

    H.M. Wiegers1, M. Schaafsma1, H. Zelisse1, N. van Es1, S. Middeldorp2, C.H. Mom1

  • Abstract Number: PB1284

    Thromboembolic disease (VTE) and Inmune Trombocytopenia (ITP): A Case Report

    M. R. Lopez1, E. Lopez Ansoar1, A. Nieto Vazquez1, C. Albo Lopez1

  • Abstract Number: PB0721

    Thromboembolic Disease in Severe Factor V (FV) Deficiency: A Case Report: “Anticoagulating the Anticoagulable”

    M. R. Lopez1, E. Lopez Ansoar1, A. Nieto Vazquez1, C. Albo Lopez1

  • Abstract Number: PB0292

    Thromboembolism and Coagulopathy in COVID-19: A Review of Quality Indicators at Sunnybrook Health Sciences Centre

    A. Suleman1, S. Carlin2, W. Geerts2

  • Abstract Number: PB1190

    Thromboembolism is Prevalent and Adversely Affects Overall Survival in Adults with Hemophagocytic Lymphohistiocytosis

    J. Croden1, L. Bilston2, J. Grossman3, H. Sun4

  • Abstract Number: PB1007

    Thrombogenic Potential in Patients Undergoing Hemodialysis Using Central Venous Catheter and Arteriovenous Fistula

    M. Dumont Cunha1, M. Henrique Fernandes Ottoni1, M. Araújo Figueiredo1, T. Coaglio Lucas1

  • Abstract Number: PB0422

    Thrombolysis and Anti-cancer Activity of Koji-Natto (Kojikinase)

    H. Sumi1, T. Mitsuo2, C. Yatagai1

  • Abstract Number: PB0424

    Thrombolytic Activity of Pearl-like Tempeh

    H. Sumi1, Y. Yanagisawa2, S. Naito1, C. Yatagai1

  • Abstract Number: PO166

    Thrombophilia and Thromboembolic Venous Disease in Southern Tunisia

    I. Chabchoub1, R. Ben Salah1, F. Megdiche2, C. Kallel2, Z. Bahloul1

  • Abstract Number: PB1293

    Thromboprophylaxis in High-risk Obese Pregnant Women: How Much Is Enough?

    A. Rodríguez Alén1, M. De la Torre De la Paz1, N. Rollón Simón1, S. Daza Pozo1, M.O Abío Calvete1, L. Parrilla Navamuel1, G. Figaredo García-Mina1, M. Jiménez Sánchez2, O. Rodríguez Gómez2, A. García López2, S. Moreno Ramírez1, K.G. Albiño Salazar1, J. Cuesta Tovar1

  • Abstract Number: PB0237

    Thrombosis and Bleeding in Critically Ill COVID-19 Patients at Higher than Prophylactic Dose of Heparins

    A. Mavri1, M. Lukić2, M. Mavrič2, N. Šoštarič2, D. Zupančič2

  • Abstract Number: PO184

    Thrombosis in Elderly: Watch out Antipsychotic Agents!

    M. Mrouki1, H. Hamitou1, P. Tissot1, I. Lusamvuku1, S. Maillard1, C. Bonhoure1

  • Abstract Number: PB1135

    Thrombotic and Hemorrhagic Complications in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

    E. Gonzalez Gomez1, N. Fernandez Mosteirin1, M. Moreno Carbonell1, S.F. Pinzon Mariño1, A. Garcia Ortego1, A. Gomez Martinez1, C.F. Hernandez Mata1, S. Martin Consuegra1, M. Civeira Marin1, A. Lopez Peña1, C. Rodriguez Lefler1, M.S. Ordas Miguelez1, M.d.M. Herrero Gutierrez1, P.E. Lopez Gomez1, M.P. Delgado Beltran1, J.M. Calvo Villas1

  • Abstract Number: LPB0123

    Thrombotic Complications in a Cohort of Children with Myeloproliferative Neoplasms

    N. Kucine1, V. Vanderpoel2, K. Shimano2

  • Abstract Number: OC 40.1

    Thrombotic Complications in Pediatric Patients Hospitalized with COVID-19 Disease or Associated Multisystem Inflammatory Syndrome in Children (MIS-C)

    M. Torres1, J. Tilley1, M. Trang1, A. Schenk1

  • Abstract Number: PB0147

    Thrombotic Events in COVID-19 Are Associated with a Lower Use of Prophylactic Anticoagulation Before Hospitalization and Followed by Decreases in Platelet Reactivity

    C. Clark1, B. Jukema1, A. Barendrecht1, J. Spanjaard2, N. Jorritsma2, S. Smits1, S. de Maat1, C. Seinen1, S. Sebastian1, A. Koekman1, A. van Wesel1, H. van Goor3, R. Spijkerman2,4, S. Bongers2,5, E. van der Vries1, S. Nierkens2, M. Boes2, L. Koenderman2,4, K. Kaasjager3, C. Maas1

  • Abstract Number: PB0881

    Thrombotic Microangiopathies (TMA): In vivo Evidence for Platelet Activation and Endothelial Cell Injury, and Potential for Therapeutic Intervention with Defibrotide

    S. Elhadad1, S. Subrahmanian2, J. Ahamed2, J. Laurence1

  • Abstract Number: PB0163

    Thrombotic Microangiopathy in Two Patient with Covid 19 Disease

    P. Bradacova1, L. Slavik2, J. Ullrychova1, J. Ulehlova2, J. Prochazkova2, A. Hlusi2

  • Abstract Number: PB0212

    Thrombotic Risk of Hospitalized Patients with COVID-19 and a Co-infection

    I. Akpan1, L. Van Doren1, J. Travers2, K. Runcie1, A. Wei1, J. Cogan1, Y. Pumpalova1, D. Diuguid1, A. Eisenberger1, R. Francis1

  • Abstract Number: PB0815

    Time Course of Response to Fostamatinib, an Oral Spleen Tyrosine Kinase (SYK) Inhibitor for the Treatment of Immune Thrombocytopenia (ITP)

    M. Sholzberg1, D. Arnold2, D. Liles3, R. Numerof4, M. Boxer5

  • Abstract Number: PB0142

    Time Course of the Development of Immunothrombosis during COVID-19 Hospitalization

    J. Oliveira1, G. Vieira-Damiani1,2, G. Locachevic3, J. Mariolano3, K. Soares3, A. Santos1, B. Jacintho1, C. Vaz1, G. Mesquita1, E. Paula4,5, F. Orsi4,3

  • Abstract Number: PB0560

    Time from the Inhibitor Detection to the Start of Immune Tolerance Induction and the Outcome of Immune Tolerance Induction: Results from the Brazilian Immune Tolerance (BrazIT) Study

    R.M. Camelo1,2, M.M. Dias1, C. Caram-Deelder2,3, S. Gouw4, L.P. de Magalhaes1, L.W. Zuccherato1, L.L. Jardim1,2, J. van der Bom2,3, S.M. Rezende1

  • Abstract Number: PB0553

    Tissue Factor Pathway Inhibitor (TFPI) Levels and Bleeding Risk in Patients with Severe Hemophilia A or B

    B. Tardy-Poncet1,2,3, A. Montmartin3, F. Genre-Volot4, H. Chambost5, E. De Maistre4, P. Morange5, L. Ardillon6, Y. Dargaud7, A. Lienhart7, P. Nguyen8, B. Frotscher9, B. Wibaut10, C. Derory2, M. Delolme1, B. Tardy2

  • Abstract Number: PB0153

    Tissue Factor-stimulated Plasma Thrombin Generation Is Enhanced in Hospitalised Patients with COVID-19 Despite Pharmacological Thromboprophylaxis

    S. Kelliher1,2, L. Weiss2,3, S. Cullivan4,2, E. O'Rouke1, C. Murphy2,5, S. Toolan1, A. Lennon1, P.B Szklanna2,3, S. Comer2,3, H. Macleod2, S. Gaine4,6, K. O'Reilly4,6, B. McCullagh4,6, J. Stack7,6, P.WG Mallon6,8,9, A. Cotter6,9,10, P.B Maguire2,3,11, F. Ní Áinle1,2,6,12,13, B. Kevane1,2,6,13

  • Abstract Number: PB0008

    Tissue Inhibitor of Metalloproteinases-1 (TIMP1) is Related to Residual Thromboxane Dependent Platelet Activation in Patients with Type 2 Diabetes Mellitus Receiving Low Dose Aspirin

    P. Simeone1, R. Tripaldi1, R. Liani1, S. Ciotti1, V. Cavalca2, M. Camera2, E. Tremoli2, F. Santilli1

  • Abstract Number: LPB0005

    Tissue-engineered Human Arteries Replicate Primary and Secondary Haemostatic Functions Seen in vivo: A Replacement for Mouse Arterial Thrombosis Models?

    J. Ranjbar1, Y. Yang1, A. Harper1

  • Abstract Number: PB0075

    Titanium Compounds Bind and Activate Factor XII and Prekallikrein

    M. Litvak1, A. Matafonov1, A. Shamanaev1, A. Kobrin1, A. Gruber2,3, O.J. McCarty2, D. Gailani1

  • Abstract Number: PB0441

    To Treat or Not? Remission Induction of Acquired von Willebrand Syndrome Secondary to Chronic Lymphocytic Leukemia: A Case Report

    R. Khalife1, A. Aw1, L. Duffett1, O. Radhwi1, L. Lacasse1, L. Huebsch1, M. Bowman2, P. James2, A. Tinmouth1

  • Abstract Number: LB 02.2

    Towards Understanding ChAdOx1 nCov-19 Vaccine-induced Immune Thrombotic Thrombocytopenia (VITT)

    A. Greinacher1, K. Selleng1, J. Wesche1, S. Handtke1, R. Palankar1, U. Völker2, T. Thiele1, F. Siegerist3, N. Endlich3, C. Rangaswamy4, R.K Mailer4, H. Englert4, M. Frye4, T. Warkentin5, T. Renne4

  • Abstract Number: PB0410

    Tranexamic acid for Hyperacute Primary Intracerebral Haemorrhage (TICH-3): Protocol for a Multinational Phase 3 Placebo-controlled Randomised Trial

    M. Desborough1,2, R. Al-Shahi Salman3, T. Coats4, R. Dineen5, T. England6, D. Havard5, T. Hepburn7, S. Hodgson5, M. James6, A. Montgomery6, C. Rick6, I. Roberts8, T. Robinson4, C. Roffe9, D. Werring10, P. Bath5, N. Sprigg5

  • Abstract Number: PB0412

    Tranexamic Acid to Reduce Bleeding in Patients Treated with Non-Vitamin K Oral Anticoagulants Undergoing Dental Extraction: The EXTRACT-NOAC Randomized Clinical Trial

    A. Ockerman1, I. Miclotte1, M. Vanhaverbeke2, T. Vanassche2, A. Belmans1, J. Vanhove3, J. Meyns4, N. Nadjmi5,6, G. Van Hemelen6, P. Winderickx6, R. Jacobs1,7, C. Politis2, P. Verhamme2.

  • Abstract Number: OC 31.1

    Transcription Factor RUNX1 Regulates Factor XIIIA Subunit (F13A1) Expression in Platelets and Megakaryocytic Cells: Decreased Platelet F13A1 Expression and Clot Retraction in RUNX1 Haplodeficiency

    F. Del Carpio-Cano1, N. Songdej2, G. Mao3, J. Wurtzel4, L. Goldfinger4, M.P. Lambert5, AK. Rao6

  • Abstract Number: OC 13.4

    Transcriptional Analysis of the Response to Stimulation in ECFCs Derived from Type 1 VWD Patients

    R. Kloosterman1, M. Zago-Schmitt1, J. Grabell2, L. Thibeault3, M. Bowman2, P.D.A. Lima4, K. Tyryshkin1, C.C.T. Hindmarch4, N. Renwick1, P. James2

  • Abstract Number: OC 29.4

    Transcriptomics and Proteomics to Study the Effect of Hyperactive SRC Kinase during Megakaryopoiesis

    L. De Kock1, F. Ver Donck1, C. Thys1, C. Van Geet1, K. Freson1

  • Abstract Number: PB1290

    Transferability of the ETP-based APC Resistance Assay on the ST Genesia System

    L. Morimont1,2, M. Didembourg1, J.-M. Dogné1, A. Carlo3, J. Douxfils1,2

  • Abstract Number: PB0304

    Transient Lupus Anticoagulant Presence in COVID-19 Pneumonia, a Probably Epiphenomenon

    M. Martinuzzo1,2, M.S. López1,2, I. Carboni Bisso3, I. Huespe4,5, M. Las Heras3, E. Prado3, V. Privitera6, M. Garbarini3,6, L. Barrera7,2, J. Sinner3

  • Abstract Number: OC 14.1

    Transplacental Delivery of Maternal FVIII for Induction of FVIII-specific Immune Tolerance

    A. Mimoun1,2,3, M. Bou Jaoudeh1,2,3, I. Peyron4,5, V. Daventure1,2,3, S. Delignat1,2,3, A. Reyes Ruiz1,2,3, O. Christophe4,5, P. Lenting4,5, C. Denis4,5, S. Lacroix-Desmazes1,2,3

  • Abstract Number: OC 48.2

    Transplacental Delivery of Recombinant Fc-fused Factor VIII (rFVIIIFc) in FVIII-deficient Mice

    A. Reyes-Ruiz1,1, S. Delignat1, A. Mimoun1, A. Azam1, D. Lillicrap2, S. Lacroix-Desmazes1

  • Abstract Number: PO112

    Treatment of Advanced Atherosclerotic Plaque with Neovascularization Using B-mode Ultrasound-guided HDL-loaded Microbubbles-mediated Low Level Focused Electrohydraulic Shock Wave Sonoporation Therapy and Cholesterol Diet Withdrawal

    H. Mehrad1,2, A. Foletti3,2

  • Abstract Number: PB1116

    Treatment of Cancer-associated Thrombosis with Six Months of Prophylactic-dose Enoxaparin after Initial Full-dose Anticoagulation: A Pilot Study

    J. Popov1, S. Coelho2, M. Carrier3, C. Sperlich4, S. Solymoss5,6, N. Routhier7,8, S. Shivakumar9,10, W. Aibibula2, S. Kahn1,2, V. Tagalakis1,2

  • Abstract Number: LPB0075

    Treatment of Catheter-related Arterial Thrombosis in Children: A 15-year Single Center Experience

    O. Crameri1, M. Rizzi2, M. Albisetti1.

  • Abstract Number: PB0833

    Treatment of Immune Thrombocytopenia (ITP) in the COVID-19 Era: Fostamatinib, an Oral Spleen Tyrosine Kinase (SYK) Inhibitor

    N. Cooper1, A. Charania2, A. Hart3, C. Ademokun3, R. Numerof4

  • Abstract Number: PB1115

    Treatment of Venous Thromboembolism (VTE) Events with Cancer as a Risk Factor in a Teaching Hospital: 2015 – 2020

    H. Rowswell1, T. Nokes1

  • Abstract Number: PB0518

    Treatment Patterns and Clinical Outcomes among Patients with Hemophilia A Treated with Factor VIII Replacement Therapies and Nonfactor Therapy: An Assessment of US Real-world Data

    A. Adeyemi1, A. Cockerham1, R. Preblick1, A. Swenson2, J. Dumont1

  • Abstract Number: OC 25.1

    Trends in Venous Thromboembolism and Death in COVID-19 Positive Patients in 2020

    A. Pasha1, R. Chaudhary1, L. Padrnos2, E. Wysokinska3, R. Pruthi1, M. Sridharan1, P. Daniels1, R. McBane1, D. Houghton1

  • Abstract Number: PB1212

    Trombophilia and Other Risk Factors of Cerebral Venous Sinus Thrombosis in 255 Patients

    A. Gwozdowska1, E. Odnoczko2, B. Baran2, J. Windyga1,2, A. Gwozdowska, E. Odnoczko, B. Baran, 1,2 J. Windyga

  • Abstract Number: PO146

    TSUBASA Study: An Observational Study of Emicizumab to Evaluate Physical Activity, Bleeding Events, Quality of Daily Life, and Safety in People with Hemophilia A without FVIII Inhibitors

    K. Nogami1, T. Fujii2, A. Sawada3, A. Nagao4, C. Nagae5, N. Suzuki6, M. Nojima7, D. Nosaka8, T. Nakamura8, S. Yoshida8, K. Amano9

  • Abstract Number: PB0849

    TTP during Pregnancy: Acquired or Late-Onset Congenital? A Diagnostic Challenge

    S. Demeester1, N. De Beule1, C. Orlando1, A. De Becker1, K. Jochmans1

  • Abstract Number: PB0746

    Tumor Cell-induced Platelet Aggregation is Sustained by Platelet Entrapment into the Fibrin Network Formed by Thrombin

    I. Tesakov1, A. Filkova2,3,4, A. Deputatova4, A. Korneichuk4, S. Obydennyi2,3, I. Kireev5, M. Panteleev2,3,4, A. Sveshnikova2,3,4

  • Abstract Number: OC 30.2

    Tumor Gene Expression Associates with Venous Thromboembolism in Patients with Pancreatic Cancer

    F. Bosch1,2, F. van Dijk2, S. Briedé3, J. Groen4, R. Hanna-Sawires4, F. Klok4, H. Kaasjager3, L. Brosens3, I. Molenaar3, B. Bonsing4, J. Mieog4, M. Besselink2, O. Busch2, J. Verheij2, A. Farina-Sarasqueta2, J. Wilmink2, M. Bijlsma2, H. Versteeg4, N. van Es2, J.T. Buijs4

  • Abstract Number: PB1140

    Tumor Somatic Mutations as Predictors of CDK4/6 Inhibitor Associated Thromboembolism in Women with Metastatic Breast Cancer

    M. West1, R. Thawani1,1, J. Shatzel1

  • Abstract Number: PB0685

    Twelve Months of Emicizumab Prophylaxis in a Severe Hemophilia A Man with Inhibitor who Failed Immune Tolerance Induction: Effectiveness, Economic, and Safety Outcomes

    R.M. Camelo1, T.C. de Medeiros2, D.G.B. de Albuquerque2, N. Dantas-Silva3, J. Álvares-Teodoro4

  • Abstract Number: PB0683

    Twelve Months of Emicizumab Prophylaxis in a Woman with Mild Hemophilia A and Inhibitor: Effectiveness, Safety and Economic Outcome

    R.M. Camelo1, E.S. Casaretto2, M.D. Castro Tenório2, N. Dantas-Silva3, S.S. de Figueiredo2, J. Álvares-Teodoro4

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