ISTH 2021 Congress Archives - Page 2 of 91

Abstract Number: PB0715

Safe and Effective Prophylaxis with Plasma-derived Factor X Concentrate in an Elderly Patient with Hereditary Factor X Deficiency

M. Reding¹, S. Peltier¹, K. Clark²
Abstract Number: PB1133

Safety and Effectiveness of an Institutional Recommendation on the Management of Cancer Associated Venous Thrombosis: Results of a Real World Study with One-year Follow-up

C. Rothschild¹, A.A.G.S. Brandão¹, A. Duran¹, A.E. Zerati¹, G.F. Saes¹, C.S. Bittar¹, I.B.S.d.S. Costa¹, M.H.H.d.S. Rehder¹, S.M.R. Fonseca¹, M.D.P.E. Diz¹, L.B.d.O. Alves¹, J. Pereira¹, V. Rocha¹
Abstract Number: PB0503

Safety and Efficacy of Concizumab Prophylaxis Following a Switch from rFVIIa on-demand Treatment: Sub-analysis Results from the Phase 2 Explorer4 Trial in Patients with Hemophilia A or B with Inhibitors

A. Shapiro¹, K. Cepo², S.M. Tønder³, G. Young⁴, V. Jiménez-Yuste⁵
Abstract Number: PB0722

Safety and Efficacy of Fibrinogen Concentrate in Congenital Fibrinogen Deficiency: A Post-marketing Observational Study

B. Schwartz¹, C. Solomon², S. Knaub², F. Peyvandi^3,4
Abstract Number: PB1221

Safety and Efficacy of Low-Molecular Weight Heparin Regimes for Venous Thromboembolism Prophylaxis in Bariatric Surgery

A. Li¹, A. Eshaghpour², G. Lee³, J. Deng⁴, R. Ikesaka⁵, M. Carrier⁶, M. Crowther⁵
Abstract Number: OC 76.4

Safety and Efficacy of the Direct Oral Anticoagulants in Cerebral Vein Thrombosis: A Systematic Review and Meta-analysis

F. Galea¹, I. Buhagiar¹, N. Riva², A. Gatt², J. Calleja-Agius¹
Abstract Number: LPB0004

Safety and Efficacy of Using Direct Oral Anticoagulants for Stroke Prevention in Atrial Fibrillation Patients with Pre-obesity and Obesity

Q. Chen¹, M.M. Toorop¹, S.C. Cannegieter¹, W.M. Lijfering¹
Abstract Number: OC 73.2

Safety and Efficiency of Diagnostic Strategies for Ruling out Pulmonary Embolism in Important Patient Subgroups: A Systematic Review and Individual-patient Data Meta-analysis

M.A.M. Stals¹, T. Takada², N. Kraaijpoel³, N. van Es³, HR Büller³, Y Freund⁴, J Galipienzo⁵, G Le Gal⁶, W Ghanima⁷, MV Huisman¹, JA Kline⁸, KGM Moons², S Parpia⁹, M Righini¹⁰, P-M Roy¹¹, M van Smeden², PS Wells⁶, K de Wit¹², GJ Geersing², FA Klok¹
Abstract Number: LPB0002

Safety and Pharmacokinetics of Direct Oral Anticoagulants after Bariatric Surgery: A Systematic Review

R. Leong¹, D.K Chu^2,3, M.A Crowther², S. Mithoowani²
Abstract Number: OC 06.3

Safety of Direct Acting Oral Anticoagulants (DOACs) in Comparison to Low Molecular Weight Heparin (LWMH) in Gastrointestinal and Genito-urinary Cancers

S. Rahman¹, J. Trias¹, M. Barouqa¹, M. Kushnir¹, H. Billett¹
Abstract Number: LPB0114

Safety of FEIBA and Emicizumab (SAFE): Dose Escalation Study Evaluating the Safety of in vivo Administration of Activated Prothrombin Complex Concentrate in Hemophilia A Patients with Inhibitors on Emicizumab

H. Kizilocak¹, E. Marquez-Casas¹, J. Malvar¹, G. Young²
Abstract Number: PB1247

Safety Profile of Rivaroxaban in First-time Users Treated for Deep Vein Thrombosis and Pulmonary Embolism without a Recent History of Cancer

A. Ruigomez¹, T. Schink², A. Voss², R.MC Herings³, E. Smits³, K. Swart-Polinder³, Y. Balabanova⁴, G. Brobert⁵, L.A. García Rodríguez¹
Abstract Number: PB1015

Salt Bridge Formation Between A1 Domain of von Willebrand Factor and Platelet Glycoprotein (GP) Ibα by Molecular Dynamics Simulations

M. Nakayama¹, S. Goto¹, S. Goto¹
Abstract Number: PO131

SARS-CoV 2 and Venous Thromboembolism: A Risk beyond Thromboprophylaxis

C. Gumpel¹, L. Cinara¹, M.C. De Paoli¹, S. Ciarlo¹, A. Rocaspana¹, J. Gnass¹, M. Bellantig¹, L. Welker¹, J.L. Fedele¹
Abstract Number: PB0136

SARS-CoV-2 Derived Peptides Potentiate Pro-inflammatory and Pro-coagulant Responses to the TLR3 Ligand Poly(I:C) in Human Endothelial Cells and Mice

V. Bharathi¹, Y. Zhang², G. Wong², N. Mackman¹, S. Antoniak¹
Abstract Number: OC 03.2

SARS-CoV-2 Infection of K18-hACE2 Transgenic Mice Induces an Early Hyperactive Phenotype in Circulating Platelets

S. Subramaniam¹, R.M. Hekman², A. Jayaraman¹, A.K. O'Connell^3,4, P. Montanaro^3,5, K. Ravid^6,7, N.A Crossland^3,5, F. Douam^4,3, A. Emili², M. Bosmann^6,3
Abstract Number: PB0157

SARS-CoV2 Spike Protein Can Activate Platelets through Integrin Alpha IIb Beta 3

C. Williams¹, J. Khalil¹, T. Walsh¹, K. Gupta¹, E. Aitken¹, S. Mundell¹, I. Berger¹, A. Poole¹, I. Hers¹
Abstract Number: PO115

Seasonal Changes of Platelet Aggregation Indexes at the Patients with Stable Angina

D. Shorikova¹, E. Shorikov¹, P. Shorikov¹
Abstract Number: PB1138

Secondary Prophylaxis of Venous Thromboembolism with Direct Oral Anticoagulants in Patients with Major Congenital Thrombophilia vs Non-thrombofilic Patients

A. Serrao¹, G.M. Assanto¹, C. Santoro¹, A. Pallotta², A. Chistolini¹
Abstract Number: PB0767

Selected Platelet Parameters in Patients with Rheumatoid Arthritis at Total Hip Arthroplasty

A.S. Ershov^1,2, I.P. Antropova^1,3, E.A. Volokitina¹, L.P. Evstigneeva^1,2
Abstract Number: PB0073

Selective Small Molecule Factor XIIa Inhibitor KV998083 Protects against FeCl3 Induced Arterial Thrombosis in Mice

S. Whitney¹, A. Clermont¹, N. Murugesan¹, H. Edwards², E. Duckworth², S. Pethen², S. Hampton², E. Feener¹
Abstract Number: PO157

Self-Administration of Romiplostim in Patients with Chronic Immune Thrombocytopenia Compared with Administration by a Healthcare Provider: A Single Center Experience

F.J. López Jaime¹, A. Doblas Márquez¹, E. Calavia Aranda¹, I. Sánchez Bazán¹, A. Montaño Brioso¹
Abstract Number: LPB0069

Self-Propelled Hemostatic Powder Safely Achieves and Maintains Hemostasis in a Live Porcine Model of Upper Gastrointestinal Bleeding

N. Ali-Mohamad^1,2, M. Cau^1,2,3, J. Baylis^1,2,3, F. Donnellan^4,5, C. Kastrup^1,2,6
Abstract Number: PB1085

Self-report Instruments for Assessing Adherence to Oral Anticoagulation with Warfarin: A Systematic Review

M.S. Vianna¹, M.F.S. Praxedes², V.E. Araújo³, C.B. Ferreira², W.J.F.N. Sousa⁴, C.C. Viana¹, M.A.P. Martins^4,1
Abstract Number: PB0048

Sensitivity Analysis of a Reduced Model of Thrombosis under Flow: Roles of Factor IX, Factor XI, and γ’-Fibrin

J. Chen¹, S.L. Diamond¹
Abstract Number: PB0921

Sensitivity of ISTH Bleeding Assessment Tool, Bleeding Time and PFA-200 in the Diagnosis of von Willebrand Disease

T. Geevar¹, R. Gautam Dave¹, R. Vijayan¹, A. Samuel¹, S. Singh¹, J. John Mammen¹, S. Chandran Nair¹
Abstract Number: PO137

Sepsis-induced Disseminated Intravascular Coagulation Secondary to COVID-19 and Baricitinib Treatment

U.R. Madera Sanchez¹, K. Cruz Lopez¹, P.J. Colon Ortiz¹, S.A. Gonzalez Goyri¹
Abstract Number: PB0972

Serglycin, an Intragranular Proteoglycan with Many Effects on Platelet Function

H. Chanzu¹, J. Lykins¹, S. Joshi^1,2, M. Chow¹, I. Pokrovskaya³, B. Storrie³, G. Pejler⁴, S.W. Whiteheart^1,2
Abstract Number: PB0211

Serum ACE2 Activity for the Assessment of Disease Prognosis in COVID-19

B. Nagy Jr.¹, Z. Fejes¹, Z. Nagy², R. Sütő³, E. Bíró⁴, G. Bekő⁴, Z. Szentkereszty³, I. Várkonyi², J. Kappelmayer¹, Z. Papp⁵, A. Tóth⁵, M. Fagyas⁵
Abstract Number: PB0835

Serum Complement Levels in Immune Thrombocytopenia: Relation with Clinical Presentation and Treatment Response

S. Pérez -León¹, B. Galmés¹, G. Puguet¹, A. Gutiérrez¹, J.M. Sánchez-Raga¹, M. Canaro-Hyrnik¹
Abstract Number: PB0091

Severe Coagulopathy Induced by Therapeutic Plasma Exchange – A Case Report

S. Lopes¹, R. Pombal¹, L. Vieira¹, R. Neto¹, M.A. Canelas², T. Fonseca², H. Cruz Gomes¹, D. Ferreira¹, P. Castelões²
Abstract Number: PB0724

Severe Congenital Factor XIII-A Deficiency: A Clinical Case

I. Delgado¹, A. Tugues¹, C. Marzo¹, E. Vicente¹, A. Garcia¹, A. Ferrero¹, M.E. Rivero¹, A. Luaña¹, C.E. Chavez¹, M. Teixido¹, A. Ruiz¹, R. Santoja¹, T. Garcia¹
Abstract Number: LPB0122

Severe FXI Deficiency a Pediatric Cohort

A.A. Barg¹, S. Levy¹, E. Avishai¹, A. Dvir¹, N. Kornbrot¹, R. Dardik¹, G. Kenet¹
Abstract Number: PO150

Severe Hemophilia C in a 70-year-old Woman: A Clinical Case

J.A.S. Lopes¹, R.D.M. Almeida², A.C. Gusmão², N.N.S. Magalhães², O.F. Santos¹, A.C.A. Santos³, T.S. Espósito³, L.O.W. Rodrigues⁴, D.O.W. Rodrigues^5,3
Abstract Number: OC 54.2

Severe High Molecular Weight Kininogen (HK) Deficiency: Clinical Characteristics, and KNG1 Mutations in Reported and New Cases

A. Adenaeuer^1,2, H. Rossmann^1,2, A. Trinchero³, S. Krutmann¹, H. Fawzy Nazir^4,5, C. Ambaglio⁶, V. Rocco⁷, F. Häuser², K.J. Lackner^1,2, B. Lämmle^1,8,9, S. Barco^1,10
Abstract Number: PB0234

Severe SARS-CoV-2 Infection is Associated with Impaired Fibrinolysis: A Single Center Study of the Viscoelastic Properties of Blood Clot

S. Hammer¹, H. Häberle², K. Althaus^1,3, T. Bakchoul^1,3
Abstract Number: PB0809

Severe Thrombosis Progression Despite Anticoagulation – Case Report of Antithrombin Deficiency

T. Quaresma¹, A. Parente Freixo¹, M.M. Deveza¹, C. Peixoto¹, J. Amorim¹, A.J Fernandes², M.J. Pereira², Í.R. Oliveira², M.J. Palare³, M. Galvão¹, Á. Beleza¹
Abstract Number: PB0245

Sex Differences in Thromboinflammatory Biomarkers in Patients with COVID-19: Preliminary Findings from a Retrospective, Single Center Study

G.F. Romiti¹, D. Flego¹, R. Marrapodi¹, B. Corica¹, P. Pasculli², S.M. Carli², M.A. Zingaropoli², R. Cangemi¹, V. Raparelli³, M.R. Ciardi², C. Mastroianni², S. Basili¹, L. Stefanini¹
Abstract Number: PB0979

Sex Differences in Thrombosis through Platelet Nitric Oxide Production

M. Godwin^1,1, Z. Hilt², A. Aggarwal¹, S. Shah², J. Gorski², S. Cameron¹
Abstract Number: PB1289

Sex-specific Association of Endogenous PCSK9 with Memory Function in Elderly Subjects at High CV Risk

P. Simeone¹, F. Vadini², R. Tripaldi¹, R. Liani¹, S. Ciotti¹, A. Di Castelnuovo³, F. Cipollone¹, F. Santilli¹
Abstract Number: OC 13.1

Shear-induced Platelet-GPIbα Shedding under Extracorporeal Membrane Oxygenation Promotes Thrombocytopenia Independently from von Willebrand Factor

A. Rauch¹, A. Dupont¹, M. Rosa², C. Casari³, R. Ruez², A. Ung¹, E. Jeanpierre¹, M. Didelot², N. Rousse⁴, P.J Lenting³, M. Moussa⁵, M. Desvages³, F. Vincent⁶, A. Vincentelli⁴, C. Denis³, E. Van Belle⁶, S. Susen¹
Abstract Number: PB0033

Short Peptides in the Regulation Blood Cells Aggregation in Thrombogenesis

M. Golubeva¹
Abstract Number: PB1087

Should We Check the Anticoagulant Activity Of Edoxaban, at Least at the Beginning of the Treatment?

N. García-León¹, M.T. Calderon-López¹, A. Matilla-García¹
Abstract Number: OC 59.2

SIG-009: Novel Encapsulated Non-viral Cell-based Therapy for FVII Deficiency

E. Kelley¹, J. Patel¹, L. Jansen¹, C. Sparages¹, K. Barrett¹, D. Smith¹, E. Makino¹, M. Donovan¹
Abstract Number: PB0224

Significance of D-Dimers in Patients with COVID-19 Having Venous Thromboembolism

B. Moiz¹, H. Alam¹
Abstract Number: PB0020

Single Centre Retrospective Chart Review to Examine the Management of Timing of Anticoagulation and Outcomes in Patients with Cerebral Venous Sinus Thrombosis

G. Mak¹, N. Chan¹, K. Perera¹
Abstract Number: PB0396

Single-cell Level Quantification of Surface Proteins in Platelets and Platelet-derived EVs Using SC-ICP-MS

E. Choi¹, J. Shin¹, S. Park¹, J. Song², T.H. Yoon^1,3,4
Abstract Number: PB0955

Single-cell RNA Sequencing Reveals Features of Hematopoietic Stem and Progenitor Cells in Immune Thrombocytopenia

Y. Liu^1,2, A. Liu^1,2, J. Peng^1,2
Abstract Number: PB1012

Single-cell Transcriptomics of Young and Mature Thrombocytes in Zebrafish

W. Fallatah¹, D. Burks¹, R. Azad¹, P. Jagadeeswaran¹
Abstract Number: LPB0062

Smartphone-based Detection of Platelet Activation in Microfluidic Strips

D. Hodge¹, G. Little¹, A. Edwards¹, C. Jones¹
Abstract Number: PB0517

Soccer Is Popular and Relatively Safe for Children and Young Adults with Hemophilia: Experiences from the Netherlands

O. Versloot¹, J. Blokzijl¹, M. Schuuring², M. Timmer¹, M. Bartels^1,2, W. van Beers¹, K. van Galen¹, I. Kremer Hovinga¹, M. Suijker¹, R. Schutgens¹, P. van der Valk¹, L. van Vulpen¹, J. van der Net², K. Fischer¹
Abstract Number: PB1208

Solitary versus Multiple Subsegmental Pulmonary Emboli: Clinical Characteristics and Outcomes

Y. Hirao-try¹, D. Vlazny¹, D. Houghton¹, A. Casanegra¹, R. Meverden¹, D. Hodge², L. Peterson¹, R. McBane¹, W. Wysokinski¹
Abstract Number: PB0017

Soluble P-selectin is Associated with Increased Risk of Ischemic Stroke in Patients with Atrial Fibrillation on Hemodialysis: Results from the VIVALDI Study

O. Koenigsbruegge¹, S. Schmaldienst², M. Lorenz³, R. Klauser-Braun⁴, I. Pabinger¹, M. Säemann⁵, C. Ay¹
Abstract Number: PB1022

Soluble Triggering Receptor Expressed on Myeloid Cells Like Transcript-1 (sTLT-1) as a Biomarker for Stable Cardiovascular Diseases

Z. Bayron¹, S. Branfield², J. Menendez³, B. Nieves¹, L. Ospina¹, G. Maldonado¹, R. Hunter⁴, A. Valance Washington², L.M Melendez⁵, Y.M Cantres⁶
Abstract Number: OC 16.3

Specialized SPARC-forming Regulatory T Cells Control Venous Blood Clot Degradation

F. Shahneh¹, M. Klein², F. Frauhammer³, H.C. Probst², K. Schäfer⁴, V.K Raker⁵, C. Becker⁵
Abstract Number: PB0779

Specificity and Sensitivity of Pediatric Bleeding Questionnaire (PBQ) in Identifying Patients Requiring further Laboratory Evaluation

T. Yafoshkina¹, D. Florinskiy¹, K. Voronin¹, D. Polokhov¹, A. Poletaev¹, E. Seregina¹, D. Fedorova¹, P. Zharkov¹
Abstract Number: PB0475

Spectrum of F8/F9 Gene Mutations in the PedNet Cohort

V. Labarque¹, M.-E. Mancuso², M. Kartal-Kaess³, R. Ljung⁴, T.S. Mikkelsen⁵, N. Gretenkort Andersson⁶, PedNet Study Group
Abstract Number: OC 21.3

Spectrum of Acquired Platelet Dysfunction with Eosinophilia (APDE) in Tertiary Care Centre in South India

R. Dave¹, T. Geevar¹, J. Mammen¹, M. Kala¹, R. Vijayan¹, S. Singh¹, S. Nair¹
Abstract Number: PB0516

Sports Injuries in Dutch People with Hemophilia: Results of a 12 Months’ Prospective Study

O. Versloot¹, J. Blokzijl¹, M. Schuuring², M. Timmer¹, M. Bartels^1,2, W. van Beers¹, K. van Galen¹, I. Kremer Hovinga¹, R. Schutgens¹, M. Suijker¹, P. van der Valk¹, L. van Vulpen¹, J. van der net², K. Fischer¹
Abstract Number: PB0197

Stability of Oral Anticoagulant Treatment with Vitamin K Antagonists in COVID-19 Patients

E. Camilleri¹, N. van Rein^1,2, F.J.M. van der Meer^3,4, M.C. Nierman⁵, W.M. Lijfering^1,4, S.C. Cannegieter^1,4
Abstract Number: PO106

Stable Fibroatheromatic Plaque Regression Using High-dose Atorvastatin-loaded PESDA Microbubbles-mediated Extracorporeal Shock Wave Sonoporation Therapy

H. Mehrad^1,2, M. Farhoudi³
Abstract Number: PB0631

Standard Prophylactic Regimen Is Three Times and Twice a Week in Hemophilia A and B, Respectively. The Low Dose Tailoring Method of Prophylaxis Has Been Introduced for Patients with Hemophilia

M. Karimi¹, A. Parsa¹, S. Haghpanah¹, F. Sadat Rajaie Ramsheh¹, M. Bordbar¹, N. Bolandparvaz², A. Bazrafshan¹, H. Tavoosi²
Abstract Number: PB0371

Standardization and Automation of Lupus Anticoagulant Diagnosis Using a Complex Automated Algorithm

A. Sáez de Cámara Álvarez¹, M.A. Chang Azancot¹, C. Ponga Palacio¹, G. Mugertza Berastegi¹, U. Canibe Galindez¹, I. Ajuria Morentin¹
Abstract Number: PB1001

Standardization of Platelet-rich Plasma Preparation with Optimal Platelet Function for the Use in Veterinary Regenerative Medicine

S. Kim¹, P.K. Chaudhary¹, S. Kim¹
Abstract Number: PB1282

Standardized Direct Oral Anticoagulants Prescription for the Treatment of Acute Deep Vein Thrombosis in the Emergency Department: A Quality Improvement Initiative

C. Simard¹, L. Poirier-Blanchette¹, T. Cafaro², R. Kerzner³, H. Mantzanis³, M. Koolian²
Abstract Number: PB1271

Statin Use and Recurrence of Venous Thromboembolic Event

H.J. Peroni¹, P.R. Saunero¹, T. Politi¹, F. Holguin¹, J. Wisnivesky¹, M. Burgos¹, M.F. Grande Ratti¹, F.J. Vázquez¹
Abstract Number: PB1148

Statins for Venous Event Reduction in Patients with Venous Thromboembolism: A Multicenter Randomized Controlled Pilot Trial with a Focus on Prevention of Post-thrombotic Syndrome

A. Delluc¹, W. Ghanima², M. Kovacs³, S. Shivakumar⁴, S. Kahn⁵, P.M. Sandset⁶, C. Kearon⁷, M. Rodger⁵
Abstract Number: PB1255

Statins for Venous Event Reduction in Patients with Venous Thromboembolism: A Randomized Controlled Pilot Trial Assessing Feasibility

A. Delluc¹, W. Ghanima², M. Kovacs³, S. Shivakumar⁴, S. Kahn⁵, P.M. Sandset⁶, C. Kearon⁷, M. Rodger⁵
Abstract Number: PB0963

Stimulation of Calpain Activity, Facilitation of Talin Degradation and Shedding of PMPs Exist as the Modalities of Prion-mediated Pathological Effects in Human Platelets

C. Prakash Gaire¹, R. Lala Mallick¹, S. Kumar Karn², R. Thapa³
Abstract Number: PB0404

Strength and Deformability of Fibrin Clots: Biomechanics, Thermodynamics, and Mechanisms of Rupture

V. Tutwiler^1,2, F. Maksudov³, R.I. Litvinov^1,4, J.W. Weisel¹, V. Barsegov³
Abstract Number: LPB0113

Streptococcal Surface Enolase (SEN) Is Overshadowed by Plasminogen-binding Group A Streptococcal M-protein (PAM) for Human Plasminogen Acquisition and Activation

S. Tjia-Fleck¹, Y. Ayinuola¹, Z. Liang¹, V. Ploplis¹, F. Castellino¹
Abstract Number: PB0994

Stripping a Platelet “Sugar Coat” by Shear: Shear-mediated Platelet Desialylation Promotes Reduction in Platelet Count and Increased Microvesiculation

Y. Roka-Moiia¹, S. Miller-Gutierrez¹, J.E. Italiano², M.J. Slepian¹
Abstract Number: PB1018

Structural Characterisation of GPVI in Complex with Nanobody 2 Generates a Domain-swapped GPVI Dimer: Could this Represent a Biologically Active Conformation?

A. Slater¹, Y. Di¹, J. Clark^1,2, N. Jooss^1,3, E. Martin¹, F. Alenazy¹, M. Thomas¹, R. Ariëns⁴, A. Herr⁵, N. Poulter^1,2, J. Emsley^6,2, S. Watson^1,2
Abstract Number: OC 09.4

Structure of the von Willebrand Factor C6 Domain and Effect of Variant p.Gly2705Arg

A. Mojzisch¹, P.-C. Chen², F. Kutzki³, E.-R. Xu⁴, K. Horny², B. Simon², R. Schneppenheim⁵, M.A. Brehm¹, M. Wilmanns⁴, F. Graeter³, J. Hennig²
Abstract Number: PB0879

Structure-based Design of Cyclic Glycoprotein Ibα-derived Peptides Affecting Platelet Interaction with von Willebrand Factor under Shear Conditions

J. Hrdinova^1,2, D.I. Fernández¹, B. Ercig^1,2, B.M. Tullemans¹, D.P. Suylen¹, S.M. Agten¹, K. Jurk³, T.M. Hackeng¹, K. Vanhoorelbeke⁴, J. Voorberg², C.P. Reutelingsperger¹, K. Wichapong¹, J.W.M. Heemskerk¹, G.A.F. Nicolaes¹
Abstract Number: OC 59.4

Studies of LMAN1 and MCFD2 Deficient Cell Lines Provide New Insight into Intracellular Trafficking of FV and FVIII

Y. Zhang¹, B. Emmer², Z. Liu¹, D. Ginsburg², B. Zhang¹
Abstract Number: PB1017

Study of the Affinity of Thrombin towards its Receptors on Platelets

A. Macwan¹, T. Hallström², T. Lindahl¹
Abstract Number: OC 54.4

Studying Factor XII Structure-function Relationships Using Factor XII-HGFA Chimeric Proteins

A. Shamanaev¹, I. Ivanov¹, M. Litvak¹, M.-f. Sun¹, P. Srivastava¹, D. Gailani¹
Abstract Number: PB1173

Subacute Mesenteric Venous Thrombosis Secondary to COVID-19: A Late Thrombotic Complication in a Non-severe Patient

L. Cano Cevallos¹, W. Alemán²
Abstract Number: PB0430

Subcasular Hepatic Hematoma as Thrombolysis Complication. Case Report

D.A. Madrigal-Campos¹, B.d.C. Madrigal-Sanchez²
Abstract Number: PB0699

Subcutaneous Marzeptacog Alfa (Activated) is Effective Treatment of Bleeding in FVII Deficient Rats

T. Knudsen¹, P.B Johansen¹, L. Neuman¹, H. Levy¹, J. Reckless², G.E Blouse¹
Abstract Number: PB1233

Success of Online CME at Improving Knowledge and Confidence around Guideline-directed Management of Cancer-associated Thrombosis

M. Harris¹, J. Spyropoulos¹, M. LaCouture¹, C. Padbury¹, M. Zec Bonomo², C. Capparelli, MBA, CHCP¹
Abstract Number: PB0670

Success of Online CME at Improving Knowledge, Competence, and Confidence around Guideline-directed Management of Oral Anticoagulant-related Urgent Bleeding

M. Harris¹, J. Spyropoulos¹, A. Carothers¹, C. Padbury¹
Abstract Number: PB0687

Successful Experience of Emicizumab Prophylaxis in a Child with Severe Hemophilia A and Inhibitor without Previous Immune Tolerance Induction

R.M. Camelo¹, M. Palis², M.A.F. de Cerqueira², N. Dantas-Silva³, J. Álvares-Teodoro⁴
Abstract Number: PO141

Successful Immune Tolerance Induction with High Dose Simoctocog Alfa in Hemophilia A Adult Patient with High Responder Inhibitor: A Case Report

S.-N. Cheng¹, L.H.-L. Yu², A.J.-H. Lin², L.T. Wang¹
Abstract Number: PO190

Successful Infertility Treatment and Pregnancy Outcome in a Woman with Severe Treatment-refractory ITP

B. Krastev¹, P. Arabadjikova¹, I. Sarbianova¹, G. Grigorov¹, M. Eneva¹, G. Stamenov¹
Abstract Number: PB0725

Successful Pregnancy in a Patient with Factor XIII Deficiency and Recurrent Miscarriages

T. Surapaneni¹, H. Vadlamani¹, M. Sukayogula¹, C. Ranjith², A. Aribandi²
Abstract Number: PB0714

Successful Prophylactic Use of Coagulation Factor X in an Infant Patient in the Home Environment

C. Miller¹, Y. Lantz¹, B. Prosser¹, T. Walton¹
Abstract Number: PB0864

Successful Treatment with Edoxaban in Heparin-induced Thrombocytopenia with Thrombosis: A Case Report

M. Porres-Aguilar¹, F.A. Grimaldo-Gómez², C. Jerjes-Sánchez^3,4, G.A. Altamirano-Solorzano², M.C. Guerrero de León^5,6, R. Izaguirre-Ávila², D. Schuller⁷, R. Prieto⁸, D. Mukherjee⁹
Abstract Number: PB1065

Successfully Treated Pediatric Catastrophic Antiphospholipid Syndrome with Combination of Thrombolytic Agent, Rituximab and Sirolimus

P. Pongphitcha¹, N. Sirachainan¹, Y. Okuno², W. Sasanakul¹, P. Kadegasem¹, D. Songdej¹, A. Chuansumrit¹, S. Vilaiyuk¹
Abstract Number: OC 03.3

Suppression of Fibrinolysis and Hypercoagulability Link Lung Injury and Mortality in Severe COVID-19

L. Olson¹, K. Corey¹, I. Naqvi¹, S. Morrison¹, C. Davis¹, S. Nimjee², L. Que¹, R. Bachelder¹, B. Kraft¹, L. Chen¹, S. Nair¹, J. Levy¹, B. Sullenger¹
Abstract Number: PB0093

Surveillance of Anticoagulation in Patients with Extracorporal Oxygenation Membrane (ECMO)

L.H. Gonzalez-Figueroa¹, F.A. Grimaldo-Gómez¹, X. García-Jiménez¹, V. Anguiano-Alvarez¹, E. Cortina-de la Rosa¹, M.O. Romero-Arroyo¹, G.A. Altamirano-Solorzano¹, G. Rojas-Velazco¹, R.A. Izaguirre-Avila¹
Abstract Number: PB0228

Suspicion of Heparin-induced Thrombocytopenia in COVID-19: Results from a Multi-centric Retrospective Study

N. Gendron¹, A. Lillo-Le Louet¹, W. Amara¹, C. Le Beller¹, R. Chocron¹, L. Calmette², L. Mauge¹, L. Khider¹, D. Veyer¹, B. Planquette¹, B. Rance¹, B. Huynh³, P. Gaussem¹, O. Sanchez¹, J.L. Diehl¹, T. Mirault¹, D.M Smadja¹, D. Helley¹
Abstract Number: PB0823

Switching from Eltrombopag or Romiplostim to Avatrombopag in Immune Thrombocytopenia: A Multicenter Study of U.S. ITP Referral Centers

H. Al-Samkari^1,2, D. Jiang^3,4, T. Gernsheimer^3,4, H. Liebman⁵, S. Lee⁵, M. Wojdyla⁶, M. Vredenburg⁶, A. Cuker⁷
Abstract Number: PB1070

Switching of Oral Anticoagulants in People with Atrial Fibrillation: Insight from Australian General Practices

A. Kefale¹, G. Peterson¹, W. Bezabhe¹, L. Bereznicki¹
Abstract Number: PB1258

Symptomatic versus Incidentally Noted Isolated Subsegmental Pulmonary Embolus Outcomes

D.T Vlazny¹, Y. Hirao-Try¹, D.O Hodge², A.I Casanegra¹, D.E Houghton¹, R.A Meverden¹, L.G Peterson¹, R.D McBane¹, W.E Wysokinski¹
Abstract Number: PB0059

Synthesis and Binding Study of Two Small Heterocyclic Compounds with factor Xa Inhibitory Activity

T. Sengupta¹, S. Karthikeyan², R. Vasanthan³, C Suganthi¹
Abstract Number: LPB0027

Systematic Review on Neonatal Portal Vein Thrombosis

M. Alhaddad¹, N. Radadia¹, A.K. Chan¹, B. Paes¹, S. Williams², M.D Bhatt¹
Abstract Number: LPB0009

Systematic Screening for Pulmonary Embolism in Patients with Suspected Covid-19 in the Emergency Department: A Prospective Cohort Study

I. Luu¹, F. Kroon¹, J. Buijs¹, J. Krdzalic¹, M. de Kruif¹, M. Leers¹, G. Mostard¹, R. Martens¹, R. Mostard¹, D. van Twist¹
Abstract Number: PO163

Systemic Lupus Erythematosus-induced Coagulopathy: A Case Report

G.A. Maia^1,2
Abstract Number: PB0218

Systemic Platelet Exhaustion in Critically-ill Covid-19 Patients

G. Manukjan¹, J. Herrmann², J. Kleiß¹, M. Zeitlhöfler¹, P. Burkard³, P. Kranke², T. Schlesinger², T. Rose¹, F. Simon¹, L. Weiß¹, D. Weismann⁴, C. Lotz², B. Nieswandt¹, P. Meybohm², H. Schulze¹