ISTH 2021 Congress Archives - Page 4 of 91

Abstract Number: PB0925

p.G2752S Severely Affects Dimerization of von Willebrand Factor: An Analysis of Type 3 von Willebrand Disease

S. Okamoto¹, S. Tamura¹, N. Suzuki², K. Odaira¹, Y. Hayakawa¹, A. Suzuki², T. Kanematsu², F. Hayakawa¹, H. Kiyoi¹, T. Kojima³, T. Matsushita²
Abstract Number: PB0876

P2Y₁₂ Receptor Antagonists and Drug-induced Thrombotic Microangiopathies: A Systematic Review of the Primary Evidence

J.C Ho¹, A. Eshaghpour¹, S. Ge², R. Foote¹, M. Crowther³
Abstract Number: PB0427

P2Y12 Inhibitors Administration in Intracranial Stent Procedure, the Usefulness of Monitoring

O. Duranteau¹, M. Drir¹, L. Abdenour¹, V. Degos¹
Abstract Number: OC 51.2

Paediatric D-dimer and Fibrin Degradation Products (FDP) Reference Intervals Using STA® Liatest D-Di Plus and STA® Liatest FDP

N. Letunica¹, V. Karlaftis^2,1, P. Monagle^3,2,1, V. Ignjatovic^2,1.
Abstract Number: PB0912

Palmitate Increases Gene Expression and Stimulated Secretion of von Willebrand Factor in Human Umbilical Vein Endothelial Cells

A.K. Seliga¹, K. Zabłocki¹, J. Bandorowicz-Pikuła¹
Abstract Number: PB1136

Pancreatic-miRaCan-VTE: A R Shiny App to Aid in the Diagnosis of Pancreatic Cancer-associated VTE

J. Oto¹, A.C Larsen², E. Plana^3,1, R. Herranz¹, F. Cana¹, D. Hervás⁴, A. Cañada⁴, Á. Fernández-Pardo¹, S.R Kristensen^5,6, O. Thorlacius-Ussing^2,6, P. Medina¹
Abstract Number: PB1002

Pandrial Platelet Reactivity in Aspirin-treated Individuals: A Comparison between Fasting and Non Fasting On-treatment Platelet Responses

B. Nkambule¹, A.D. Johnson¹
Abstract Number: PB1010

Pathogen-reduced Platelet Concentrates: Novel Concepts to Elucidate the Impact of Different Technologies on Platelet Function

M. Visser¹, W. Schwarz¹, A. Rausch-Mueller¹, S. Volpe¹, A. Hilger¹, U. Salge-Bartels¹
Abstract Number: PB1152

Pathologically Stiff Erythrocytes Can Promote Thrombosis by Impeding Contraction of Blood Clots

V. Tutwiler^1,2, R.I. Litvinov^1,3, A. Protopopova¹, C. Nagaswami¹, C. Villa¹, O. Abdulmalik⁴, D. Siegel¹, J.E. Russell¹, V. Muzykantov¹, W. Lam⁵, D. Myers⁵, J.W. Weisel¹
Abstract Number: PB0619

Patient and Healthcare Professional Perspectives on the Use of a Personal Health Record in Hemophilia Care: A Qualitative Study

M.R Brands¹, J.J Muis², M. Driessens³, F.JM van der Meer⁴, S. Meijer³, M. de Jong³, F. Bellinck⁴, G. Goedhart^4,5, J.G van der Bom⁶, M.H Cnossen⁷, L. Haverman², K. Fijnvandraat^1,8, S.C Gouw^1,6
Abstract Number: PB1265

Patient Satisfaction with Quality of Care from a New Multidisciplinary Thrombosis Service

S. Young^1,2, K.O. Bonsu¹, T. Lee^1,2, H.V Nguyen¹, R. Chitsike^3,4
Abstract Number: PB0641

Patient-centered Digital Health Interventions and their Effects on Health Outcomes: A Systematic Review

M.R Brands¹, S.C Gouw^1,2, M. Beestrum³, M. Driessens⁴, R.M. Cronin⁵, K. Fijnvandraat^1,6, S.M Badawy^3,7
Abstract Number: PB0932

Patient-reported Outcomes in Autosomal Inherited Bleeding Disorders: A Systematic Literature Review

W. Al Arashi¹, M.E. Houwing¹, E.S. van Hoorn², F.W. Leebeek³, J.A. Hazelzet², S.C. Gouw⁴, R.E. Schutgens⁵, S.E. Schols⁶, H.F. Lingsma², M.H. Cnossen¹, The SYMPHONY consortium
Abstract Number: PB0584

Patients with Hemophilia B with Inhibitors in China

X. Dou¹, X. Wang¹, R. Yang¹
Abstract Number: PB0573

Patients with Severe Hemophilia A under Middle-dosed Prophylaxis Benefit from Multi-disciplinary Team Management, an Experience

Z. Shiqiu¹, C. Rong¹, G. Hua¹, L. Jia¹, G. Jing¹, Y. Ming², Z. Hong², Y. Lin², Z. Xin³
Abstract Number: OC 19.2

Patients with VEXAS Syndrome due to Somatic Mutations in UBA1 Present Commonly with Thrombosis

E. Groarke¹, B. Patel¹, A. Dulau-Florea², M. Ferrada³, J. Lotter¹, I. Darden¹, D. Kastner⁴, K. Calvo², P. Grayson³, D. Beck⁴, N. Young¹
Abstract Number: OC 69.4

Pediatric Leukemic Lymphoblasts Produce Hemostatic System Factors: A Novel Contributor to the Hemostatic Imbalance in Pediatric Acute Lymphoblastic Leukemia

G. Aborkhees¹, K. Deitrich¹, L. Mitchell¹
Abstract Number: PB0799

Pediatric Thromboembolism in Chiang Mai University Hospital: A 10-year Review

P. Rahoorak¹, A. Jaengkrajang¹, K. Mankan¹, P. Wongwai¹, P. Pisanuwong¹, K. Fanhchaksai¹, R. Natesirinilkul¹
Abstract Number: PB0068

Performance Evaluation of a New VWF:GPIbM VWF Activity Assay in a Multicenter Study

M. Kahl¹, M. Boehm-Weigert¹, C. Flickinger², N. DeSimone³, D. Dietzen⁴, C. Eby⁴, K. Friedman⁵, K. Kottke-Marchant⁶, T. Ortel⁷, J. Patzke¹, S. Pipe⁸, R. Sarode³, M. Merz¹
Abstract Number: PB0071

Performance Evaluation of the INNOVANCE Anti-Xa Assay for the Quantitative Determination of Apixaban

M. Wilkens¹, A. Doimo¹, A. Wilhelm¹, I. Birschmann², E. Hod³, K. Madlener⁴, M. Merz¹, D. Bussfeld¹, U.-P. Schobel¹
Abstract Number: PB0064

Performance Evaluation of the INNOVANCE Anti-Xa Assay for the Quantitative Determination of Rivaroxaban

D. Pahren¹, M. Wilkens¹, A. Doimo¹, A. Wilhelm¹, I. Birschmann², E. Hod³, K. Madlener⁴, M. Merz¹, D. Bussfeld¹, U.-P. Schobel¹
Abstract Number: OC 08.3

Peri-operative PK-guided Dosing of Desmopressin Combined with FVIII Concentrates in Hemophilia A: Final Results of the DAVID Study

L.G.R. Romano¹, L.M. Schütte¹, R.M. van Hest², K. Meijer³, B.A.P. Laros - van Gorkom⁴, L. Nieuwenhuizen⁵, J. Eikenboom⁶, F.C.J.I. Heubel-Moenen⁷, N. Uitslager⁸, M. Coppens⁹, K. Fijnvandraat^10,11, M.H.E. Driessens¹², S. Polinder¹³, M.H. Cnossen¹⁴, F.W.G. Leebeek¹, R.A.A. Mathôt², M.J.H.A. Kruip¹, On behalf of the SYMPHONY Consortium
Abstract Number: OC 46.1

Peri-procedural Heparin Use in Patients Receiving Edoxaban: Analyses of the Noninterventional Global EMIT (Edoxaban Management in Diagnostic and Therapeutic Procedures) Study

A. Santamaria¹, C. Chen², C. Von Heymann³, T. Vanassche⁴, M. Saxena⁵, J. Jin², M. Unverdorben², P. Colonna⁶
Abstract Number: PB0109

Peridontal Injury Prompts Remote Spleen Activation and the Generation of Spleen Procoagulant Microvesicles in a Periodontitis Murine Model

H. EL Itawi¹, S. Amissi¹, F. Batool², C. Stutz¹, F. El Ghazouani¹, A.B. Chaker¹, A.W. Qureshi¹, F. Moschovaki-Filippidou¹, C. Auger¹, E. Anglès-Cano³, O. Huck², F. Toti⁴
Abstract Number: PB1310

Perinatal Outcome of Normal Pregnant and Pregnant Women Hospitalized for Hypertension (PIH: Pregnancy Induced Hypertension) and Studied for Antiphospholipid Antibodies (aPL) at Time of PIH Onset

B. Grand¹, L.S. Voto¹
Abstract Number: PB0941

Perioperative Management of Patients with von Willebrand Disease Undergoing Surgical Interventions

R. Toenges¹, L. Haack², B. Krammer-Steiner²
Abstract Number: LPB0003

Persistence Pattern to Oral Anticoagulants among Non-valvular Atrial Fibrillation Patients who Switched from Vitamin K Antagonists to Direct Oral Anticoagulants: A Cohort Study

M.M. Toorop¹, Q. Chen¹, M.J. Kruip^2,3, F.J. van der Meer¹, M. Nierman⁴, L. Faber⁵, L. Goede⁶, S.C. Cannegieter¹, W.M. Lijfering¹
Abstract Number: PB0089

Persistently Low Levels of Antithrombin in Trauma Patients Associated with Disseminated Intravascular Coagulation

S. Gando^1,2, T. Wada²
Abstract Number: OC 23.1

Personalized Cancer-associated Thrombosis Risk Assessment: Integration of Plasma Proteomics, Clinical Characteristics, and Machine Learning

J. Zwicker¹, E. Elango¹, R. Patell¹, M. Marchetti², L. Russo², C. Verzeroli², C. Giaccherini², S. Gamba², R. Flaumenhaft¹, C.J Tartari², I. Vlachos¹, A. Falanga^2,3
Abstract Number: PB0859

PF4/Polyanion ELISA-negative Antibodies to PF4 and Non-PF4 Targets Can Mediate Platelet Activation and Cause Heparin-induced Thrombocytopenia (HIT)

B. Singh¹, C. Jones², D.A. Garcia³, N. Leung¹, R.S. Go¹, R. Leger¹, N. Heikal¹, R. Pruthi¹, D. Chen¹, A. Padmanabhan¹
Abstract Number: OC 17.4

Pharmacodynamics of Bolus with and without Infusion of Cangrelor in Healthy Volunteers: A Dose-finding, Open-label, Pilot Trial

G. Gelbenegger¹, J. Grafeneder², G.M. Gager³, J.M. Siller-Matula³, M. Schwameis², B. Jilma¹, C. Schörgenhofer¹
Abstract Number: OC 24.3

Pharmacokinetic Analysis of fVIII Exposure Identifies an Immunogenicity Threshold after AAV-FVIII Gene Therapy in a Murine Hemophilia A Model

T.S. Lundgren¹, H.T. Spencer^1,2, C.B. Doering^1,2
Abstract Number: PB0568

Pharmacokinetic-guided Prophylaxis Improved Clinical Outcomes in 46 Pediatric Patients with Severe Hemophilia A

H. Kun¹, L. Gang¹, Z. Yingzi¹, W. Xinyi¹, C. Zhenping¹, W. Runhui¹
Abstract Number: PB0077

Pharmacokinetics and Pharmacodynamics of Abelacimab (MAA868), a Novel Dual Inhibitor of Factor XI and Factor XIa

B.A. Yi¹, D. Freedholm¹, N. Widener¹, X. Wang², E. Simard², L. Galitz³, N.M. Al-Saady⁴, N.E. Lepor⁵, M. Lovern², D. Bloomfield¹
Abstract Number: PB0614

Pharmacokinetics-adjusted Dosing of Rurioctocog Alfa Pegol (Adynovi) in Adult Patients with Haemophilia A

J. Treliński¹, K. Chojnowski¹, M. Robak¹, A. Mital², E. Zarzycka², M. Bober³, J. Dziamska³, T. Woźny³, D. Urbaniak-Kujda⁴, I. Prajs⁴, M. Podolak-Dawidziak⁴
Abstract Number: PB0917

Pharmacokinetics/Pharmacodynamics (PK/PD) of Recombinant von Willebrand Factor (Vonicog Alfa) in Adult Patients with von Willebrand Disease (VWD) during Prophylactic Treatment

A. Iorio¹, F. Leebeek², S. Susen³, A. Shapiro⁴, G. Özen⁵, B. Mellgård⁵, Y. Wang⁶
Abstract Number: PB1224

Pharmacologic Profiles of Direct Oral Anticoagulants in Patients Receiving Rituximab-CHOP Chemotherapy

T. Punnachet¹, T. R. Cressey¹, P. Apiwatnakorn², A. Koonarat³, L. Norasetthada¹, A. Tantiworawit¹, E. Rattaritamrong¹, T. Rattanathammethee¹, S. Huntrakool¹, P. Piriyakhuntorn¹, C. Chai-Adisaksopha¹
Abstract Number: PB0958

Pharmacological Characterization of eNOS-based Megakaryocyte Subpopulations and its Implications for their Platelet Progeny

A. Asgari¹, P. Jurasz^1,2
Abstract Number: OC 71.1

Pharmacological Targeting of Coagulation Factor XI Mitigates the Development of Experimental Atherosclerosis in Low-density Lipoprotein Receptor-deficient Mice

A. Ngo¹, K. Jordan¹, P. Mueller¹, M. Hagen¹, S. Reitsma¹, C. Puy¹, A. Revenko², C. Lorentz¹, E. Tucker¹, Q. Cheng³, M. Hinds¹, S. Fazio¹, B. Monia², D. Gailani³, A. Gruber¹, H. Tavori¹, O. McCarty¹
Abstract Number: PO174

Pharmacological Venous Thromboembolism Prophylaxis in an Internal Medicine Ward: Cross-sectional Observational Study

G. Durao-Carvalho¹, A. Canoso¹, J. Louro¹, R. Amorim¹
Abstract Number: LPB0128

Phase 3 Trial Results: Prophylaxis with Recombinant von Willebrand Factor in Patients with Severe von Willebrand Disease

F.WG Leebeek¹, F. Peyvandi², M. Escobar³, A. Tiede⁴, G. Castaman⁵, J. Gu⁶, B. Mellgård⁷, B. Ewenstein⁷, G. Özen⁷
Abstract Number: OC 72.2

Phase I/II Ongoing Study of Rilzabrutinib, an Oral Bruton Tyrosine Kinase Inhibitor, in Immune Thrombocytopenia: Extended Follow-up and Long-term Analyses with Optimal Dose

D.J. Kuter¹, N. Tzvetkov², M. Efraim³, Z. Kaplan⁴, J. Mayer⁵, P. Choi⁶, A.J.G. Jansen⁷, V. McDonald⁸, R. Baker⁹, R. Bird¹⁰, M. Garg¹¹, J. Gumulec¹², M. Kostal¹³, T. Gernsheimer¹⁴, W. Ghanima¹⁵, O. Bandman¹⁶, P. Arora¹⁶, Q. Tran¹⁶, H. Guo¹⁷, N. Cooper¹⁸
Abstract Number: OC 67.2

Phase I/II Trial of SPK-8011: Stable and Durable FVIII Expression After AAV Gene Transfer for Hemophilia A

L.A. George^1,2, P.E. Monahan³, M.E. Eyster⁴, S.K. Sullivan⁵, M.V. Ragni⁶, S.E. Croteau^7,8, J. Rasko^9,10, M. Recht¹¹, B.J. Samelson-Jones^1,12, A. MacDougall¹³, K. Jaworski¹³, R. Noble¹³, M. Curran³, K. Kuranda¹³, F. Mingozzi¹³, K.Z. Reape³, X.M. Anguela³, K.A. High³
Abstract Number: PB0700

Phenotype-Genotype Relationship in Patients with Hereditary FXI Deficiency

C. Albayrak¹, D. Albayrak², H. Gürkan³, S. Demir³
Abstract Number: PB0761

Phenotypic Changes in Platelets during Measles Virus Infection of Rhesus Macaques (Macaca Mulatta)

S. Guerrero-Martin^1,2, E. Shirk¹, J. Brockhurst^1,3, N. Peart Akindele^1,3, J. Villano¹, D. Griffin^1,3, K. Metcalf Pate^2,1
Abstract Number: PB0023

Photodynamic Therapy with 5- Aminolevulinic Acid and B-mode Ultrasound-guided Catheter-based Low-level Red Laser Results in Cerebrovascular Neointimal Hyperplasia Regression

H. Mehrad^1,2, A. Sultan- Qurraie³
Abstract Number: PB0187

Physicians’ Knowledge and Management Practices of COVID-19 Coagulopathies in Pregnancy

S. Jevtic¹, A.K. Malinowski^2,3, M. Othman^4,5, R. Abdul Kadir⁶
Abstract Number: PB0987

PI4P and PI(4,5)P2 Immunofluorescence Staining Optimization in Human Platelets

A. Bura¹, I. Đurić¹, S. Čabrijan¹, A. Jurak Begonja¹
Abstract Number: OC 09.1

Piggyback Knockdown Screen of Glycosyltransferases in Zebrafish: Identification of Novel Regulators of von Willebrand Factor Levels

N. Iyer¹, A. Al Qaryoute¹, P. Jagadeeswaran¹
Abstract Number: PB0851

PK/PD Modeling and Simulations Highlight the Importance of the Intravenous Loading Dose and Daily Dosing Regimen with Caplacizumab for Patients with aTTP

T. Sou¹, F. Callewaert², R. de Passos Sousa³, M.L. Sargentini-Maier¹
Abstract Number: PB0840

Plasma BioID of ADAMTS13

H. Madarati¹, K. Singh¹, T. Sparring¹, C. Kretz¹
Abstract Number: PB1090

Plasma Biomarkers for Predicting Risk of Venous Thromboembolism (VTE) in Ambulatory Cancer Patients Receiving Chemotherapy

D. Roy¹, T.F. Wang^2,3, M. Carrier^2,3, E. Mollanji^2,3, P. Liu⁴, P. Wells^2,3
Abstract Number: PB0733

Plasma D-dimer and Fibrinogen Levels Correlates with Tumour Size and Disease Progression in Nigerian Breast Cancer Patients

O. Izuegbuna¹, O. Agodirin², H. Olawumi², S. Olatoke²
Abstract Number: PB0939

Plasma-derived VWF/FVIII Concentrate (wilate^®) for Haemostasis in Women with VWD during Childbirth

A. Iorio¹, A. Srivastava², P. James³, A. Ma⁴
Abstract Number: PB0347

Plasmatic Rivaroxaban Concentration Estimation through the Measurement of Anti Xa Activity Calibrated with Heparin Calibrators Using 3 Reactive/Instrument Systems: Multicenter Study

M. Martinuzzo^1,2, C. Duboscq³, M. Arias⁴, M.S. López^1,2, E.S Viñuales^5,2, D. Mezzarobba⁵, V. Privitera⁵, D. Penchasky⁵, F. Chuliber⁵, J. Ceresetto³, M. Gurfinkiel⁴, L. Barrera^1,2
Abstract Number: OC 26.4

Plasmin-responsive Procoagulant Synthetic Platelets for Fibrin Clot Stabilization in Hemorrhage Control

A. Sen Gupta¹, U. Didar Singh Sekhon¹, N. Luc¹, A. Girish¹, M. de la Fuente¹, M. Nieman¹
Abstract Number: OC 41.3

Plasminogen, but Not Fibrinogen, Promotes Pancreatic Ductal Adenocarcinoma Tumor Growth and Metastasis

Y. Yang¹, S. Abrahams¹, K. Davey¹, A. Revenko², M. Fishel³, A. Wolberg¹, M. Flick¹
Abstract Number: PB1061

Plasmocytoid Dendritic Cells Activity in Asymptomatic Antiphospholipid Carriers and in Primary and Secondary Antiphospholipid Syndrome with Thrombosis

A.P. Rosa dos Santos¹, B. Cardoso Jacintho², C. de Oliveira Vaz², G. Lisiane Tripiquia Vechiatto Mesquita¹, J.D. Oliveira², J. Annichino-Bizzacchi³, S. Appenzeller⁴, B. Moraes Mazetto⁵, F. A. Orsi⁶
Abstract Number: PB0822

Platelet Activation and Function in Adult Patients with Primary Immune Thrombocytopenia

J. Machacek¹, L. Buresch¹, D. Mehic¹, T. Schramm¹, M. Fillitz², B. Dixer², T. Flasch¹, T. Anderle¹, A. Rath¹, C. Ay¹, I. Pabinger¹, J. Gebhart¹
Abstract Number: LPB0141

Platelet Activation and Platelet Indices as Markers for Disease Progression in Women with Breast Cancer

Y. Tera^1,2, H. Azzam¹, N. Abousamra¹, M. Zaki³, A. Eltantawy⁴, M. Awad⁴, H. Ghoneim¹, M. Othman²
Abstract Number: OC 70.4

Platelet Activation via PI3K/AKT Signaling Pathway in COVID-19

L. Pelzl¹, A. Singh¹, J. Funk¹, A. Witzemann¹, J. Zlamal¹, I. Marini¹, K. Weich^1,2, W. Abou-Khalel², S. Hammer², G. Uzun², K. Althaus^1,2, T. Bakchoul^1,2
Abstract Number: PB0978

Platelet Activity and Platelet-induced Endothelial Inflammatory Pathways in Treated HIV Is Lowered by Clopidogrel: A Randomized Control Trial

T. Schwartz¹, E. Maracantoni¹, N. Allen¹, M. Cambria¹, R. Dann¹, M. Garshick¹, J.S. Berger¹
Abstract Number: PB1060

Platelet Activity from Antiphospholipid Syndrome (APS) Patients is Enhanced: Possible Role of the ADP Signaling Pathway

G. Leonardi¹, C.H. Lescano¹, A.P.R. Dos Santos², B.C. Jacinto², B.M. Mazetto², F.A. Orsi^3,4, F.Z. Mónica¹
Abstract Number: PB0817

Platelet Apoptosis and Autophagy in Pediatric Immune Thrombocytopenia: New Mechanistic Insights

T. Stein¹, R. Hinselmann¹, C. Gowin¹, D. Greber¹, S. Shllaku¹, N. Gölz¹, M. Schmugge¹, F.D. Franzoso¹
Abstract Number: OC 11.2

Platelet Binding to Polymerizing Fibrin is Avidity-driven and Requires Activated αIIbβ3

C.L. Buitrago¹, O. Bentur¹, B. Coller¹
Abstract Number: OC 52.3

Platelet Chemokines and Integrins Antagonistically Steer Neutrophil Activation in Arterial Thrombus Formation

C. Schönichen^1,2, M. Nagy¹, S.LN Brouns¹, S. Montague³, F. Ní Ainle⁴, K. Knoops⁵, R.R Koenen¹, O. Soehnlein⁶, S.P Watson⁷, J.WM Heemskerk¹
Abstract Number: PB0208

Platelet Dynamics in Hospitalized Patients with SARS CoV-2 Infection

V.E. Delgado Pinos¹, R.M. Martín Rojas¹, C. Pascual Izquierdo^1,2, J.L. Díez Martín^1,2,3, G. Perez Rus^1,3
Abstract Number: PB0892

Platelet Dysfunction in Noonan Syndrome

S. Sorrentino¹, I. Lazzareschi^2,3, M. Capurso², R. Onesimo², C. Leone², A. Romano², M. Mele², G. Zampino^2,3, E. De Candia¹
Abstract Number: OC 15.1

Platelet Factor 4 (PF4) Enhances in vitro Neutrophil Extracellular Traps (NET) Capture of Coronaviruses: Clinical and Therapeutic Implications

M. Ishizuka¹, B. Estevez¹, A. Sarkar^1,1, M.A. kowalska¹, L. Rauova¹, M. Poncz¹, K. Gollomp¹
Abstract Number: OC 40.3

Platelet Fibrinogen Receptor Expression and Platelet Function Decreases as Duration of ECMO Increases in Paediatric Veno-arterial ECMO Patients

S. Van Den Helm¹, H.P. Yaw¹, N. Letunica¹, R. Barton^1,2,3, F. Newall^1,2,3, S. Horton^2,3, G. MacLaren^1,2,3,4, R. Chiletti^1,2, A. Johansen^1,2, D. Best^1,2, J. McKittrick², W. Butt^1,2,3, Y. d'Udekem^1,3,5, M. Linden⁶, P. Monagle^1,2,3, V. Ignjatovic^1,3
Abstract Number: LPB0073

Platelet Function Is Inhibited by Dengue Virus

MA. Mosso-Pani¹, M.I. Salazar², N. Corona-de-la-Peña³
Abstract Number: PO160

Platelet Hyperaggregability and Migraine Headache – A Single Centre Experience

M. Brunclikova¹, L. Stanciakova¹, J. Ivankova¹, M. Skerenova², T. Simurda¹, M. Dobrotova¹, P. Holly¹, I. Skornova¹, P. Kubisz¹, J. Stasko¹
Abstract Number: PB0764

Platelet Involvement and its Association with Mortality in COVID-19 Patients at a Safety-net Hospital

L.F. Gonzalez-Mosquera¹, S. Gomez-Paz¹, E. Lam¹, D. Cardenas-Maldonado¹, J. Fogel², V. Adi¹, S. Rubinstein¹
Abstract Number: PB1048

Platelet microRNA Release in the Context of Agonist-stimulation and Thrombosis

T.L. Krammer¹, S. Zeibig², H.-P. Holthoff², M. Hackl¹
Abstract Number: OC 41.1

Platelet microRNAs Inhibit Primary Tumor Growth via Broad Modulation of Tumor Cell mRNA Expression in Ectopic Pancreatic Cancer in Mice

J.G. Wurtzel¹, S. Lazar¹, I. Astsaturov², A.S. Weyrich³, J.W. Rowley³, L. Goldfinger¹
Abstract Number: OC 10.3

Platelet Proteome and Variability in the Responsiveness to Low-dose Aspirin in Patients with Cardiovascular Disease

S. Ciotti^1,2, P.G. Simeone^1,2, R. Liani^1,2, R. Tripaldi^1,2, A. Boccatonda^3,2, D. D'Ardes^3,2, A. Recchiuti⁴, M. Romano⁴, F. Santilli^1,2,3
Abstract Number: OC 35.1

Platelet TFPIα Dampens Prothrombotic and Fibrotic Responses to Radiation Injury in Mouse Heart

S. Maroney¹, N. Martinez¹, J. Peterson¹, J. Lincoln², A. Mast¹
Abstract Number: LPB0074

Platelet Transfusion Does Not Prevent Experimental Polymicrobial-induced Septic Shock in Mice

Y. Rabouel¹, S. Magnenat¹, F. Lefebvre¹, X. Delabranche², C. Gachet¹, B. Hechler¹
Abstract Number: PB0011

Platelet-derived Let-7e is an Independent Predictor of Long-term All-cause Mortality in Patients with Type 2 Diabetes Mellitus

C. Eyileten¹, J. Pordzik¹, D. Jakubik¹, P. Czajka¹, M. Wolska¹, J. Jarosz-Popek^1,2, A. Fitas¹, A. Nowak¹, S. De Rosa³, A. Gąsecka⁴, A. Kapłon-Cieślicka⁴, J.M. Siller-Matula⁵, M. Postuła¹
Abstract Number: PB0021

Platelet-derived microRNAs Are Increased after Transcatheter Aortic Valve Implantation and May Predict Adverse Outcomes in Patients with Heart Failure

C. Eyileten¹, A. Fitas¹, J. Jarosz-Popek^1,2, T. Adem¹, D. Jakubik¹, M. Wolska¹, A. Nowak¹, P. Czajka¹, M. Postuła¹, A. Gąsecka³
Abstract Number: LPB0135

Platelet-rich Neutrophil-platelet Micro-emboli Contribute to Cigarette Smoke-induced Influenza Severity

T.W. Kaminski¹, T. Brzoska¹, X. Li¹, R. Vats¹, R. Dubey¹, K. Nickolich¹, K. Robinson¹, T. Nyunoya¹, P. Sundd¹
Abstract Number: LPB0129

Platelet-specific Deletion of Acetyl-CoA Carboxylase 1 Decreases Phospholipid Content and Impairs Platelet Functions

M. Octave¹, L. Pirotton¹, A. Ginion¹, V. Robaux¹, S. Lepropre¹, S. Kautbally¹, Y. Senis², Z. nagy³, J. Ambroise⁴, B. Guigas⁵, M. Giera⁵, L. Bertrand¹, C. Beauloye¹, S. Horman¹
Abstract Number: PB0253

Platelets and Neutrophil Extracellular Traps (NETs) in Immunothrombosis Progression at COVID-19

I. Vasilenko^1,2, A. Gur’ev¹, D. Kassina¹, V. Metelin^3,2, V. Schelkova¹
Abstract Number: PB0319

Platelets Collected from Blood Diversion Pouches Are an Appropriate Alternative for Functional and Bioenergetic Analyses

O. Esparza¹, G. Hernandez¹, M. Kelher¹, K. Kelly², C. Silliman¹, L. Dumont², P. Davizon-Castillo¹
Abstract Number: PB0201

Platelets from Donors of Convalescent Plasma after Mild COVID-19 Do Not Express Procoagulant Phenotype

G. Uzun¹, L. Pelzl², W. Abou-Khalel², A. Singh², S. Nowak-Harnau¹, K. Althaus^1,2, T. Bakchoul^1,2
Abstract Number: OC 31.3

Platelets from Patients with MYH9 Related Disorders Are Mechanically Stiffer

L. Sachs¹, J. Baumann², J. Wesche¹, P. Nestler³, C. Zaninetti¹, A. Greinacher¹, M. Bender², O. Otto³, R. Palankar¹
Abstract Number: PB0155

Platelets of COVID-19 Patients Are Refractory due to Thrombin Receptor Desensitizing in the Bloodstream

A. Martyanov^1,2,3, A.E. Boldova², M.G. Stepanyan^4,2, O.I. An^5,2, S.V. Tsarenko⁶, S.A. Rumyantsev⁷, S.S. Karamzin², M.A. Panteleev^2,1,4, A.G. Rumyantsev¹, F.I. Ataullakhanov^2,1,4, A.N. Sveshnikova^4,1,2,5
Abstract Number: OC 74.4

Platelets Preferentially Bind Senescent Red Blood Cells and Regulate in their Clearance

B. McMorran¹, D. Ningtyas¹, F. Leitner², M. Sawbridge¹, J. Lee³, M. Rug³
Abstract Number: PB0747

Platelets Promoted Malignancy Involving Exosomal HMGB1

J.-D. Wang¹, C.-J. Chen¹, S.-L. Liao¹, S.-W. Huang²
Abstract Number: PB0759

Platelets Show a Distinct Response in a Controlled Human Malaria Infection (CHMI) Model

A. Singh¹, A. Witzemann¹, L. Pelzl¹, I. Marini¹, F. Rigoni¹, J. Zlamal¹, A. Kreidenweiss², B. Mordmüller², P. Kremsner², T. Bakchoul^1,3
Abstract Number: OC 58.4

Platelets Stimulate Programmed Death-ligand 1 Expression by Cancer Cells: Inhibition by Anti-platelet Drugs

A. Asgari¹, G. Lesyk¹, E. Poitras², N. Govindasamy³, K. Terry², R. To¹, V. Back¹, J. Rudzinski³, J. Lewis³, P. Jurasz^1,2
Abstract Number: OC 61.1

Pleiotropic Role of miR-146a in Driving Metabolism Reprogramming Causes Platelet Hyperreactivity and Thrombosis

S. Águila¹, A.B Arroyo¹, J.C Cañaveras-García², M.P Fernández-Pérez¹, A.M De los Reyes-García¹, N. García-Barberá¹, L. Reguilón-Gallego¹, L. Zapata-Martínez¹, I. Ruiz-Lorente¹, V. Vicente³, J. Rivera³, A. Lahoz², M.P. Gratacap⁴, R. González-Conejero¹, C. Martínez¹
Abstract Number: OC 01.2

Podocyte Tissue Factor Suppresses Spontaneous Sterile Renal Inflammation

J. Manoharan¹, R. Rana¹, D. Gupta¹, A. Elwakiel¹, K. Shahzad¹, B. Isermann¹
Abstract Number: OC 30.1

Podoplanin and Tissue Factor Cooperate in Triggering Microthrombosis in Experimental Glioblastoma and Are Released to Systemic Circulation as Cargo of Extracellular Vesicles

N. Tawil^1,2, R. Bassawon¹, B. Meehan², L. Montermini², A. Nehme¹, D. Choi^1,2, L. Adnani^1,2, C. Spinelli^1,2, N. Mackman³, Y. Riazalhosseini¹, H. Najafabadi¹, J. Rak^1,2
Abstract Number: PB0042

Polycationic Molecules Towards the Inhibition of Procoagulant and Antifibrinolytic Properties of Nucleic Acids

S. Vappala^1,2,3, M.T. Kalathottukaren^1,2,3, C. La^1,2,4, S. Abbina^1,2,3, L. Abraham^1,5, I. Constantinescu^1,2,3, E. M. Conway^1,2,6, C. A Haynes^1,2,7, J. N. Kizhakkedathu^1,2,3,8
Abstract Number: PB1038

Ponatinib Induces Vasculitis with Immune Cells Expressing Coagulation Factors FV & FVIII

P. Zeng¹, A. Merkulova¹, E. Chan¹, A.H. Schmaier¹
Abstract Number: PB0976

Ponatinib Inhibits Collagen Induced Platelet Aggregation and Coated-platelet Formation in Human Platelets

I. Beke Debreceni¹, G. Mezei², P. Batár², L. Kozma³, J. Kappelmayer¹
Abstract Number: PB0692

Population Parmacokinetics of rFXIII (Catridecacog) and Clinical Outcomes of Prophylaxis in an Italian Population of Patients with Factor XIII Deficiency

E. Zanon¹, S. Pasca¹, G. Sottilotta², A.C. Molinari³, L. Banov³, A. Ferretti⁴, P. Di Gregorio⁵, B. Pollio⁶, S.M. Siboni⁷, R. Palla⁷, F. Peyvandi⁷, M. Pizzuti⁸, L.D. Notarangelo⁹, P. Cojutti¹⁰, C. Biasoli¹¹, P. Simioni¹, F. Pea¹⁰
Abstract Number: PB0580

Population Pharmacokinetic Modeling of Factor Concentrates in Hemophilia: A Detailed, Clinical Overview and Evaluation of Best Practice

M.H. Goedhart¹, L.H. Bukkems², C.M. Zwaan¹, R.A. Mathot², M.H. Cnossen¹, for the OPTI-CLOT study group and SYMPHONY consortium.
Abstract Number: LPB0059

Population Pharmacokinetics of Anti-Xa Levels in COVID-19 ICU Patients Receiving Prophylaxis for Thrombo-embolic Events Using Nadroparin

L.G.R. Romano¹, H. Endeman², N.G.M. Hunfeld^2,3, T. Preijers³
Abstract Number: OC 20.4

Portal Vein Thrombosis(PVT) in Neonates and Children: A Ten-year Prospective Registry of a Tertiary Care Single-centre in Argentina

C. Cervio¹, M. Hepner¹, B. Bianco¹, G. Pieroni¹, E. Annetta¹, J.P. Frontroth¹, G. Sciuccati¹
Abstract Number: PB0185

Post Hospital Discharge Thrombosis in Patients with COVID-19

P. Li¹, S. Kaatz², W. Zhao³, K. Latack¹, L. Schultz¹, L. Poisson¹
Abstract Number: PB0527

Postoperative Bleeding Complications in Patients with Hemophilia Undergoing Major Orthopedic Surgery: A Prospective, Multicenter Observational Study

T.W. Buckner¹, B. Kleiboer², M. Layer², L. Cafuir³, A. Cuker⁴, M. Escobar⁵, M.E. Eyster⁶, E. Kraut⁷, A.D. Leavitt⁸, S.R. Lentz⁹, D. Quon¹⁰, M. Ragni¹¹, D. Thornhill¹, M. Wang¹, N.S. Key²
Abstract Number: OC 62.4

Postpartum Hemorrhage in Women with von Willebrand Disease and Carriers of Hemophilia: A Retrospective Analysis

M.C. Punt¹, F. van Leusden¹, K.W.M. Bloemenkamp², M. Coppens³, M.H.E. Driessens⁴, S. Haitjema⁵, F.C. Heubel-Moenen^6,7, A.T. Lely², A.B. Mäkelburg⁸, L. Nieuwenhuizen^6,9, W.W. van Solinge⁵, J.L. Saes^10,6, S.E.M. Schols^10,6, R.E.G. Schutgens¹, J. Eikenboom¹¹, M.J. Kruip¹², K.P.M. van Galen¹
Abstract Number: PB0587

Posttraumatic Stress Disorder and Posttraumatic Stress Symptoms Among Adults with Hemophilia A and B

A. Stahl¹, K. Barnett², A. Wilson³, H.S. Park¹, M. Geary¹, S. Ren⁴, D. Neuberg⁴, A. Parnes¹
Abstract Number: PB0251

Potential Markers to Predict Mortality in COVID-19

C. Klapheke¹, H. McRae¹, T. Love¹, M. Refaai¹
Abstract Number: LPB0021

Practical Application of FIX-Padua Field Study Results Enables a Comparison of FIX:C Results Across AAV Gene Therapy Trials Independent of FIX:C Assay Reported

E. Shehu¹, J.H. Foley¹, E. Gray², A. Riddell^3,4, A. Goodale¹, I-M. Yu¹, J. Little¹, D. Shattock¹, S. Kitchen⁵, P. Chowdary^3,4, A. Nathwani^3,4, R. Corbau¹
Abstract Number: PB1281

Practical Considerations for Treatment of Left Ventricular Thrombus with Direct-acting Oral Anticoagulants

R. Brazilek¹, H. Bortz¹, C. Corallo¹, J. McFadyen¹
Abstract Number: LPB0056

Pre-admission Anticoagulant Therapy and Mortality in Hospitalized COVID-19 Patients: A Covid Predict Retrospective Cohort Study

T.F. van Haaps¹, D. Collard¹, S. Middeldorp¹, M. Coppens¹, M.D. de Kruif², H. ten Cate³, P.R. Tuinman⁴, R.A. Douma⁵, M.C. Muller⁶, A.C. Reidinga⁷, M.A. Heuvelmans⁸, M. Oudkerk⁸, F.H. van Osch⁹, J.P. van den Bergh⁹, A. Maas⁹, N. Gritters¹⁰, M. Ten Wolde⁵, N.P. Juffermans¹¹, N. van Es¹, on behalf of the Dutch COVID & Thrombosis Coalition
Abstract Number: PB0559

Predicted FVIII Consumption of BAY 94-9027 Compared with Standard- and Extended-half-Life FVIII Products in Patients with Severe Hemophilia A

A. Solms¹, A. Shah², E. Berntorp³, A. Tiede⁴, A. Iorio⁵, A. Bröker⁶, M.E. Mancuso⁷
Abstract Number: PB0470

Predicting the Duration of Recombinant Factor VIIa Effect on Tail Bleeding by the Thrombin Generation Assay in Hemophilia A Mice

S. Surov^1,2, M. Ovanesov¹
Abstract Number: OC 57.3

Prediction of Mortality in Patients with Recently Diagnosed Venous Thromboembolism: The GARFIELD-VTE Mortality Risk Model

A.E. Farjat¹, K.A. Fox², A.G. Turpie³, S.Z. Goldhaber⁴, H. Bounameaux⁵, P. Prandoni⁶, J.I. Weitz⁷, F. Dalgaard⁸, P. Angchaisuksiri⁹, S. Haas¹⁰, S. Schellong¹¹, W. Ageno¹², S. Goto¹³, E. Panchenko¹⁴, C.-E. Chiang¹⁵, C. Jerjes Sanchez Diaz¹⁶, J. Muntaner¹⁷, P. Verhamme¹⁸, E. Tse¹⁹, A.K. Kakkar^1,20
Abstract Number: PB1125

Prediction of Venous Thromboembolism among Ambulatory Cancer Patients with Gastrointestinal Malignancies – A Retrospective Analysis

K. Pavithran¹, H. Jayamohanan¹, S. Soman¹
Abstract Number: PB1186

Predictors for Prognosis in Patients with Nonfatal Pulmonary Embolism in COVID-19 Pandemic

N. Diaconu¹, T. Cuzor¹, D. Lupu¹, A. Grosu¹, L. Caldare¹
Abstract Number: OC 44.2

Predictors of Lupus Anticoagulant Test Variability over Time and its Associations with Future Thrombotic Events: Results from the Vienna Lupus Anticoagulant and Thrombosis Study (LATS)

M. Colling^1,2, F. Posch^1,3, S. Koder¹, C. Ay¹, I. Pabinger¹, J. Gebhart¹
Abstract Number: PB1277

Predictors of Recurrence of Venous Thromboembolic Disease after Suspension of Anticoagulation

M.L. Posadas-Martinez¹, F. Torres Gómez¹, C. Juana², M.F. Grande Ratti¹, M. Burgos¹, D. Mezzarobba¹, N. Schutz¹, J. Ruberto¹, M.F. Dovasio¹, M. Martinuzzo¹, F. Gonzalez Bernaldo De Quiros¹, F.J. Vazquez¹, D.H. Giunta¹
Abstract Number: LPB0091

Predictors of the Development of the Post-thrombotic Syndrome: A Sub-analysis of the ATTRACT Trial

F. Rinfret^1,2, C.-S. Gu³, S. Vedantham⁴, S. Kahn^2,1
Abstract Number: PB1300

Preeclampsia and Inflammatory Lipid Mediators: A Longitudinal Study

L. Perucci¹, K. Pinto¹, S. Silva¹, E. Lage², P. Teixeira², A. Barbosa², P. Alpoim², L. Sousa², L. Dusse², A. Talvani¹
Abstract Number: PB0658

Preferences of People with Hemophilia A and B for Treatments Including Gene Therapies in the US: A Discrete Choice Experiment

M. Witkop¹, G. Morgan², J. O'Hara^2,3, M. Recht^4,5, T.W. Buckner⁶, D. Nugent⁷, R. Curtis⁸, B. O’Mahony^9,10, M.W. Skinner^11,12, B. Mulhern¹³, M. Cawson², T. Ali¹⁴, E. Sawyer¹⁴, N.(. Li¹⁴
Abstract Number: PB1298

Pregnancy and Heparin: Peripartum Management. Experience of Two Centers in Argentina

S. Molnar¹, C. Gumpel²
Abstract Number: OC 34.4

Pregnancy from in vitro Fertilization is Associated with Increase in Risk of Venous Thromboembolism when Compared to Normal Pregnancy: A Systematic Review and Meta-analysis

R. Dewangga¹, K. Winston²
Abstract Number: PB0805

Preliminary Results of the Adventh-pediatric Registry in a Southeastern Brazilian City

T. Mello¹, S. Rigatto¹, R. Vilela¹, M. Veríssimo², T. Rodrigues¹, G. Nunes¹, S. Huber¹, V. Pinheiro¹, J. Pires², S. Montalvão¹, J. Annichino-Bizzacchi¹
Abstract Number: PB1194

Premature Mortality Burden Related to Pulmonary Embolism in Cuba

K. Valdés-Díaz¹, H. Hernández-Negrín¹
Abstract Number: OC 75.1

Prenatal Therapy with Placental Cells Transduced with an Engineered fVIII Transgene Results in Curative fVIII Plasma Levels for 3 Years after Birth, Without Immune- or Toxicity-related Adverse Events

M. Rodriguez¹, B. Trevisan¹, s. george¹, R. Ramamurthy¹, J. Shields², D. Schwahn³, J. Figueroa⁴, D. Meares⁴, J. Owen⁴, M. Gautreaux⁴, A. Atala¹, C. Doering², HT. Spencer², C. Porada¹, G. Almeida-Porada¹
Abstract Number: PB0096

Preoperative Hemorrhagic Risk Assessment: Knowledge, Attitude and Practice among Surgeons and Anesthesiologists

E. Hammami¹, M. Cheikhrouhou¹, M.Y. Kaabar¹, S. Guermazi¹
Abstract Number: LPB0107

Preoperative Measurement of Platelet Contribution to Clot Stiffness (PCS) with the Quantra® QPlus® System and Bleeding after Cardiac Surgery

T.B Washburn Jr¹, W. Houdijk², R. Sudhagoni²
Abstract Number: PB1086

Prescribing Patterns, Efficacy and Safety of Direct Oral Anticoagulants (DOAC) Usage in a Tertiary Hospital

K.Y. Yong¹, S. Leow², E.S. Yap¹, P.S. Ong², S.C. Tan¹, P.W. Goh¹
Abstract Number: OC 65.4

Prescription Patterns and Impact of Anticoagulant Therapy in Patients with Atrial Fibrillation who Had Active Cancer

C. Chai-Adisaksopha¹, A. Watanabe², P. Dilokthornsakul³, L. Navaravong², N. Chaiyakunapruk²
Abstract Number: PB0365

Presentation of the Patient with Low Peak Dabigatran Levels in Plasma Suggests the Importance of Quantitative Measurement of DOAC Drugs in Clinical Decision Making and Treatment

S. Margetić¹, I. Ćelap¹, A. Lovrenčić-Huzjan², M. Bosnar Puretić², M. Roje Bedeković², M. Razum¹, R. Mihić¹, S. Šupraha Goreta³
Abstract Number: PB0913

Prevailing c.2435delC and Other VWF Gene Defects in Russian Patients with von Willebrand Disease Type 3. Four New Pathogenic Variants Found

D. Chernetskaya¹, E. Likhacheva¹, F. Perina², O. Pshenichnikova¹, V. Surin¹, N. Zozulya¹
Abstract Number: PB1213

Prevalence and Incidence of Deep Vein Thrombosis in Medical Critically Ill Patients: A Prospective Analysis in a Single Tertiary Care Centre in Thailand

S. Arunothai¹, T. Panpikoon², K. Boonyawat³, Y. Sutherasan⁴, P. Theerawit⁴
Abstract Number: PB0929

Prevalence and Predictors of Iron Deficiency Anemia in Women with von Willebrand Disease: An NIS Study

A. Amouzegar¹, K. Jeong², J.G. Yabes², M.V. Ragni³
Abstract Number: PB0612

Prevalence of Hematuria in Patients with Hemophilia A and B and its Association with Comorbidities: Experience from a Brazilian Center

D. Bittencourt Siqueira¹, M. D'Auria Jacomassi¹, L. Bassolli¹, C. Rothschild¹, E. Okazaki¹, V. Rocha¹, P. Villaca¹
Abstract Number: PB0387

Prevalence of Hemolysis, Icterus and Lipemia in the Coagulation Laboratory: Database Analyses

F. Mil¹, B. Girard¹, A. Carlo², D. Guimbard¹
Abstract Number: PB0498

Prevalence of Hypertension in Hemophilia Patients: A Systematic Review

A. Ter-Zakarian¹, K. Al Banaa¹, R. Barnes¹, A. von Drygalski^1,2
Abstract Number: PB0831

Prevalence of Thrombotic Events and Risk Factors in Patients with Primary Immune Thrombocytopenia

A. Doblas-Marquez¹, F.-J. Lopez-Jaime¹, S. Martin-Tellez¹, I. Sanchez-Bazan¹, M.-I. Muñoz-Perez¹
Abstract Number: PB0811

Prevalence of Venous Thrombembolic Events in the Czech Pediatric Population – Epidemiological Study

T. Kuhn^1,2
Abstract Number: LPB0010

Prevalence of Venous Thromboembolism and Pulmonary Embolism among Patients Hospitalized with a COVID-19 Diagnosis in France

A. Gabet¹, C. Grave¹, P. Tuppin², J. Emmerich³, V. Olié¹
Abstract Number: PB0281

Prevalence, Clinical Profile and Bleeding Risk of Hospitalized COVID-19 Patients Receiving Anticoagulation: A Retrospective Cross-sectional Study

C. Imperial^1,1
Abstract Number: PB1093

Prevalence, Treatment and Prognosis of Tumor Thrombi in Renal Cell Carcinoma

F.H.J. Kaptein¹, S.J.E. Braken¹, E.M.E. du Chatinier¹, M.C. Burgmans², J.T. Buijs¹, S.C. Cannegieter^1,3, E.J. van Gennep⁴, R.C.M. Pelger⁴, E.L. van Persijn van Meerten², H.H. Versteeg¹, M.V. Huisman¹, T. van der Hulle⁵, F.A. Klok¹
Abstract Number: LB 01.1

Prevention Of Arterial And Venous Vascular Events In Symptomatic Peripheral Arterial Disease Patients After Lower Extremity Revascularization in the VOYAGER PAD trial: Dual Anticoagulant/Antiplatelet Regimen Vs Antiplatelet Therapy Alone

S.D. Berkowitz¹, R.M. Bauersachs², M. Szarek¹, M.R. Nehler¹, E.S. Debus³, M.R. Patel⁴, S.S. Anand⁵, C.N. Hess¹, E. Muehlhofer⁶, L.P. Haskell⁷, M.P. Bonaca¹
Abstract Number: OC 47.1

Prevention of Thrombocytopenia and Thrombosis in Heparin-induced Thrombocytopenia (HIT) Using Deglycosylated KKO: A Novel Therapeutic for HIT?

A. Sarkar¹, S. Khandelwal², S.V Yarovoi³, G.M Arepally², D.B Cines³, M. Poncz^1,4, L. Rauova^1,4
Abstract Number: PB0625

Primary Prophiliaxis was Associated with a Lower Risk of Joint Damage in Colombian Men Patients with Hemophilia A

G.A. Diaz Mosquera¹, S. Sarmiento Doncel², J.M. Cortes¹, F.J. Meza¹, J.E. Peña¹, C. Agudelo Rico³, N. Ramirez Plazas¹, C.A. Montaño Mejia¹, I.A. Perdomo Amar², A. Maza Villadiego¹, A. Parrado Rey¹
Abstract Number: LPB0045

Principles of Care for Women and Girls with Inherited Bleeding Disorders

K. van Galen¹, M. Lavin², N. Skouw-Rasmussen³, D. Noone³, D. Pollard⁴, K. Khair⁵, K. Gomez⁶, K. Fischer¹, E. van Loon⁷, C. Bagot⁸, P. Elfvinge⁹, R. D’Oiron¹⁰, R. Kadir¹¹
Abstract Number: PB0175

Prior Use of Therapeutic Anticoagulation Does Not Protect against COVID-19 Related Clinical Outcomes in Hospitalized Patients: A Propensity Score-matched Cohort Study

J. Spiegelenberg¹, M. van Gelder¹, M. Maas², M. Hovens³, A. Esselink⁴, A. Kerckhoffs⁵, J. Hoogerwerf¹, N. Janssen¹, M. van Apeldoorn⁵, K. Veerman⁶, M. Blaauw¹, R. Janssen⁴, R.J. Hassing³, T. Dofferhoff⁴, J. van de Maat¹, K. Kramers¹, J. Leentjens¹
Abstract Number: PB1084

Procedural Success of Left Atrial Appendage Occlusion Device in Patients with Chronic Kidney Disease: Meta-analysis of Real-world Data

A. Singh¹, S. Hussain², B. Antony¹
Abstract Number: PB0428

Producing if Tenecteplase with High Activity

D. Chashchinova¹, V. Leonov², X. Smolova², D. Kudlay¹
Abstract Number: PB0313

Profiling of Inflammatory Biomarkers and Coagulation Factors in End-stage Renal Disease

E. Bontekoe¹, A. Grewal¹, V. Bansal¹, M. Ben Hadj Tahar¹, D. Hoppensteadt¹, J. Fareed¹
Abstract Number: PB0236

Prognostic Coagulation Parameters in COVID-19 Patients at the ICU

S. van de Leur¹, S. Spanjersberg¹, E. ter Haar¹
Abstract Number: OC 73.3

Prognostic Impact of Acute Kidney Injury in Patients with Acute Pulmonary Embolism. Data from the RIETE Registry

L. Bertoletti^1,2,3,4, M. Murgier^5,6, B. Bikdeli^7,8,9, D. Jimenez¹⁰, J. Trujillo-Santos¹¹, A. Merah^1,12, C. de Ancos¹³, Á. Fidalgo¹⁴, J. Aibar¹⁵, M. Monreal¹⁶
Abstract Number: PB0012

Prognostic Significance of von Willebrand Factor in Flow-mediated Dilatation Test at Patients with Arterial Hypertension and Diabetes Type 2

E. Shorikov¹, D. Shorikova¹, P. Shorikov¹
Abstract Number: OC 44.3

Progression of Ischaemic and Haemorrhagic Brain Lesions on MRI in APS Patients on Antithrombotic Therapy

M. Efthymiou^1,2, P. SvrKova^3,4,2, R. Moll^1,2, S. Nallamilli^1,2, A.R. Alexandre^5,6, D. Isenberg^6,2, D. Werring^3,4,2, R.H Jager^3,4,2, H. Cohen^1,2
Abstract Number: PB0418

Prolonged Tourniquet Application in the Hind Limb of Rats Is Associated with Fibrinolysis

J. Chung^1,2, O. Mian^3,2, A.K. Chan^4,2, D. Matino^4,2
Abstract Number: PB0593

Promising Prospective Data on the Effect of Ankle Joint Distraction in Hemophilic Arthropathy: Three Year Follow-up

E. van Bergen^1,1, L. van Vulpen¹, H. Vogely¹, P. de Kleijn¹, W. Foppen¹, P. van Roermund¹, R. Schutgens¹, S. Mastbergen¹, F. Lafeber¹
Abstract Number: PB0490

Properties of FVIII Concentrate Were Obtained by the Method of Dye-ligand Affinity Chromatography

N. Shurko¹, T. Danysh¹, V. Novak¹
Abstract Number: PB0288

Prophylactic Anticoagulation in Hospitalized Patients with COVID-19: A Survey of Practices in Latin America

F. de Andrade Orsi¹, P. Casais², G. Cesarman-Maus³, C. Guillermo⁴, R. Martinez⁴, S. Rezende⁵
Abstract Number: PB1312

Prophylactic Radiological Interventions to Reduce Postpartum Haemorrhage in Patients with Placenta Accreta Spectrum Disorders

L. Bonsen^1,2, V. Harskamp³, S. Feddouli^1,3, J. Duvekot⁴, A. Pors³, K. Bloemenkamp⁵, J. van Roosmalen^1,6, M. van Kraaij⁷, J. Zwart⁸, J. van Lith¹, T. van den Akker^1,9, D. Henriquez^1,2,3, J. van der Bom^2,3, TeMpOH-3 study group
Abstract Number: PB0919

Prophylactic Subcutaneous Emicizumab-kxwh in Adults and Children with Symptomatic Type 3 von Willebrand Disease

A. Pawar¹, K. Braunstein², J. Michals¹, K. Vo¹, K. Schafer¹
Abstract Number: OC 51.1

Prospective Cohort Study on the Use of Low Molecular Weight Heparin Calibrated Anti-Xa Assay to Estimate Levels of Direct Oral Xa Inhibitors in Ex-vivo Patient Samples

M.S. Lim¹, R. Hayes², A. Sharma³, T. Kitipornchai², M. Mohamed¹, S. Mcrae¹
Abstract Number: PB1210

Prospective Cohort: A 10 Years Experience with Hospitalized Patients with Venous Thromboembolic Disease from a Single-center Institutional Registry, Argentina

F.J. Vázquez¹, M.F. Grande Ratti¹, M.A. Burgos¹, M.E. Zapiola¹, D.H. Giunta¹, M.L. Posadas-Martinez¹
Abstract Number: PB0599

Prospective, Non-interventional Study with a Cohort to Assess Real-world Effectiveness (RWE) and Safety of Emicizumab in Persons with Hemophilia A (PwHA) without Inhibitors in Spain, Hemolution Cohort

M.T. Álvarez Román¹, I. Soto², H. de la Corte¹, P. Bosh³, Á. Lavandeira⁴, C. Alvarez⁵, I. Guerra⁵
Abstract Number: PB0502

Prospective, Open-label, Multicentre Phase II Study (PeKaFIX) to Evaluate the Pharmacokinetic Parameters of a Plasma Derived Factor IX Concentrate and Build a Pharmacokinetic Bayesian Model

C. Negrier¹, on behalf of the PekaFIX study Group
Abstract Number: PB0615

Prostate Surgery in Patients with Hemophilia: A Monocentric Real-life Experience

N. Drillaud¹, B. Mesnard², M. Sigaud¹, M. Fouassier¹, C. Ternisien¹, M.-C. Bene³, J. Branchereau², M. Trossaërt¹
Abstract Number: OC 35.3

Protein Arginine Deiminase 4 Inactivates Tissue Factor Pathway Inhibitor by Post-translational Modification of Functional Arginine Residues

M.C.L. Thomassen¹, B.R. Bouwens¹, K. Wichapong¹, D.P. Suylen¹, F.G. Bouwman², T.M. Hackeng¹, R.R Koenen¹
Abstract Number: OC 35.2

Protein S Coordinates the Synergistic Inhibition of Prothrombinase by Tfpiα and Activated Protein C

X. Li¹, X. Song¹, M.M. Sim¹, J.P. Wood¹
Abstract Number: PB0395

Protein S Gla Domain as Theranostic for Early Vascular Calcification

A. Gentier¹, S. Agten¹, L. Schurgers¹, T. Hackeng¹
Abstract Number: PB0315

Proteome Analysis of Extracellular Vesicles from Patients with Myocardial Infarction and Relation to Heart Function: An Observational Study

A. Khandagale¹, S. Bergström Lind², G. Shevchenko², J. Westerbergh³, B. Lindahl^1,3, A. Siegbahn⁴, C. Christersson¹
Abstract Number: LPB0044

Prothrombotic Biomarkers during Controlled Ovarian Stimulation for Assisted Reproductive Techniques

J. Hugon-Rodin¹, A. Casini², J. Bénard², A. Poncet², P. Fontana², N. Vulliemoz³, I. Streuli²
Abstract Number: PB0988

Prototyping of Physiological Stenosis with 2-photon Lithography for Thrombosis Studies

Y.J. Lim^1,2, Y. Li², E.E. Gardiner¹, W.M. Lee^1,2
Abstract Number: PB0760

PSGL-1 is Important for Platelet-monocyte Aggregate Formation and Monocyte Maturation in Lentiviral Infection

C. Lyons^1,2, E. Shirk¹, S. Vijay¹, A. Feng¹, M.R. Richardson¹, Z. Gholizadeh¹, B. Carlson¹, S. Guerrero-Martin^1,2, K. Metcalf Pate^1,2
Abstract Number: OC 34.1

Pulmonary Embolism and Deep Vein Thrombosis – Incidence, Comorbidities and Temporary Provoking Factors – A Nationwide Registry Study of 298,172 Patients

K. Glise Sandblad¹, S. Jern², J. Sörbo³, A. Rosengren¹, P.-O. Hansson¹
Abstract Number: PB1178

Pulmonary Embolism Diagnosis: Let’s Practice what we Preach. A Quality Improvement Study to Increase Adherence to Evidence-based PE Diagnosis in the Emergency Department

F. Germini¹, F. Al-haimus¹, Y. Hu¹, S. Niaz¹, N. Clayton¹, S. Mondoux¹, Q. Ibrahim¹, L. Thabane¹, K. de Wit¹
Abstract Number: PB0265

Pulmonary Embolism in COVID-19-Patients: Diagnostic Accuracy of D-dimer

F. Laouan Brem¹, C. Miri¹, H. Rasras¹, A. Boudouh², Y. Amane³, M.-A. Bouazzaoui⁴, S. Nasri³, I. Skiker³, N. Abda⁴, H. Kouismi², Z. Bazid¹, N. Ismaili^1,4, N. El Ouafi^1,4
Abstract Number: PB1146

Pulmonary Embolism in the Onset of Hematogenous Thrombophilia

V. Voitsekhovsky¹, T. Zabolotskikh¹, I. Sayapina¹, O. Prikhodko¹, T. Luchnikova¹, E. Romantsova¹, N. Grigoriev¹
Abstract Number: PB0176

Pulmonary Thromboembolism (PTE) in Hospitalised Patients with COVID-19: A National Study of Patients Managed in Critical Care and Ward Environments

M. McGettrick¹, A. MacLellan¹, P. McCaughey¹, C. Bagot², M. Brewis¹, N.N Lang³, M. Johnson¹, A.C. Church¹
Abstract Number: OC 55.2

Purifying the Needle in the Haystack: A Novel Immunoproteomic Pipeline for the Characterization Anti-FVIII Antibodies in Hemophilia A Inhibitor Patients

R. Chen¹, B. Doshi^2,3, S. Lopez⁴, X. Pan⁴, A.S. Fahad⁴, M.F. Gutierrez Gonzalez⁴, B. Dekosky⁴, V. Arruda^3,2, V. Bhoj¹, B. Samelson-Jones^3,2