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ISTH 2021 Congress

July 17-21, 2021. Philadelphia, PA.

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  • Abstract Number: PB0336

    Laboratory Assessment of DOAC Assays for FXa Inhibitors in the Presence of Reversal Agent Andexanet Alfa on the ACL TOP/TOP 50 Coagulation Analyzers

    A. Khan1, K. Shishko1, G. Lu2, V. Nguyen1, A. Winkler1

  • Abstract Number: PB1099

    Laboratory Monitoring of Coagulation State in Children with Acute Lymphoblastic Leukemia

    E. Seregina1,2, L. Zharikova1, N. Trubina1, M. Korsantiya1, M. Gracheva1, A. Poletaev1, T. Vuimo1,2, F. Ataullakhanov1,2,3,4, U. Rumyantseva1, A. Karachunskiy1

  • Abstract Number: PB0485

    Laboratory Monitoring of Emicizumab in Treated Patients – How Does APTT Compare?

    A. McCormick1

  • Abstract Number: PB0394

    Laboratory Testing in Patients Treated with Direct Oral Anticoagulants: Our Experience

    G. Garcia-Donas1, M. García1, M. Bonete1, A. Rodríguez1

  • Abstract Number: PB1067

    Laboratory Testing Platform Discrepancy between Current Singleplex-assay and New Multiplex-assay for Detecting and Quantifying IgM-anti-Cardiolipin-antibodies and other Anti-Phospholipid (APL)-antibodies: The Potential for Mis-diagnosis of the APL-syndrome

    M. Escobar1, T.E. Howard2, N. Montanez1

  • Abstract Number: PB0478

    Laboratory Verification of a Chromogenic Factor IX Assay Kit

    J. Tange1, M. Sridharan1, N. Heikal1, D. Chen1, R. Pruthi1

  • Abstract Number: PB0672

    Late Prophylaxis in Severe Hemophilia A: Effect on Functional Abilities

    M. Sousa-Pimenta1,2, L. Soares Miranda1, J. Ferreira1, A. Barros1, M. Coutinho1, S. Morais1, E. Cruz1

  • Abstract Number: PB0583

    Left Atrial Appendage Occlusion for the Management of Atrial Fibrillation in Persons with Hemophilia: A Case Report and Systematic Review of the Literature

    M.Y. Lim1, M.Y. Abou-Ismail1

  • Abstract Number: PB0819

    Length of Thrombopoietin Receptor Agonist (TPO-RA) Treatment and Persistence in Immune Thrombocytopenia (ITP): Real World United States Claims Analyses

    M. Vredenburg1, S. Kolodny1, M. Wojdyla1, H. Boyer1, T. Darden1

  • Abstract Number: PB0026

    Leo Buerger’s Disease: About 13 Cases

    I. Chabchoub1, R. Ben Salah1, N. Regaieg1, F. Frikha1, Z. Bahloul1

  • Abstract Number: PB0440

    Life-threatening Bleeding in Acquired Factor V Inhibitor Can Be Controlled Combining Platelet Transfusion and Recombinant Activated Factor VII Administration

    V. Robles1, C.A. Dávalos1, L.M. Serrano1, J. Torres1, R. Fernández1, P. Chamorro1, M.P. Chávez1, C. Fernández1

  • Abstract Number: PB0895

    Light Transmission Aggregometry (LTA) on TA-8V (Stago®): What about Normal Values?

    A. Dericquebourg1, M. Daniel2, J.-C. Bordet1, F. Sobas1, C. Nougier1, C. Negrier1,2, S. Le Quellec1,2

  • Abstract Number: PO101

    Lipid-based Encapsulated Methotrexate Nanoparticles-mediated Low Level Focused Ultrasound Sonoporation Therapy Decrease Inflammation and Restenosis after ArF Excimer Laser Angioplasty of Fibrocalcific Atherosclerosis

    H. Mehrad1,2, A. Foletti3,2

  • Abstract Number: OC 03.4

    Lipid-binding Antiphospholipid Antibodies Trigger Autoimmune Signaling in Severe COVID-19

    A. Hollerbach1, N. Müller-Calleja1, D. Pedrosa2, M.F. Sprinzl3, P.R. Galle3, L. Teyton4, W. Ruf2,4, K.J. Lackner1

  • Abstract Number: PO122

    Liver Resection and Perioperative Coagulation Management in Patient with Cirrhosis and HCC – A Case Report

    M. Skoko1, I. Mihic Lasan1, K. Bilic1, A. Stefic1, A. Jularic1, J. Dodig1, T. Bosnjak2, S. Misir Situm2, G. Brozovic2, D.V. Vrdoljak2, M. Mihaljevic3, T. Vucemilo1, T. Marinkovic Strumberger1

  • Abstract Number: OC 67.4

    Liver Safety Case Report from the Phase 3 HOPE-B Gene Therapy Trial in Adults with Hemophilia B

    M. Schmidt1, G.R Foster2, M. Coppens3, H. Thomsen1, D. Cooper4, R. Dolmetsch4, E.K Sawyer4, L. Heijink5, S.W Pipe6

  • Abstract Number: OC 77.3

    LMWH Prevents Platelet and Extracellular Vesicle Mediated Thrombo-inflammation in Preeclampsia

    S. Kohli1, K. Singh1, A. Gupta1, M. Lia2, H. Stepan2, B. Isermann1

  • Abstract Number: PB1195

    Location and Burden of Extremity Vein Thrombosis in Patients with Solitary versus Multiple Subsegmental Pulmonary Emboli

    R. Meverden1, Y. Hirao-Try1, D. Vlazny1, A. Casanegra1, D. Houghton1, D. Hodge2, L. Peterson1, R. McBane1, W. Wysokinski1

  • Abstract Number: PO181

    Long Term Recurrence of Venous Thromboembolism: A Retrospective Case-control Study

    G. Turatti1, L. Spiezia1, M. Marobin1, A. Poretto1, E. Borella1, C. Simion1, P. Simioni1

  • Abstract Number: PB0744

    Long Term Trends of Coagulation Parameters in People Living with HIV-1 Treated with Combined Antiretroviral Therapy

    S. Bhoelan1, J. Borjas Howard1, V. Tichelaar1,2, W. Bierman3, K. Meijer1

  • Abstract Number: OC 07.3

    Long-term Joint Outcomes in Hemophilia through Ultrasound: 2-year Interim Results from the Prospective J-DaUPHIN Study

    A. Nagao1, H. Takedani2, S. Orita1, K. Fukutake1,3, T. Suzuki1

  • Abstract Number: PB0019

    Long-term Outcome of Percutaneous or Surgical revascularization with and without Prior Stroke in patients with Three-vessel Disease

    N. Xu1, L. Jiang1, C. Zhang1, J. Xu1, R. Liu1, Y. Zhang1, X. Zhao1, R. Gao1, L. Song1, J. Yuan1

  • Abstract Number: OC 08.2

    Long-term Outcomes in Adolescents with Moderate or Severe Hemophilia A: A PedNet Study

    D.E. Schmidt1, A. Michalopoulou2, K. Fischer3, J. Motwani4, N. Gretenkort Andersson5,6, H. Pergantou2, S. Ranta1, for the PedNet Study Group

  • Abstract Number: PB0535

    Long-term Prophylaxis with Simoctocog Alfa in Children

    A. Klukowska1, M. Jansen2, S. Knaub3, R.J. Liesner4

  • Abstract Number: PB1237

    Long-term Risk of Recurrent Venous Thromboembolism after a First Contraceptive-related Event: Data from REVERSE Cohort Study

    D. Aziz1,2, L. Skeith3,4, M. Rodger5,6, E. Sabri1, M. Righini7, M. Kovacs8, M. Carrier1,2, S. Kahn5,9, P. Wells1,2, D. Anderson10, I. Chagnon11, S. Solymoss5, M. Crowther12, R. White13, G. Le Gal1,2

  • Abstract Number: OC 32.4

    Long-term Safety and Efficacy of the Anti-TFPI Monoclonal Antibody Marstacimab in Patients with Severe Haemophilia A or B: Results from a Phase 2 Long-term Treatment Study

    J. Mahlangu1, J.L. Lamas2, J.C. Morales2, D.R. Malan3, J.G. Teeter4, R.J. Charnigo5, M. Privette5, E. Hwang5, S. Arkin6

  • Abstract Number: PB1014

    Long-term Severe Platelet Dysfunction as a Form of Presentation of Familial Platelet Disorder with Predisposition to Acute Myeloid Leukemia (FPD/AML), due to a RUNX1 Variant

    M. Sousa-Pimenta1,2, M. Pereira1,3, C. Lau4,3, A. Gonçalves5,3, M. E. Oliveira5,3, E. Cruz1, R. Santos5,3, M. Lima4,3, S. Morais1,3

  • Abstract Number: LPB0140

    Long-term Survival after Venous Thromboembolism: A Prospective Cohort Study

    H. Nilius1, T. Mertins1, R. Boss1, M. Knuchel1, E. Blozik2, J.A. Kremer Hovinga3, S. Eichinger4, M. Nagler1,3

  • Abstract Number: PB0514

    Longer-term Efficacy and Safety of Concizumab Prophylaxis in Hemophilia A and Hemophilia A/B with Inhibitors: Results from the Main and Extension Parts of Concizumab Phase 2 Trials

    J. Astermark1, P. Angchaisuksiri2, G. Benson3, G. Castaman4, P. Chowdary5, H. Eichler6, V. Jiménez-Yuste7, K. Kavakli8, T. Matsushita9, L. Hvitfeldt Poulsen10, J. Oldenburg11, S. Zupancic Salek12, A. Shapiro13, A.P. Wheeler14, G. Young15

  • Abstract Number: PB0263

    Longitudinal Measurement of Whole Blood Viscoelastic Properties throughout the Course of Extracorporeal Membrane Oxygenation in COVID-19 Patients with Severe Acute Respiratory Distress Syndrome

    M. Lejeune1,2, G. Hekimian1,2, P. Masi1, G. Lebreton1,2, J. Chommeloux1, C. Desnos1, M. Pineton De Chambrun1, I. Martin-Toutain1, A. Nieszkowska1, N. Bréchot1, M. Schmidt1,2, C.-E. Luyt1,2, P. Leprince1,2, A. Combes1,2, C. Frere1,2

  • Abstract Number: PB0542

    Looking Beyond Fixed-Dose Rurioctocog Alfa Pegol Prophylaxis: Post Hoc Analysis of PK-guided Regimens from the PROPEL Phase 3 Study

    C. Escuriola-Ettingshausen1, M. Escobar2, J. Windyga3, B. Zulfikar4, S.D. Tangada5, W. Engl6, I. Honauer7, H.-Y. Lee7, R. Klamroth8

  • Abstract Number: PB0844

    Loss of Diagnostic Utility of D-dimers in Secondary Thrombotic Thrombocytopenic Purpura (TTP) in Patients with Human Immunodeficiency Virus (HIV) Infection

    S. Louw1, A. Mayne1, E.S. Mayne1

  • Abstract Number: OC 29.2

    Loss of G6b-B Confines Megakaryocyte Differentiation Potential and Promotes Osteosclerosis in Mice

    I.C. Becker1,2,3, G. Manukjan2, Z. Nagy2,1, M. Haffner-Luntzer4, M. Englert2,1, T. Heib2,1, T. Voegtle2,1, G. Carina2,1, R. Bharti1, S. Dietrich1, K. Mott2, J. Heck2,1, N. Schlegel2, T. Heckel1, D. Stegner2,1, I. Pleines2,1, A. Ignatius4, H. Schulze2, B. Nieswandt2,1

  • Abstract Number: OC 10.4

    Loss of P2Y1 Receptor Desensitization Does Not Impact in vivo Hemostasis or Thrombosis Despite Increased Platelet Reactivity in vitro

    D.S. Paul1, T. Blatt2, S. Murcia2, R.H. Lee1, E.G. Clark1, R.A. Nicholas3, W. Bergmeier1

  • Abstract Number: OC 37.1

    Loss of the Rap-GAP, Rasa3 Leads to Severe Thrombocytopenia Primarily due to αIIbβ3 Integrin-dependent Platelet Clearance in the Spleen

    R. Lee1, D. Ghalloussi1, P. Kramer1, J. Kenny1, B. Nieswandt2, W. Bergmeier1

  • Abstract Number: LPB0081

    Low Adhesion and Interaction Forces of Myh9 Mutant Platelets Lead to Impaired Clot Retraction and Unstable Thrombus Formation

    J. Baumann1, L. Sachs2, Z. Nagy1, I. Schoen3, A. Greinacher2, O. Otto4,5, R. Palankar2, M. Bender1.

  • Abstract Number: PB1214

    Low Awareness of Venous Thromboembolism among the General Population: A Call for Increased Public Enlightenment Programs

    H. Okoye1, T. Nwagha1, E. Ezigbo2, O. Nnachi3, O. Obodo4, O. Nnachi3, N. Amu4, I. Anigbogu1

  • Abstract Number: LPB0124

    Low Hemoglobin as a Biomarker for Paediatric Sinus Thrombosis

    B. Moiz1, S. Altaf1, R. Devi Ukrani1, A. Arif1, I. Akbar1, M. Wahhaab Sadiq1

  • Abstract Number: PB0248

    Low Incidence of Thrombotic Events in Patients with Covid19: A Cohort Study

    C. Vazquez1, M. Vallone1, F. Chuliber1, V. Privitera1, A. Ferraris1, R. Cantarella1, M.F. Indo1, V. Peuchot1, F.J. Vazquez1

  • Abstract Number: PB0839

    Low Plasma ADAMTS13 Activity Contributes to Increased Mortality Rate in Hospitalized Patients with Suspected Heparin-induced Thrombocytopenia

    M. Chan1, X.L. Zheng2

  • Abstract Number: PB0911

    Low Temperature Induces von-Willebrand Factor Expression via Increased Early Growth Response 1 Transcriptional Activity in Splenic Sinusoidal Endothelial Cells

    K. Horioka1,2, H. Tanaka3, K. Okaba1, N. Ishii1, A. Motomura1, H. Inoue1, K. Alkass2, H. Druid2, D. Yajima1.

  • Abstract Number: PB0918

    Low VWF Level due to Heterozygous p.P1127S Mutation of VWF: Clinical Phenotype and Biochemical Effects

    M. Tardugno1, M. Sacco2, S. Lancellotti2, F. Bernardi3, M. Pinotti3, A. Branchini4, E. De Candia5, L. Di Gennaro2, M. Basso2, B. Giusti6, G. Castaman7, R. De Cristofaro1

  • Abstract Number: PB0638

    Low-dose Prophylaxis in Severe Hemophilia A: A Single-center Study

    M. Borhany1, M. Abid1, R. Ahmed2, A. Jamal2, S. Zafar1, R. Nadeem2

  • Abstract Number: PB0284

    Lupus Anticoagulant and Outcome of COVID-19 Patients

    O. Oyedeji1, R. Laforest1, S. Philip1, Z. Otrock1

  • Abstract Number: OC 18.2

    Lupus Anticoagulant Interference Study on Various ACT Assays

    S. Chen1, E. Paje1, P. Yu1, M. Vega2, R. Bottenus1

  • Abstract Number: PB0192

    Lupus Anticoagulant Positivity is Not Associated with Venous Thromboembolism or In-hospital Mortality In COVID-19

    N. Gendron1, M.-A. Dragon-Durey1, R. Chocron1, L. Darnige1, G. Jourdi2, A. Philippe1, J. Hadjadj2, J. Duchemin2, L. Khider1, N. Yatim2, L. Mauge1, P. Gaussem1, C.M. Samama2, B. Planquette1, O. Sanchez1, J.L. Diehl1, T. Mirault1, M. Fontenay2, B. Terrier2, D.M Smadja1

  • Abstract Number: PB0160

    Lymphocyte-Platelet Adhesion and Lymphocyte-platelet Clusters in Patients with Coronavirus Infection SARS-COV-2 (COVID-19)

    A. Emelyanov1, A. Emelyanova1, E. Zaytseva1, V. Kuchinskaya1, S. Igumnov1, J. Igumnova1, Y. Vitkovsky1

  • Abstract Number: PB0990

    Lyophilized Human Platelets Interact with Fresh Platelets to Promote Hemostasis Under Shear in vitro

    B. Ishler1, A. Lee1, S. Torramadé-Moix2, S. Samambar2, M. Diaz-Ricart2, G. Escolar2, K. Moskowitz1

  • Abstract Number: PB0882

    Lyophilized Human Platelets Support Thrombosis Unlike Normal Platelets in the Presence of GPIIb/IIIa Antagonists

    M. Dickerson1, K. Moskowitz1

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