ISTH 2022 Congress Archives - ISTH Congress Abstracts

Abstract Number: PB0019

Bambi-deficiency enhances adipose tissue browning, ameliorates dyslipidemia and confers protection against atherosclerosis

C. Lee¹, O. Merhi El Hassan El Abdallah¹, J. Monkman¹, K. Woollard¹, J. Crawley¹, I. Salles-Crawley²
Abstract Number: OC 01.1

Base and Prime editing of DNA as a new therapeutic option for Hemophilia A

E. Tonetto¹, S. Pignani², G. Roman², A. Follenzi², F. Bernardi³, D. Liu⁴, M. Pinotti¹, D. Balestra¹
Abstract Number: PB0257

Benefits of prolonged anticoagulant treatment in a series of cerebral venous thrombosis in pediatric patients

R. Berrueco¹, A. Faura², A. Ruiz-Llobet³, M. Mesegué⁴, M. Solsona³, E. González-Forster³
Abstract Number: PB0699

Bevacizumab for refractory hereditary hemorrhagic telangiectasia

C. Almeida¹, A. Sarmento¹, S. Carvalho², G. Ferreira²
Abstract Number: PB0542

Bio-equivalence of Potency adjusted approved heparin solutions compared to a newly developed heparin solution.

E. Krupa¹, D. Hoppensteadt², W. Jeske¹, A. Farooqui¹, A. Kouta¹, O. Iqbal¹, B. Kantarcioglu³, R. Krämer⁴, J. Fareed²
Abstract Number: VPB1284

Biomarker Profiling to Investigate the Molecular and Cellular Pathogenesis of Endothelium in Atrial Fibrillation

G. Dungan¹, A. Odeh¹, F. Siddiqui¹, D. Hoppensteadt², O. Iqbal¹, A. Darki², J. Fareed², m. syed¹
Abstract Number: PB0082

Biomarkers in COVID-19: Association with disease severity and outcomes

M. Peralta¹, V. Muczynski², P. Lane³, L. Pagala³, A. Riddell³, S. Bhagani⁴, B. Agarwal⁵, K. Gomez⁶, A. Drebes³, J. McVey⁷, T. Kotecha⁸, D. Martin⁸, A. Davenport⁸, A. Laurence⁹, A. Brachat¹⁰, T. Sood⁸, L. Lanning³, T. Gandhi³, P. Chowdary¹¹
Abstract Number: VPB0940

Biomarkers of coagulopathy in patients with different types of acute leukemia

Y. Hisada¹, S. Archibald¹, K. Bansal², S. Dwarampudi², A. Mullen², S. Bhatia², R. Bhatia², N. Mackman¹, R. Gangaraju²
Abstract Number: PB1291

Biomarkers of endothelial cell dysfunction in HIV-infected patients

E. Mayne¹, T. Abdool-Carim², M. Lederman³, N. Funderburg⁴, S. Louw⁵
Abstract Number: PB0306

Biomarkers of HIV-associated thrombotic thrombocytopaenic purpura (HIV-TTP)

S. Louw¹, M. Gededzha², A. Mayne³, E. Mayne⁴
Abstract Number: OC 05.4

Biphasic thrombus formation and resolution during a coronavirus infection in the liver

M. Salzmann¹, J. Kral-Pointner¹, P. Gibler¹, J. Wojta¹, R. Plasenzotti¹, P. Hohensinner²
Abstract Number: PB0728

Bladder cancer patients have increased NETosis and impaired DNaseI-mediated NET degradation that can be therapeutically restored in vitro

R. Herranz¹, J. Oto¹, M. Hueso², E. Plana³, F. Cana², A. Fernández-Pardo², S. Bonanad⁴, C. Vera-Donoso⁵, M. Martínez-Sarmiento⁵, P. Medina²
Abstract Number: PB0670

Bleed Outcomes in the Moderate and Mild Hemophilia A Population Without Prophylactic Treatment in CHESS II and CHESS PAEDs

K. Khair¹, F. Nissen², E. Ferri-Grazzi³, J. O’Hara⁴, R. Ofori-Asenso⁵, M. Aizenas², H. Zhang², K. Moreno², T. Burke⁴, B. Nolan⁶
Abstract Number: PB0181

Bleeding according to FVIII activity in 641 children with non-severe haemophilia – data from the PedNet study group

M. de Kovel¹, C. Königs², S. Ranta³, C. Escuriola Ettingshausen⁴, K. Fischer⁵
Abstract Number: PB0237

Bleeding assesment in children with Noonan syndrome

A. Barg¹, E. Avishai², S. levy¹, y. yeshayahu¹, T. Livnat², G. Kenet³
Abstract Number: PB1237

Bleeding diathesis in a girl with biallelic variants in RASGRP2 gene affecting platelet CalDAG-GEFI function

J. Frontroth¹, M. Hepner², K. Downes³, C. Cervio¹, S. Annetta⁴, R. Sueldo⁵, B. Bianco⁶, G. Sciuccati⁷
Abstract Number: PO0002

Bleeding disorder in a critically ill patient

R. Pombal¹, L. Vieira², S. Lopes², R. Neto², J. Ribeiro², H. Gomes², M. Figueiredo³
Abstract Number: OC 70.5

Bleeding in non-severe haemophilia A and B – data from the PedNet study group.

M. de Kovel¹, C. Königs², S. Ranta³, C. Escuriola Ettingshausen⁴, K. Fischer⁵
Abstract Number: OC 34.1

Bleeding in Patients with Genitourinary Cancer compared to Non-Genitourinary Cancer Treated with Apixaban, Rivaroxaban, or Enoxaparin for Acute Venous Thromboembolism

T. Lang¹, D. Vlazny¹, D. Houghton¹, A. Casanegra¹, R. Meverden¹, D. Froehling¹, D. Hodge², L. Peterson¹, R. McBane¹, W. Wysokinski¹
Abstract Number: VPB1191

Bleeding of unknown cause or Unclassified Bleeding Disorder : single center experience in west Algeria.

B. DRISS¹, M. Moueden²
Abstract Number: OC 71.3

Bleeding Outcomes for Patients on Anticoagulant and Antiplatelet Therapy

J. Schaefer¹, J. Errickson¹, X. Kong¹, M. Ali², S. Edupuganti¹, B. Haymart¹, S. Kaatz³, D. DeCamillo¹, E. Kline-Rogers⁴, V. Shah³, S. Sood¹, J. Froehlich⁴, G. Barnes¹
Abstract Number: PB0192

Bleeding Rates in Severe Non-inhibitor Haemophilia A Patients Across US, EU4&UK and Japan

A. Amirah¹, I. Palau², A. Rosli¹, N. Allie²
Abstract Number: PB0499

Bleeding risk assessment in end-stage kidney disease: validation of existing risk scores and evaluation of a machine learning-based approach

S. Nopp¹, C. Spielvogel¹, S. Schmaldienst², R. Klauser-Braun³, M. Lorenz⁴, B. Bauer⁵, I. Pabinger⁵, M. Säemann⁶, O. Königsbrügge⁷, C. Ay⁵
Abstract Number: PB0056

Bleeding risk of intramuscular injection of COVID-19 vaccines in adult patients with therapeutic anticoagulation

N. Gendron¹, L. Khider², C. Le Beller², B. Espinasse³, C. Auditeau², W. Amara², G. Perrin², D. Lebeaux², A. Gaiffe⁴, S. Combret⁵, B. Bertin⁶, T. Mirault², D. Smadja⁷, O. Sanchez⁸, C. Tromeur⁹, B. Planquette¹⁰, F. Couturaud¹¹
Abstract Number: PB0709

Bleeding Story of An Adolescent: Factor VII Deficiency And Repeat Iliopsoas Bleeding

S. KARAMAN¹, A. UNUVAR², ş. şahin³, C. Ercan⁴, g. polat⁴, M. BILICI¹, D. TUGCU¹, G. TANYILDIZ¹, Z. KARAKAS¹
Abstract Number: PB0331

Bleeding tendency in thrombocytopenic patients due to impaired defects in primary and secondary hemostasis

N. Buntsma¹, A. Gasecka², S. Talsma³, J. Rytel⁴, K. Mądry⁴, G. Basak⁴, E. van der Pol⁵, R. Nieuwland⁶
Abstract Number: PB0908

Bleeding versus thrombosis: Case series on dilemma of VTE management in cancer patients and role of radiotherapy

A. Bolarinwa, O. Popoola, M. Elebute
Abstract Number: PB1050

Blockade of K-ras signalling prevents coagulatory phenotype of alternatively activated macrophages.

P. Haider¹, J. Kral-Pointner², M. Salzmann², B. Podesser³, J. Wojta², P. Hohensinner³
Abstract Number: PB0210

Blood Biodistribution and Vector Shedding of Valoctocogene Roxaparvovec in People with Severe Hemophilia A: Results from the Phase 3 GENEr8-1 Trial

S. Agarwal¹, K. Obrochta¹, M. Vora¹, A. Bowen¹, B. Bunch¹, J. Holcomb¹, D. Guo¹, T. Robinson², K. Jayaram¹, C. Russell¹, C. Vettermann¹, J. Henshaw¹
Abstract Number: VPB0134

Blood coagulation parameters in hospitalized patients with COVID-19 – data from Regional Center for transfusion medicine Shtip

M. SHOROVA¹, r. Grubovik-Rastvorcev², E. Petkovic³, D. Stambolieva⁴, N. Jovanova⁵
Abstract Number: PB0351

Blood transfusion maintains endothelial cell quiescence – implications in the prevention of stroke in paediatric sickle cell anaemia

H. Fogarty¹, S. Ward², E. Karampini², S. Elliott³, A. Rehill², A. Ahmad², J. Velasquez², R. Geoghegan⁴, H. Conroy⁴, M. Byrne⁵, U. Budde⁶, E. Tuohy⁷, C. McMahon⁴, J. O'Donnell²
Abstract Number: VPB0114

BNT162b2 mRNA SARS-CoV-2 vaccination does not cause upregulation of endothelial activation markers or hypercoagulability: A Prospective, Single-Arm, Longitudinal Study.

X. Lim¹, B. Leung², C. SUM³, G. Lim⁴, C. CHUA¹, T. TU⁵, K. RAMANATHAN⁶, M. HUANG², H. HOWE¹, B. Fan⁷
Abstract Number: OC 29.1

Both α- and γ-chain crosslinks mediated by FXIIIa affect fibrin fibre resistance to rupture

T. Feller¹, C. Duval², S. Connell³, R. Ariëns⁴
Abstract Number: OC 03.3

Bradykinin Liberation from High Molecular Weight Kininogen by Plasma Kallikrein on Endothelial Cell Membranes is Modulated by Ambient Concentration of C1 inhibitor and Prolylcarboxypeptidase

A. Merkulova¹, S. Abdalian², G. Forbes³, P. Zeng³, A. Pinheiro³, A. Schmaier⁴
Abstract Number: OC 48.5

Brain cancers and the risk of intracranial hemorrhage with Direct Oral Anticoagulants (DOACs) versus Low Molecular Weight Heparin (LMWH): A meta-analysis of comparative studies

P. Haddad, D. Hammoud, K. Gallagher
Abstract Number: PB0199

Budget impact of increasing rVIII-SingleChain use in patients in Italy with moderate and severe hemophilia A

S. Yan¹, R. Tomic², M. Panebianco², E. Dlotko³, L. Stern³, R. Marino⁴
Abstract Number: PB1110

Buffy-coat-derived megakaryocytes for monoclonal antibody immobilization of platelet antigens (MAIMA) assay

G. Uzun¹, J. Lucic², K. Althaus³, F. Rigoni⁴, F. Lyshy¹, S. Nowak-Harnau¹, I. Marini⁴, U. Sachs⁵, T. Backchoul⁶
Abstract Number: PB0825

Burden of Illness in Patients With von Willebrand Disease Receiving Prophylaxis Versus Potential Prophylaxis-Eligible Patients: A Post-Hoc Analysis of A European Socioeconomic Study

P. Du¹, G. Morgan², S. Brighton², F. Truong Berthoz³, N. Kemenyash³, S. Sun¹
Abstract Number: PB0654

Burden of Treatment for Adult and Adolescent People with Haemophilia (PwH): Concept Elicitation Results Supporting the Development of the Hemophilia Treatment Experience Measure (Hemo-TEM)

M. Brod¹, L. Waldman², J. Skov Neergaard³, A. Busk³