ISTH 2022 Congress Archives - ISTH Congress Abstracts

Abstract Number: PB1289

Gasdermin D is dispensable for NET formation in vivo

H. Englert¹, C. Rangaswamy¹, M. Divivier¹, J. Göbel¹, I. Hermans-Borgmeyer¹, K. Mowen², T. Fuchs¹, T. Renné³
Abstract Number: VPB0161

Gene Expression after Hemarthrosis Differs Among Recombinant FVIII and FVIII-Fc Fusion Replacement in FVIII-Deficient Mice

B. Chumappumkal Joseph¹, T. Whisenant², E. J Cooke³, J. Zhou⁴, S. Ruiz⁵, D. Rattanamansuang⁵, A. von Drygalski⁴
Abstract Number: PB0176

Gene expression profile in severe Hemophilia A patients developing anti-Factor VIII neutralizing alloantibodies

A. Cairo¹, S. Spena¹, E. Pappalardo², M. Mortarino³, I. Garagiola⁴, F. Peyvandi⁵
Abstract Number: PB0578

Generation and characterization of novel nanobodies inhibiting factor XI function

A. Bar Barroeta¹, J. Marquart², K. Bakhtiari², R. Urbanus³, J. Meijers⁴
Abstract Number: PB1303

Generation of iPSC-derived vascular cells deficient in tissue factor pathway inhibitor

V. Bröker¹, A. Akbulut², L. Schurgers³, T. Hackeng³
Abstract Number: OC 74.2

Generation of zebrafish f9like mutant by CRISPR/Cas9 technology

S. Dhinoja, A. De Maria, P. Jagadeeswaran
Abstract Number: PB0714

Genetic and clinical characterization in 106 patients with congenital quantitative and qualitative fibrinogen deficiencies: a Slovak centre experience

T. Simurda¹, J. Zolkova², M. Sterankova³, Z. Kolkova⁴, D. Loderer⁴, M. Dobrotova², I. Plamenova², P. Holly², J. Hudecek², I. Skornova², M. Brunclikova², M. Grendar⁴, Z. Lasabova⁵, J. Stasko², P. Kubisz²
Abstract Number: OC 44.2

Genetic deletion of Prenylcysteine Oxidase 1 (PCYOX1) impairs arterial thrombosis in mice.

P. Amadio, C. Banfi, M. Zarà, M. Brioschi, S. Ghilardi, L. Sandrini, S. Barbieri
Abstract Number: VPB0140

Genetic triggers prothrombogenic status in Covid-19

N. Vorobyeva¹, A. Barteneva²
Abstract Number: PB0048

Genetic variants and biological markers of coagulation and inflammation to predict the survival outcome upon SARS-CoV-2 infection in a cohort of patients from the first wave of COVID-19 in Argentina

F. Aranda¹, S. Perés¹, E. Cunto², V. Chediack², M. Peralta², A. Bocassi², J. Valero², M. Svencionis³, J. Chamorro², T. Rubilar⁴, A. Crespi Abril⁴, G. de Larrañaga⁵
Abstract Number: PB1082

Genomic screening of patients with bleeding tendency of unknown cause

E. Leinoe¹, A. Ørslev Rasmussen², M. Rossing²
Abstract Number: PB0027

Glenzocimab does not impact bleeding severity in two different mouse models of intracranial hemorrhage

H. Lebas¹, S. Dupont², E. Pascal³, M. Jandrot-Perrus⁴, B. Ho-Tin-Noé⁵
Abstract Number: PB0173

Global coagulation assays in hemophilic patients on emicizumab prophylaxis, with and without partially neutralizing anti-drug antibodies

S. Arcudi¹, M. Clerici², E. Scalambrino³, R. Gualtierotti⁴, G. Nicolò⁵, G. Cafasso⁶, E. Biguzzi², C. Novembrino⁷, C. Valsecchi², A. Tripodi², F. Peyvandi⁸
Abstract Number: OC 59.5

Glucocorticoids Stimulate Thrombopoiesis in Murine Megakaryocytes

M. Grodzielski, J. Cidlowski
Abstract Number: OC 03.4

Glycated albumin modulates the contact system with implications for the kallikrein-kinin and intrinsic coagulation systems

L. Hardy¹, D. Bohinc², K. Bane³, S. Heal⁴, E. Hethershaw⁵, M. Ali⁴, R. Foster⁴, C. Longstaff⁶, T. Renne⁷, E. Stavrou⁸, H. Philippou⁴
Abstract Number: PB1209

Glycoprotein-specific Platelet Autoantibodies Predict Lower Platelet Counts in Thrombocytopenic Patients

U. Sachs¹, M. Reich², D. Qiu³, N. Cooper⁴, G. Bein⁴
Abstract Number: OC 75.2

GP1b-FilaminA interaction regulates megakaryocyte localization and budding during platelet biogenesis

M. Ellis¹, A. Terreaux², R. Smythe³, A. Eckly⁴, S. Cranmer⁵, J. Maclean³, I. Alwis³, J. Perdomo⁶, F. Passam¹, S. Taoudi², F. Lanza⁷, Y. Yuan⁸, J. Shaun¹
Abstract Number: PB0385

GPIbα shedding is restricted to the inner platelet membrane

K. Six¹, M. Van den Hauwe², R. De Rycke³, I. Sagi⁴, E. Gardiner⁵, V. Compernolle⁶, H. Feys⁷
Abstract Number: PB0387

GPR56 is the platelet collagen receptor activator of G protein 13

L. Pan¹, T. Bernadyn², R. Adili³, M. Holinstat⁴, G. Tall²
Abstract Number: PB1286

GPVI drives pulmonary inflammation by mediating platelet-neutrophil complex formation in a murine model of ARDS

P. Burkard¹, C. Schonhart², D. Köhler³, P. Rosenberger³, B. Nieswandt²
Abstract Number: PB0384

GPVI is a binding site for factor VIII on platelets

R. Sekar¹, A. Mimoun², M. Bou Jaoudeh³, S. Loyau⁴, S. Delignat⁵, V. Daventure⁵, J. Rayes⁶, Y. Boulaftali⁷, M. Jandrot-Perrus⁸, V. Proulle⁹, S. Lacroix-Desmazes¹⁰
Abstract Number: VPB0409

GRK2 regulates ADP signaling in platelets

X. Zhao¹, M. Cooper¹, Y. Yarman¹, J. Michael¹, K. Chuprun², W. Koch², S. McKenzie¹, M. Tomaiuolo¹, T. Stalker¹, L. Zhu³, P. Ma¹
Abstract Number: OC 17.1

Growth differentiation factor-15 is related to adverse prognosis in patients with polyvascular disease receiving dual antithrombotic therapy

E. Krivosheeva¹, A. Komarov², A. Dobrovolsky², E. Titaeva², O. Pogorelova³, T. Balakhonova³, E. Panchenko²
Abstract Number: OC 32.4

Gut microbiome composition and intestinal immunity in antiphospholipid syndrome patients versus healthy controls

V. Jansen¹, M. Davids¹, D. van Mourik¹, J. Levels¹, S. Middeldorp², M. Nieuwdorp¹, T. van Mens¹