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ISTH 2022 Congress

July 9-13, 2022. London, England, UK.

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  • Abstract Number: VPB0943

    Laboratory assessment of prothrombotic status in patients with primary brain tumors

    O. Melniсhnikova1, J. Zhilenkova2, E. Zolotova2, O. Sirotkina3, K. Pishchulov4, T. Vavilova4, O. Moiseeva4, M. Simakova4

  • Abstract Number: PB0412

    Laboratory detection of Lupus Anticoagulant using Dilute Russell’s Viper Venom test (DRVVT) and/or Activated Partial Thromboplastin time (APTT): Does it matter?

    T. Geevar1, R. Dave1, P. Elizabeth2, A. Samuel3, J. Thamburaj3, J. Mammen3, S. Nair1

  • Abstract Number: PB0180

    Laboratory evaluation of extendend-half-life recombinant FVIII products (EHL-FVIIIs): one stage coagulation assay or chromogenic assay?

    R. De Cristofaro1, S. Lancellotti2, M. Sacco1, M. Tardugno1

  • Abstract Number: VPB0227

    Laboratory monitoring in haemophilia A patients with factor VIII inhibitor treated with emicizumab

    C. Novembrino1, M. Boscolo-Anzoletti2, E. Galbiati2, F. Peyvandi3

  • Abstract Number: PB1085

    Laboratory versus point-of-care INR testing in patients with lupus anticoagulant – a retrospective cohort analysis

    A. Lubetsky1, O. Cohen2, M. Misgav2, S. Lalezari2, G. Kenet3

  • Abstract Number: PB0812

    Lack of Congruent VWF Levels, Genetics, and Bleeding Symptoms in Families with a Type 1 von Willebrand Disease Diagnosis

    M. Schilthuis1, P. Christopherson2, S. Haberichter3, A. Paterson4, R. Montgomery3, V. Flood1

  • Abstract Number: PB0015

    Left atrium size is associated with fibrin clot ultrastructure in patients with acute myocardial infarction

    A. Siniarski1, S. Baker2, K. Stępień3, R. Ariëns4, A. Gackowski3, G. Gajos5, J. Nessler5

  • Abstract Number: OC 51.3

    Leptin and IL-6 are linked to the mechanism underlying the prothrombotic state in obese pregnant women

    S. McNeill1, F. Jordan2, V. Gibson3, D. Freeman2, C. Bagot4

  • Abstract Number: PO0015

    Level of coagulation aberrations among COVID-19 patients in Ethiopia, Findings from the Horn of Africa

    Y. Tsegay1, M. Bitew2

  • Abstract Number: VPB0468

    Levels Of Heparin Induced Anti-PF4 Antibodies and Endogenous Glycosaminoglycans and Their Relationship with Inflammatory Biomarkers in Pulmonary Embolism Patients.

    B. Kantarcioglu1, A. Darki2, F. Siddiqui2, D. Hoppensteadt2, J. Lewis3, R. Krämer4, J. Fareed2

  • Abstract Number: PB0559

    LEX-210: a phase 3, randomized, double-blinded study of four-factor prothrombin complex concentrate in patients with acute major bleeding on direct oral anticoagulant therapy with factor Xa inhibitors

    R. Sarode1, S. Maack2, C. Solomon3, S. Knaub2

  • Abstract Number: VPB0492

    LEX-211 (FARES-II): a phase 3, prospective, active-control randomised study of four-factor prothrombin complex concentrate versus frozen plasma in bleeding adult cardiac surgery patients

    K. Karkouti1, J. Callum2, C. Solomon3, S. Knaub4

  • Abstract Number: PO0047

    Life threatening thromboembolic event associated to pregnancy in an adolescent woman

    T. Kuhn1, J. Pavlíček2

  • Abstract Number: OC 35.1

    Light-induced Ca2+ signaling triggers megakaryocyte polarization

    Y. Zhang1, S. Gao2, J. Yu-Strzelczyk2, H. Kurz3, G. Nagel4, M. Bender5

  • Abstract Number: PB1302

    Lineage specific vascular smooth muscle cell differentiation from pluripotent stem cells: A developmental bias towards aortic calcification

    A. Akbulut1, N. Rapp2, H. Davaapil3, S. Sinha3, L. Schurgers4

  • Abstract Number: OC 63.4

    Little discrepancy of one-stage and chromogenic assays in a large international cohort of patients with non-severe hemophilia A and B (DYNAMO study)

    A. Zwagemaker1, F. Kloosterman1, S. Gouw2, S. Boyce3, P. Brons4, M. Cnossen5, P. Collins6, J. Eikenboom7, C. Hay8, S. Jackson9, M. Kruip10, B. Laros-van Gorkom11, C. Male12, L. Nieuwenhuizen13, S. Shapiro14, K. Fijnvandraat15, M. Coppens16

  • Abstract Number: OC 37.5

    Liver sinusoidal endothelial cells as a novel target for tolerance induction to FVIII

    M. Leoni1, M. Miranda2, K. Fijnvandraat3, S. Lacroix-Desmazes4, J. Voorberg2

  • Abstract Number: OC 12.5

    Liver Sinusoidal Endothelial Cells Targeted with Ultrasound Mediated Gene Delivery Shows Long Term FVIII Expression in Hemophilia A Mice

    S. Lawton1, M. Manson2, M. Fan3, T. Chao3, P. Kim3, C. Campbell3, C. Chen3, X. Cai4, A. Vander Kooi3, C. Miao3

  • Abstract Number: VPB0514

    LMWH safety and efficacy in pregnancy with rheumatic heart disease patients with heart valves replacement

    F. Alqahtani1, N. Alghamdi2, L. allehyani2, H. Alosaimi2, W. Almutairi2

  • Abstract Number: PB0679

    Local experience of monitoring and effectiveness of Emicizumab in severe Haemophilia A

    J. Needham, S. Mangles, L. Oyesiku, H. Ma Cordial

  • Abstract Number: VPB0110

    Long-COVID-19 syndrome: from the clinical evidences to a pathophysiological mechanism

    P. Canzano1, M. Brambilla1, A. Becchetti2, M. Conti2, P. Agostoni2, S. Rovai2, M. Pengo3, E. Tortorici3, M. Mancini2, D. Andreini2, A. Bonomi2, F. Veglia2, G. Parati3, M. Camera4

  • Abstract Number: OC 14.2

    Long-term outcomes of superficial vein thrombosis in daily practice: 12-month data from the INSIGHTS-SVT study

    E. Rabe1, U. Hoffmann2, A. Schimke3, A. Heinken4, F. Langer5, T. Noppeney6, D. Pittrow7, J. Klotsche8, H. Gerlach9, R. Bauersachs10

  • Abstract Number: PB0098

    Long-term persistence of anti-PF4-antibodies following Vaccine-Induced Thrombotic Thrombocytopenia after first ChAdOx1 vaccination.

    M. Engelen1, F. Mullier2, M. Jacquemin3, M. Debasse4, K. Peerlinck5, K. Devreese6, C. Vandenbriele7, P. Verhamme8, T. Vanassche9

  • Abstract Number: OC 43.2

    Long-term reduction in blood transfusion incidence after correction of the shear-induced von Willebrand factor defect by TAVR-procedure

    A. Rauch1, F. Vincent2, T. Denimal2, H. Spillemaeker2, T. Pamart2, E. Jeanpierre3, M. Desvages1, M. Daniel1, A. Dupont1, E. Van Belle2, S. Susen4

  • Abstract Number: VPB0470

    Long-term results of tinzaparin for the treatment of superficial vein thrombosis of the lower limbs.

    C. Papageorgopoulou, K. Nikolakopoulos, S. Papadoulas, S. Kakkos

  • Abstract Number: OC 34.4

    Long-Term Risk of Clinically Relevant Non-Major Bleeding During Extended Anticoagulation for Unprovoked Venous Thromboembolism: A Systematic Review and Meta-Analysis

    F. Khan1, T. Tritschler2, P. Wells3, G. Le Gal3, M. Rodger4, D. Fergusson5

  • Abstract Number: PB0310

    Longitudinal kinetics of B-cell subsets in Immune Thrombotic Thrombocytopenic Purpura Patients: Relapses vs Remission

    M. Subhan1, J. Shin2, B. Craven1, R. de Groot1, Y. Guo3, G. Cambridge1, M. Scully2, M. Thomas4

  • Abstract Number: PB0159

    Loss of function variant in SMIM1 is associated with reduced energy expenditure, weight gain and an increased risk for cardiovascular events.

    L. Stefanucci1, C. Moslemi2, A. Tome3, D. Vuckovic4, M. Frontini5

  • Abstract Number: PB1398

    Loss of opportunities in the diagnosis and treatment of Primary obstetric antiphospholipid syndrome (POAPS). What is hidden behind the daily clinical practice?

    G. de Larrañaga1, S. Udry2, S. Perés3, F. Aranda3, S. Morales Perez4, C. Belizna5, E. Esteve-Valverde6, D. Fernández Romero7, J. Alijotas-Reig8, O. Latino7

  • Abstract Number: OC 53.5

    Loss of Rab27A Targeting to Weibel-Palade Bodies in Endothelial Colony Forming Cells of Patients with Biallelic Mutations in the Guanine Nucleotide Exchange Factor MAP-Kinase Activating Death Domain

    P. Burgisser1, M. Kat2, M. Swinkels3, S. Hordijk4, G. Korenke5, T. Hónzik6, R. Bierings7

  • Abstract Number: PO0010

    Loss of response after discontinuation of eltrombopag in a patient with immune thrombocytopenia secondary to COVID-19: another finding of “persistent COVID syndrome”?

    B. Diaz Jordan, V. Yepez Espinales

  • Abstract Number: PB0405

    Loss of zinc transporters ZIP1 and ZIP3 augments platelet reactivity in response to G protein-coupled receptor agonists and accelerates thrombus formation in vivo

    A. Elgheznawy1, P. Öftering2, M. Englert3, F. Kaiser4, C. Kusch3, U. Gbureck5, M. Bösl6, B. Nieswandt7, T. Vögtle8, H. Hermanns1

  • Abstract Number: PB0304

    Low ADAMTS13 activity rapid assay results in patients with low clinical probability of Thrombotic Thrombocytopaenic Purpura (TTP) – the United Kingdom experience

    S. MacDonald1, P. Murphy2, R. Fretwell3, C. Downey4, P. Baker5, E. Foxton6, C. Lawrence7, A. Ali8, V. Jenkins9, E. Vilar10, M. Besser1, E. Symington1, M. Robinson1, M. Desborough5, W. Thomas1, J. Yong4, T. Dutt4

  • Abstract Number: PB0539

    Low antithrombin levels are associated with low risk of cardiovascular death but are a risk factor for cancer mortality

    L. Iacoviello1, R. de Laat-Kremers2, S. Constanzo1, Q. Yan3, A. Di Castelnuovo4, L. Van der Vorm5, A. De Curtis1, M. Ninivaggi6, C. Cerletti1, M. Donati1, B. de Laat5

  • Abstract Number: PB0926

    Low concentrations of rFVIIa bypass changes in ROTEM coagulation parameters induced by abelacimab in vitro

    Y. Khder1, S. Cote2, P. Hoffmann3, D. Bloomfield4

  • Abstract Number: PB0779

    Low expression of coagulation inhibitors in the immune microenvironment in precursor stages of multiple myeloma

    X. Cui1, K. Yang2, J. Myklebust3, L. Munthe3, F. Schjesvold4, G. Tjønnfjord4, B. Stavik2, P. Sandset5

  • Abstract Number: VPB0136

    Low incidence of thromboembolism in hospitalized COVID-19 patients despite a very low thromboprophylaxis rate in Thailand

    N. Tangcheewinsirikul1, N. Uaprasert2, P. Rojnuckarin3

  • Abstract Number: PB0677

    Low level mosaicism in a boy with mild haemophilia A excludes his mother as a carrier.

    M. Mitchell1, R. Wheeler2, J. Cutler2, S. Mangles3

  • Abstract Number: PB0455

    Low molecular weight heparin beyond 12 months in patients with cancer associated thrombosis. CAT-LONG study.

    S. Lopez-Ruz1, M. Barca-Hernando1, S. Marin-Romero2, M. Elias-Hernandez3, R. Otero-Candelera3, L. Jara-Palomares3

  • Abstract Number: PB0620

    Low molecular weight heparin slows the formation of clots from patients within twenty-four hours of acute PE

    S. Baker1, G. Halliday2, R. Ariëns3

  • Abstract Number: PB0189

    Low normal levels of factor V enhance thrombin generation in hemophilia A

    D. Monroe1, C. Baird2, J. Peterson3, A. Fogelson4, K. Leiderman5, S. Sindi6, M. Stobb7, A. Mast3, M. Manco-Johnson8, K. Neeves2

  • Abstract Number: PB0850

    Lowe syndrome in platelets: OCRL controls the reorganization of actin and tubulin filaments during platelet activation

    A. Bura1, M. Bender2, A. Jurak Begonja1

  • Abstract Number: VPB0516

    Lp(a) increase calcium phosphate aortic valve mineralization in patients with a previous myocardial infarction.

    A. de la Peña1, M. Flores-Garcia2, G. Cardoso-Saldaña3, V. Herrera3, C. Linares-Lopez4, J. Villegas-Hernandez5, R. Ledezma6, M. Peña-Duque5, M. Martinez- Rios5, E. Angles-Cano7

  • Abstract Number: PB0041

    Lung Ultrasound (LUS) for Thrombosis in COVID-19 Patients

    K. Bielosludtseva, K. Fuhol, M. Krykhtina

  • Abstract Number: PB0078

    Lupus anticoagulant as predictor for thrombosis in critically ill COVID-19 patients: a retrospective cohort study

    T. Noordermeer1, R. Schutgens2, C. Visser3, E. Rademaker4, M. de Maat5, A. Jansen6, M. Limper7, O. Cremer8, M. Kruip9, H. Endeman10, C. Maas11, B. de Laat12, R. Urbanus1

  • Abstract Number: PB0064

    Lupus anticoagulants as an independent predictor for disease severity in COVID-19 patients

    H. Kim1, D. Chu2, S. Jang2

  • Abstract Number: PB0154

    Lyophilized human platelets are superior to apheresis or fresh-drawn platelets in their ability to accelerate thrombin production

    L. Booth1, M. Dickerson2, K. Moskowitz1

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