ISTH 2022 Congress Archives - ISTH Congress Abstracts

Abstract Number: PB0343

N-Acetyl Cysteine Prevents Occlusive Arterial Thrombosis in a Dose-Dependent Manner

C. Bresette¹, K. Ashworth², J. Di Paola³, D. Ku⁴
Abstract Number: OC 04.3

N-glycan-mediated shielding of ADAMTS13 effectively prevents binding of pathogenic autoantibodies in high-titer patients with immune-mediated Thrombotic Thrombocytopenic Purpura

T. Postmus¹, N. Graca², B. Ercig², B. Luken³, P. Coppo⁴, A. Veyradier⁵, K. Vanhoorelbeke⁶, J. Voorberg⁷
Abstract Number: OC 77.2

Na+/K+ ATPase alpha 1 subunit participates in platelet signaling and is a potential anti-thrombotic target

O. Li¹, R. Aguilar², R. Roytenberg¹, H. Yue³, E. Thompson², S. Pierre⁴, J. Liu¹, W. Li³
Abstract Number: OC 61.5

National Incidence of Bleeding-Related Hospitalisations and Mortality by Anatomical and ISTH site classification in England 2014-2019

K. Creeper¹, A. Stafford², S. Choudhuri³, N. Tumian⁴, K. Breen⁵, A. Cohen⁶
Abstract Number: PB0981

Nationwide analysis of Pre-Hospital Tranexamic Acid in trauma patients at risk of bleeding

A. Almuwallad¹, A. Rossetto², E. Cole², R. Davenport³
Abstract Number: PB0053

NET formation in patients with COVID-19 and non-COVID-19 ARDS on venovenous ECMO

N. Buchtele¹, M. Kollars², H. Burgmann³, P. Kyrle², T. Staudinger⁴, S. Eichinger⁵, L. Traby⁶
Abstract Number: PB0745

NETosis in Sickle Cell Anemia

A. TOMBAK¹, G. Hatem², L. Tamer², N. Tiftik², N. Yilmaz²
Abstract Number: PB1400

Neurologically asymptomatic patients with pure obstetric antiphospholipid syndrome cumulate progressive microstructural brain damages, mild functional abnormalities, and subtle cognitive impairments

J. GRIS¹, S. Sandiramourty², T. Hai Nguyen², J. Beregi², F. Pereira³
Abstract Number: PB0008

Neutralizing anti-emicizumab antibodies in a patient with Acquired Hemophilia A

B. Pezeshkpoor¹, N. Sereda¹, A. Berkemeier¹, J. Müller², S. Singh¹, S. Ramaraje Urs², C. Klein¹, S. Horneff¹, G. Goldmann¹, N. Marquardt¹, J. Oldenburg³
Abstract Number: PB0221

Neutralizing antidrug antibody to emicizumab: Detailed laboratory evaluation and review of the literature

H. KIZILOCAK¹, J. Brown², G. Young³
Abstract Number: PB0731

Neutrophil activation markers as novel biomarkers for advanced stages of high-grade serous ovarian cancer

J. Oto¹, B. Mc Cormack², S. Tomás-Pérez², A. Fernández-Pardo³, E. González-Cantó², F. Cana³, C. Aghababyan⁴, R. Herranz¹, S. Cañete-Mota⁵, A. Cuadros-Lozano⁴, L. Martínez-Fernández⁴, A. Aranda-Borreda², A. Arroyo-Álvarez², N. Santonja-López⁶, R. Ramírez-Belloch⁷, A. Llueca-Abella⁸, J. Marí-Alexandre J², J. Gilabert-Estellés⁹, P. Medina³
Abstract Number: OC 46.2

Neutrophil Cathepsin G Cleaves Fibrinogen Affecting Clot Structure

S. Smith, J. Morrissey
Abstract Number: OC 68.5

Neutrophil Extracellular Traps as a Mediator of Cerebral Ischemia and Reperfusion Injury in Ischemic Stroke

M. De Wilde¹, S. Staessens¹, L. Desender¹, C. Tersteeg², K. Vanhoorelbeke², S. De Meyer²
Abstract Number: OC 20.1

Neutrophil Extracellular Traps promote joint injury in hemophilia

T. Kaminski, T. Brzoska, E. Tutuncouglu, M. Ragni, P. Sundd
Abstract Number: OC 38.2

Neutrophils and platelets collaborate to induce an increase NET formation during JAK2V617F positive myeloproliferative neoplasms

A. Guy¹, V. Gourdou-Latyszenok², L. Wolff-Thrombini², S. Favre², S. Labrouche-Colomer³, M. Renault², C. James²
Abstract Number: OC 72.2

Neutrophils protect against Staphylococcus aureus endocarditis but the impact of NET release is negated by coagulases

S. Meyers¹, M. Lox², S. Kraisin², C. Martens³, L. Liesenborghs², L. Frederix², D. Missiakas⁴, P. Baatsen⁵, T. Vanassche⁶, P. Verhamme², K. Martinod³
Abstract Number: PB0371

New experimental evidence for a role of platelets in cholesterol-induced vascular and valvular calcification

Z. Jiang¹, C. Oury²
Abstract Number: VPB1168

New Technologies such as Virtual Reality to increase Adherence in Hemophilia Treatment

A. santamaria¹, T. Lobez², M. Sanchez³, S. García Barcenilla⁴, J. Farriol⁵, L. Pérez⁶, D. García⁶
Abstract Number: PB1059

Next-generation FVIII mimetic, Mim8, does not interfere with non-factor VIII haemostasis assays.

A. Bowyer¹, K. Hickey², S. Kitchen³, M. Ezban⁴
Abstract Number: VPB0109

NLRP3 inflammasome activation and immunothrombosis in COVID-19.

A. Cambon¹, C. Guervilly², C. Delteil³, R. Bachelier⁴, N. Potere⁵, E. Abdili⁶, J. Forel⁷, F. Dignat-George⁸, S. Hraiech², R. Lacroix⁹, L. Papazian¹⁰, G. Kaplanski¹¹
Abstract Number: VPB0696

No difference in the management of Covid-19 hemophilic and non-hemophilic patients

G. Sottilotta¹, G. Nicolò², C. Mangano³, F. Luise⁴, A. Piromalli⁴
Abstract Number: PB0441

No pharmacological effect of the P-glycoprotein inhibitor tamoxifen on edoxaban plasma levels in patients with breast cancer: the PHIX-IT study

F. Bosch¹, F. Mulder², A. Willemsen³, M. Rentinck³, N. van Es⁴, R. Mathôt⁵, P. Kamphuisen⁶
Abstract Number: OC 45.3

Non-invasive In Vivo Thrombus Imaging in Patients with Ischaemic Stroke or Transient Ischaemic Attack.

B. Whittington¹, D. Newby¹, E. Tzolos¹, M. Williams¹, J. Wardlaw², E. Van Beek³, R. Bing¹, T. Clark¹, C. Lucatelli¹, W. Whiteley¹, P. Slomka⁴, M. Dweck¹, A. Stephens⁵, N. Koglin⁵
Abstract Number: VPB1350

Non-O Blood Type is Risk Factor for Venous Thromboembolism in Acutely Injured Patients Requiring Orthopaedic Surgery

P. Schneider, S. Yee, J. Petrowitsch, A. Clarke, L. Yamaura, K. Rondeau, L. Skeith
Abstract Number: PB1281

Non-parenchymal origin of alternatively spliced tissue factor in chronic liver disease

C. Lewis¹, K. Stone¹, D. Kuhnell², S. Langevin², A. Soto-Gutierrez³, P. Van Dreden⁴, J. Luyendyk⁵, V. Bogdanov⁶
Abstract Number: PB1175

Norwegian Real-World Experience with recombinant factor IX Fc (rFIXFc) in Haemophilia B (HB) Patients

P. Holme¹, H. Glosli², J. Thanner³, K. Sennfält³
Abstract Number: PB1176

Norwegian Real-World Experience with recombinant factor VIII Fc (rFVIIIFc) in Haemophilia A (HA) Patients

P. Holme¹, H. Glosli², J. Thanner³, K. Sennfält³
Abstract Number: PB1127

Novel accreditation of European haemophilia treatment and gene therapy centres

A. Boban¹, F. Baghaei Borzabadi², K. Fijnvandraat³, R. Klamroth⁴, W. Miesbach⁵, D. Stephensen⁶, M. Kavanagh⁷, D. Noone⁸, M. Crato⁹, F. Peyvandi¹⁰
Abstract Number: OC 26.3

Novel Flow Cytometric Diagnostic Assay for Primary Immune Thrombocytopenia.

P. Woolley¹, A. Constantinescu-Bercu², M. Stubbs³, R. de Groot², J. Westwood³, Y. Guo⁴, M. Scully⁵
Abstract Number: OC 64.3

Novel GNE gene variants associated with severe congenital thrombocytopenia and platelet sialylation defect – follow up data after hematopoietic stem cell transplantation

B. Zieger¹, D. Boeckelmann², W. Anani³, H. Falet⁴, J. Zhu³, H. Glonnegger¹, H. Full⁵, F. Andresen¹, M. Erlacher¹, E. Lausch⁶, S. Fels¹, B. Strahm¹, P. Lang⁷, K. Hoffmeister⁸
Abstract Number: PB1185

Novel miniaturized Chemiluminescent-based Factor VIII activity assay

D. Steeghs, M. van Geffen, W. van Heerde, C. van 't Veer
Abstract Number: PB1234

Novel Pathological GATA1 Variant Leads to Defective Platelet Biogenesis via Impaired Transcriptional Regulation

K. Butov¹, Z. Kondrashova², S. Obydennyi¹, A. Ignatova³, N. Podoplelova¹, M. Kurnikova¹, E. Raykina³, E. Osipova¹, G. Novichkova¹, E. Donyush², K. Machlus⁴, M. Panteleev⁵
Abstract Number: OC 59.4

Novel variants in GALE caused syndromic macrothrombocytopenia disrupting thrombopoiesis and glycosylation

A. Marin-Quilez¹, C. Di Buduo², L. Díaz-Ajenjo¹, P. Soprano³, E. Vuelta¹, I. Serramito-Gómez¹, S. Santos-Mínguez¹, C. Miguel-García¹, S. Tocino-Antonio⁴, A. Zamora-Canovas⁵, P. Ruiz-Sala⁶, M. Peñarrubia⁷, E. Pardal⁸, J. Hernández-Rivas⁹, J. González-Porras¹⁰, R. Benito¹, J. Rivera¹¹, I. García-Tuñón¹, A. Balduini¹², J. Bastida¹³