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ISTH 2022 Congress

July 9-13, 2022. London, England, UK.

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  • Abstract Number: PB0238

    Tapering of trombopoietin receptor agonist in pediatric patients with chronic ITP. Is it posible?

    R. Berrueco1, M. Solsona2, E. Sebastián3, A. Cervera4, A. Sastre5, I. Astigarraga6, B. Argiles7, M. Dasí7, J. Dapena8, E. Monteagudo7

  • Abstract Number: PB0488

    Targeted Factor V replacement during major trauma haemorrhage

    A. Thaventhiran1, J. Lopez-Tremoleda2, K. Brohi2, C. Thiemermann3, R. Davenport4

  • Abstract Number: OC 56.4

    Targeted panel sequencing for identifying new rare genetic variants associated with venous thromboembolism (VTE): application to 128 patients with unprovoked VTE and negative thrombophilia screening

    P. Suchon1, N. Saut2, M. Alessi3, D. Tregouet4, P. Morange5

  • Abstract Number: PB0345

    Targeting platelet Glycoprotein VI with Glenzocimab: a novel mechanism of inhibition

    P. Billiald1, A. Slater2, M. Pugnière3, I. Jiacomini4, M. Welin5, N. Rose5, E. Toledano6, D. François6, S. Watson7, M. Jandrot-Perrus8

  • Abstract Number: PB0088

    Telehealth and Health Outreach Mode of HealthCare Delivery in patients with Bleeding Disorders: Experience from a Tertiary Care Centre during COVID-19 pandemic

    M. Saleh1, v. Mohammed2, A. AlJefri2, A. Alkofide2, B. abdo2, B. Safi2

  • Abstract Number: OC 13.3

    Temporal changes in coagulation, endothelial dysfunction and fibrinolysis biomarkers are associated with illness severity in patients with COVID-19: Canadian COVID-19 Prospective Cohort Study (CanCOV)

    G. Juneja1, M. Castelo2, C. Yeh1, V. Sabourin1, B. Hansen3, A. Cheung3, M. Herridge3, P. Kim1

  • Abstract Number: PB0367

    Temporal labelling of ageing platelets in mice indicates differential regulation and retention of granule protein encoding mRNAs

    P. Armstrong1, N. Kirkby2, C. Gutmann3, H. Allan4, A. Joshi3, M. Crescente5, J. Mitchell2, M. Mayr3, T. Warner1

  • Abstract Number: PB1078

    TFTEM – a New Reagent to Detect Direct Oral Factor Xa Inhibitors on ROTEM Devices

    M. Schwaiger, A. Kholmukhamedov, R. Al Sawad, R. Bottenus

  • Abstract Number: PB1334

    The (T) thrombosis (I) in patients with (L) lower (L) limb (I) injuries (R) requiring (I) immobilisation (TILLIRI) study: A prospective observational multicentre study – Early Results

    T. O Halloran1, M. Watts1, S. Egan2, M. O’Donoghue3, B. Bleach4, T. Breslin5, M. Alshafie5, J. O'Driscoll5, B. Nemeth6, S. Cannegieter7, S. O'Rourke8, M. Barlow8, N. Salter9, A. Wakai10, N. O'Connell11, M. Nolan12, M. Crowley13, A. Burke14, M. Maxwell15, D. O Keeffe1

  • Abstract Number: PB0432

    The ADAMTS-13 / von Willebrand factor (VWF) ratio as a prognostic biomarker for the development of portal vein thrombosis (PVT) in patients with compensated cirrhosis.

    R. De Cristofaro1, S. Lancellotti2, M. Sacco1, M. Tardugno1, A. De Magistris3, M. Basso4, M. Pompili5, F. Ponziani5, F. Santopaolo5, A. Grieco5

  • Abstract Number: OC 58.1

    The amyloid peptide β increases endothelial permeability in a NADPH oxidase 1-dependent manner: a link between Alzheimer’s Disease and neurovascular inflammation

    A. Tarafdar1, N. Wolska2, C. Krisp3, H. Schlüter2, G. Pula4

  • Abstract Number: PB0382

    The antibody JAQ1 binds to both human and mouse GPVI but differently affect their function and in vivo depletion.

    S. Navarro1, H. Brown2, J. Heemskerk3, M. Kuijpers4, D. Stegner5, B. Nieswandt6

  • Abstract Number: PB0553

    The antithrombotic protein C activator thrombin mutant W215A/E217A (AB002, E-WE) is slowly inhibited by the endogenous thrombin inhibitors antithrombin, protein C inhibitor, and heparin cofactor II

    B. Markway1, M. Carris2, N. Verbout1, M. Wallisch1, C. Lorentz1, A. Gruber1, E. Tucker1

  • Abstract Number: PB0603

    The assessment of ROTEM test in patients with critical form of COVID-19

    V. Popov1, L. Iliescu2, A. Badea1, C. Pirvu2, A. Grigorie1, O. Constantin1, M. Badoiu Niculae1, A. Calen1, A. Nichita2, A. Rus1, M. Andreescu1

  • Abstract Number: PB1216

    The association between vitamin D and disease activity in adult patients with chronic primary immune thrombocytopenia

    K. Van Eeden1, W. van Dijk2, R. Schutgens3

  • Abstract Number: PB1159

    The Atlanta Study: Emicizumab and simoctocog alfa in previously untreated/minimally treated patients and in patients with inhibitors

    R. Sidonio1, M. Callaghan2, M. Manco-Johnson3, S. Meeks4, A. Shapiro5

  • Abstract Number: PB0389

    The C-Type Lectin CD93 Regulates Platelet Activation Induced by PAR4 Stimulation

    S. Trivigno1, M. Vismara2, M. Zarà3, L. Galgano1, S. Carnevali Carlino2, I. Canobbio2, F. Galvagni4, M. Orlandini4, M. Torti5, G. Guidetti2

  • Abstract Number: PB0628

    The characterization of clot-fibrinolysis waveform analysis and the investigation of usefulness in critical care patients with enhanced or suppressed fibrinolysis

    O. Kumano1, T. Tsuchida2, M. Hayakawa2

  • Abstract Number: OC 36.1

    The CLEC4M locus participates to the regulation of FV plasma levels: insights from a new genome-wide association study conducted in 4,373 participants

    D. Tregouet1, A. Martinez-Perez2, M. Kleber3, A. van Hylckama Vlieg4, M. Germain5, J. Deleuze6, J. Souto2, N. Smith7, M. Sabater-Lleal8, G. Delgado9, F. Rosendaal10, P. Morange11

  • Abstract Number: VPB0995

    The clinical use of idarucizumab for dabigatran reversal in Aragón (Spain), new data

    S. Angós Vázquez1, A. Ortiz Lopez2, N. Gemperle Ortiz3, I. Rivas Estabén4, M. Moles Guerrero1, V. Murillo Cortés1, O. Gavín Sebastian1, M. Dobón Rebollo3, J. Calvo Viñas5, I. Cuesta Gallardo6, P. Paul Vidaller7, M. Paricio Moreno8, L. Palomera Bernal1

  • Abstract Number: PB0425

    The CLUES Study: A Critical Look at Understanding the Emotional Suffering of Blood Clot Survivors

    R. Rosovsky1, W. Robertson2, F. Klok3

  • Abstract Number: PB0522

    The Combination of Lipocalin-2 and Calprotectin Improves Risk Assessment in Advanced and Early Peripheral Arterial Disease

    G. Saenz-Pipaon1, S. Ravassa1, K. Lawaetz-Larsen2, E. Martínez-Aguilar3, J. Orbe4, J. Rodriguez5, L. Fernandez-Alonso3, A. Gonzalez5, J. Martin-Ventura6, J. Páramo7, J. Lindholt2, C. Roncal5

  • Abstract Number: PB1290

    The contribution of peptidylarginine deiminase 4 and NETs to a dysregulated VWF/ADAMTS13 axis in Staphylococcus aureus bacteremia in patients

    C. Martens1, M. Peetermans2, M. Jacquemin3, P. Verhamme4, K. Martinod1

  • Abstract Number: VPB0137

    The difference of coagulation indicators between COVID-19 and Dengue Haemorrhagic Fever in Children: A Single-Centre Study

    S. Tatura1, S. Gunawan2, R. Sugoro3

  • Abstract Number: PB0415

    The effect of a gut microbiome intervention on antiphospholipid syndrome: the ROMAS study

    V. Jansen1, D. van Mourik1, K. van Bergen en Henegouwen1, T. Noordermeer2, M. Limper3, R. Urbanus2, S. Middeldorp4, T. van Mens1

  • Abstract Number: VPB0171

    The effect of anti-coagulant agents against in vitro hemophilia A plasma coagulation and fibrinolysis potential in the presence of emicizumab

    T. Onishi1, S. Harada2, H. Shimo3, Y. Tashiro2, T. Soeda2, K. Nogami4

  • Abstract Number: PB1095

    The Effect of Aqueous Chromolaena odorata (Acheampong leaf) extract use on Coagulation test parameters in Vitro

    D. OFOSU1, A. Asamoah2, R. Tuekpe Mawuli2, A. Addai3, E. Takyi Kofi3, E. Opoku Addo3

  • Abstract Number: PB0892

    The effect of PCSK9 on platelet aggregation and on the inflammatory activation of endothelial cells

    A. Tsouka1, A. Tselepis2

  • Abstract Number: PB0183

    The Effect of Regulatory T Cell Functions and Cytokines on the Development of Inhibitor

    S. Genc1, E. Akkaya2, B. Koc3, O. Zulfikar4

  • Abstract Number: OC 06.1

    The effect of rituximab on antiphospholipid antibody titers in patients with Antiphospholipid Syndrome.

    K. Youkhana1, H. Heiling1, A. Deal2, S. Moll1

  • Abstract Number: PB0975

    The effect of rivaroxaban on the diagnostic value of D-dimer

    H. Mohamad1, S. Vikum2, C. Jørgensen3, M. Tavoly4, L. Garabet5, W. Ghanima6

  • Abstract Number: PB1104

    The effect of sample transportation on microparticle production measured in vitro using a procoagulant phospholipid activity assay.

    M. Sharp1, J. Griffin2, S. MacDonald1

  • Abstract Number: PB0020

    The Effects of Hyperglycemia on Endothelial Activation and the Initiation of Atherosclerosis

    L. Mastrogiacomo1, R. Ballagh2, D. Venegas-Pino2, G. Werstuck3

  • Abstract Number: PB0356

    The emerging role of Kupffer cells in thrombopoietin generation

    D. Karakas1, J. Li2, H. Ni3

  • Abstract Number: OC 19.3

    The endothelial inflammatory repertoire: a multi-omics delineation of cytokine-induced endothelial inflammation states

    S. Groten1, E. Smit1, E. Janssen1, B. van den Eshof1, F. van Alphen1, C. van der Zwaan1, A. meijer2, A. Hoogendijk1, M. van den Biggelaar1

  • Abstract Number: PB1180

    The ex vivo effects of varying factor VIII concentration on clot formation and structure in Haemophilia A patients

    C. Morris1, J. Bester2, J. Potgieter2

  • Abstract Number: OC 66.1

    The Factor XII-uPAR Axis Drives Ovarian Cancer Maintenance and Progression

    K. Bane1, A. Gandhi2, J. McAnulty2, D. Bohinc3, A. DiFeo2, E. Stavrou4

  • Abstract Number: VPB1047

    The FV-A2086D mutation results in impaired anticoagulant function.

    N. Shimonishi1, K. Ogiwara2, K. Nogami1

  • Abstract Number: PB0335

    The GFI1B c.503G>T; p.(Cys168Phe) variant – a diagnostic conundrum.

    M. Mitchell1, R. Wheeler2, J. Cutler2

  • Abstract Number: OC 41.2

    The GPIbα intracellular tail is important for VWF-mediated platelet signaling events that promote platelet/neutrophil interactions under flow

    A. Constantinescu-Bercu1, J. Lee1, A. Petri1, P. Mangin2, K. Vanhoorelbeke3, J. Crawley1, I. Salles-Crawley4

  • Abstract Number: PB0890

    The heparan sulfate proteoglycan perlecan induces conflicting patterns of thrombus formation upon activation of GPVI: a novel role in thrombus stability?

    I. Provenzale1, J. Gibbins2, J. Heemskerk3, P. van der meijden4, C. Jones2

  • Abstract Number: PB1052

    The higher activity of baboon versus human tissue factor implicates an extended exosite region

    V. Zeng, F. Birkle, J. Morrissey

  • Abstract Number: OC 39.5

    The immediate effect of COVID-19 vaccination on anticoagulation control in adolescents and young adults using vitamin K antagonists.

    C. Visser1, A. Yousefi2, M. Nierman3, M. Huisman4, A. Gulpen5, C. van Ommen6, M. Kruip7

  • Abstract Number: PB0602

    THE IMPACT OF COVID-19 PANDEMIC ON THE HEALTH AND LIFESTYLE HEMOPHILIA PATIENTS IN A LOW RESOURCED COUNTRY AND ITS EFFECT ON THEIR ACTIVATED PARTIAL THROMBOPLASTIN TIME (aPTT) RESULTS

    D. OFOSU1, C. Obirikorang2, R. Ngala3, A. Asamoah4, R. Tuekpe Mawuli4, E. Owusu5, S. Quarshie4, A. Owusu Banahene4, M. Titus4, G. Asare Amponsah4

  • Abstract Number: PB0878

    The Impact of Dual Anti-platelet, Anti Coagulation Therapy on Hemostatic Plug Structure and Function

    C. Mansi1, J. Severa2, T. Marar2, T. Stalker2

  • Abstract Number: PB1008

    The impact of hematocrit on postoperative bleeding risk in patients undergoing robotic radical prostatectomy

    S. Arcudi1, A. Artoni2, E. De Lorenzis3, C. Silvani4, F. Spanu5, S. Villa6, M. Capecchi7, E. Montanari3, F. Peyvandi8

  • Abstract Number: OC 47.5

    The impact of N-linked glycosylation in C1 domain of FVIII on immunogenicity

    M. Fan1, S. Wang2, J. Zhang3, X. Cai1, T. Chao1, L. Li2, W. Xiao3, B. Konkle4, C. Miao1

  • Abstract Number: VPB0132

    The Impact of Sex on D-Dimer Levels and Disease Outcomes in Hospitalized COVID-19 Patients

    O. Saville1, Y. Tera2, Y. Deng3, M. Elbatarny4, M. Othman2

  • Abstract Number: PB0923

    The incidence and risk factors of thrombotic complications in patients with diffuse large B cell lymphoma at Trang Hospital.

    S. Jutiamornlerd

  • Abstract Number: OC 25.5

    The Incidence and Risk Factors of Venous and Arterial Thrombosis in Ovarian Cancer Patients- Results from a Population Database

    A. Lukey1, S. Penfound2, J. Hodgson2, W. Hopman2, G. Hanley1, M. Othman2

  • Abstract Number: VPB1169

    The Incidence of FV Leiden and MTHFR Gene Mutations in Patients with Hemophilia A and B in the North-Western Region of Russia

    V. Soldatenkov1, O. Soldatenkova2, K. Komissarov2, V. Burakov2, N. Saltykova2, L. Papayan3, N. Silina2, S. Kapustin1, O. Smirnova4, A. Titov2

  • Abstract Number: PB1036

    The increase in plasma cell-free DNA in patients with venous thromboembolism is independent of DNaseI activity

    R. Herranz1, J. Oto1, E. Plana2, F. Cana3, A. Fernández-Pardo3, F. Ferrando4, A. Cid4, S. Bonanad5, P. Medina3

  • Abstract Number: PB1407

    The increased risk of venous thromboembolism (VTE) in obese pregnant women is due to more prolonged exposure to a procoagulant state.

    S. McNeill1, F. Jordan2, V. Gibson3, D. Freeman2, C. Bagot4

  • Abstract Number: PB0727

    The induction of Tregs by aPC depends on metabolic reprogramming and reduced αKG levels

    D. Gupta1, A. Elwakiel2, S. Ranjan2, M. Pandey2, S. Krishnan3, R. Henschler4, S. Kohli1, B. Isermann1

  • Abstract Number: PB0863

    The influence of hemolysis on platelet reactivity in patients undergoing aortic valve replacement surgery.

    S. Sánchez1, A. García1, F. García1, N. Marín2, J. García-Estañ2, J. Moraleda1, D. Iyu2

  • Abstract Number: PB0579

    The Influence of Plasma Prekallikrein Oligonucleotide Antisense Therapy on Coagulation and Fibrinolysis Assays

    L. Fijen1, J. Meijers2, L. Bordone3, R. Petersen4, M. Levi4, D. Cohn4

  • Abstract Number: PB0669

    The Interobserver and Intraobserver Agreements on HEAD-US in the assessment of Hemophilic Arthropathy

    E. Yılmaz1, Z. Kaya1, H. Satış2, İ. Akdulum3, M. Yazol3, A. Tufan4, Ş. Haznedaroğlu2, O. Konuş Boyunaga3, S. Kirkiz1, Ü. Koçak1

  • Abstract Number: PB0039

    The Key Role of Plasminogen Activator Inhibitor-1 (PAI-1) in the Thrombogenesis Difference in COVID-19-associated Pneumonia Compared to Bacterial Pneumonia

    K. Bielosludtseva1, T. Pertseva2

  • Abstract Number: PB1000

    The Loss of High Molecular Weight Von Willebrand Factor Multimers under Shear Conditions in Sheep is Not Solely ADAMTS13 Dependent

    S. Deconinck1, A. Schelpe2, I. Pareyn1, A. Vandenbulcke1, C. Tersteeg3, S. De Meyer3, K. Vanhoorelbeke3

  • Abstract Number: OC 66.3

    The Lung Pro-thrombotic Niche Drives Cancer-Associated Thromboembolism via Exosomal ITGB2

    S. Lucotti1, Y. Ogitani2, C. Kenific1, L. Bojmar1, M. Cioffi1, P. Lauritzen1, H. Molina3, S. Heissel3, H. Lengel4, X. Jing5, H. Zhang1, I. Matei1, E. O'Reilly4, W. Jarnagin4, D. Jones4, J. Bussel1, D. Kelsen4, J. Bromberg4, D. Simeone5, D. Lyden1

  • Abstract Number: PB0718

    The Management of Craniopharyngioma in a Child with Severe Factor XI Deficiency

    A. UNUVAR1, S. KARAMAN2, O. KULELI2, A. SENCER3, D. DEMIRKOL4, G. TANYILDIZ2, M. BILICI2, G. GENCAY5, Z. KARAKAS2, D. TUGCU2

  • Abstract Number: PO0061

    The Management of Thrombotic Complications in Oncological Patients

    V. Musteata1, S. Pinzari2, M. Popescu3, L. Musteata3, V. Tomacinschii3, O. Privalova2

  • Abstract Number: VPB1351

    The Manipal Deep Venous Thrombosis Registry: Clinical Characterization, Treatment Patterns and 2-year Outcomes of DVT Patients in India

    A. Singh1, D. Shivakumar2, M. Virdiana2, A. Srikanth2, T. Devasia3

  • Abstract Number: OC 17.2

    The measurement of a next-generation FVIII Mimetic, Mim8, using tissue factor triggered calibrated automated thrombography

    A. Bowyer1, S. Kitchen2, M. Ezban3

  • Abstract Number: PB0763

    The mTOR Pathway in Platelets Contributes to the Pathophysiology of Experimental Cerebral Malaria

    I. Portier1, F. Denorme1, K. Queisser1, Y. Kosaka1, A. Petrey1, G. Zimmerman1, C. Morrell2, R. Campbell1, M. Rondina1

  • Abstract Number: PB1132

    The new era of Haemophilia in a Comprehensive Hemophilia Treatment Center in Mexico

    A. Gonzalez1, T. Garcia-Lee2, G. Ignacio1, S. Quintana3

  • Abstract Number: PB0719

    The novel bispecific antibody HMB-001 enhances the haemostatic response in models of Glanzmann Thrombasthenia by targeting FVIIa to activated platelets

    M. Zivkovic1, P. Gandhi2, H. Ostergaard2, E. Olsen2, C. Rea3, B. Sorensen4, J. Faber2, R. Schutgens1, S. Bjorn2, R. Urbanus5

  • Abstract Number: PB0917

    The Ottawa Score did not predict recurrent venous thromboembolism in the prospective TROPIQUE cohort study

    C. Frere1, P. Debourdeau2, A. lamblin3, F. Cajfinger4, N. Falvo5, Y. Benhamou6, M. Sevestre7, D. Farge8

  • Abstract Number: PB1038

    The participation of plant heparinoids in the regulation of blood clotting

    E. Maystrenko, M. Lyapina, M. Kalugina, L. Lyapina

  • Abstract Number: PB1242

    The phenotypic and genetic heterogeneity of Hermansky-Pudlack Syndrome

    F. Santos1, M. Coutinho1, C. Monteiro2, M. Pereira3, R. Matos1, A. Gonçalves4, E. Cruz5, R. Santos6, S. Morais7

  • Abstract Number: PO0023

    The potential differential diagnosis value of lymphocyte ratio in patients with cytopenic diseases

    Y. Xu, R. Zhou

  • Abstract Number: PB0853

    The potential of pre-activated platelets to contribute to thrombus formation

    I. De Simone1, C. Baaten2, J. Gibbins3, H. ten Cate4, J. Heemskerk5, C. Jones3, P. van der meijden6

  • Abstract Number: VPB0284

    The potentiality of thromboelastographic examination of newborns with venous thrombosis

    A. Ilyina1, A. Mishchenko2, L. Vorona1, A. Martynov1, E. Akhalova1, A. Rogova1, L. Doronin1, E. Akkuzina1

  • Abstract Number: PB0040

    The Predictive Role of Plasminogen Activator Inhibitor-1 (PAI-1) in the COVID-19-associated Pneumonia

    K. Bielosludtseva1, T. Pertseva2

  • Abstract Number: VPB1218

    The predictive value of platelet specific antibodies for the first-line treatment effect in newly diagnosed pediatric ITP

    S. dong

  • Abstract Number: PB1329

    The predictive value of pulmonary infarction in patients with acute pulmonary embolism on persistent symptoms and adverse events

    F. Kaptein1, L. Kroft2, L. van Dam3, J. Stöger1, M. Ninaber1, M. Huisman4, F. Klok5

  • Abstract Number: OC 03.2

    The Prekallikrein and Factor XII Heavy Chains in Surface-Independent Reactions.

    P. Srivastava1, S. Kumar1, A. Shamanaev2, M. Sun3, D. Gailani4

  • Abstract Number: PB1410

    The prenatal assessment of congenital bleeding disorder in carrier women with menorrhagia

    K. Perveen1, M. Borhany1, M. Abid1, T. Shamsi2

  • Abstract Number: PB0922

    The Prevalence of Thrombophilia in Patients with Cancer Associated Thromboembolism

    J. Hirmerová1, I. Šubrt2, Z. Hajšmanová3

  • Abstract Number: VPB0747

    The Prospective Advances of von Willebrand Factor, ADAMTS13, and Factor VIII in Severe Malaria: A Systematic Review

    B. Putra1, F. Putra2

  • Abstract Number: PB0823

    The rare VWF non-canonical splice-site variant, c.8155+6T>A, causes type 3 von Willebrand disease in homozygosity and results in perinuclear retention of VWF in endothelial cells

    M. Sims1, F. Burden1, J. Collins1, P. North2, L. Stefanucci1, A. Dinan1, S. Sivapalaratnam3, D. Hart4, M. Laffan5, W. Ouwehand6, S. Shapiro7, M. Frontini2

  • Abstract Number: VPB0843

    The ratio of von Willebrand factor activity to antigen in newly diagnosed essential thrombocythemia

    K. Yokoyama

  • Abstract Number: VPB1219

    The relationship between platelet specific antibodies and the severity of newly diagnosed pediatric ITP

    S. dong

  • Abstract Number: PB0767

    The Relevance of Thromboinflammatory Biomarkers and their Relationship with Circulating Glycosaminoglycans in End-Stage Renal Disease Patients

    M. Allen1, V. Bansal2, F. Siddiqui2, D. Hoppensteadt3, E. Krupa2, B. Kantarcioglu4, J. Fareed3

  • Abstract Number: OC 09.1

    The rich inner life of a thrombus – “next generation” analysis of platelet activity during thrombus formation in vivo

    P. Larsson1, V. Tarlac2, A. McGovern3, J. Nunez-Iglesias4, L. Faxälv5, S. Cody6, J. Hamilton2, N. Boknäs7

  • Abstract Number: OC 42.1

    The risk of incident venous thromboembolism attributed to overweight and obesity: The Tromsø Study

    T. Frischmuth1, B. Tøndel2, S. Brækkan3, J. Hansen3, V. Morelli4

  • Abstract Number: OC 54.5

    The risk of venous thromboembolism after minor surgical procedures: A population-based case-control study

    M. Smeets1, C. Touw2, F. Rosendaal3, B. Nemeth4, S. Cannegieter1

  • Abstract Number: OC 35.2

    The role of Adenylyl Cyclase 6 in platelet cyclic-AMP signalling

    B. Webb, M. Hindle, L. Cheah, N. Turner, K. Naseem

  • Abstract Number: PB0916

    The role of anticoagulation in the management of tumour thrombosis: A single centre retrospective study

    U. Faruqi1, R. Darroch2, H. Verma2, G. Bahra3, M. Flynn2, A. Danaee2

  • Abstract Number: VPB1285

    The Role of Endothelial Colony-Forming Cells in Acute Deep Vein Thrombosis

    L. Silva1, S. Montalvão2, S. Huber3, S. Soares3, A. Lemos Junior3, O. Camargo-Junior4, C. Simões4, M. Abreu4, E. de Paula5, J. Annichino-Bizzacchi6

  • Abstract Number: PB1262

    The Role of Endothelial Glycocalyx Degradation in COVID-19

    H. Jerndal1, C. Ahlm2, A. Fors Connoly2, J. Normark3

  • Abstract Number: PB1287

    The role of extracellular vimentin in fibrin formation

    M. Cruz1, M. Martinez-Vargas1, L. Brubaker2, A. Cebula2, A. Yee3, R. Rumbaut2

  • Abstract Number: PB1256

    The role of FSAP in regulating endothelial permeability

    X. Cui1, B. Stavik2, P. Sandset3, S. Kanse4

  • Abstract Number: VPB0374

    The role of miRNAs in regulation of platelet activity – a bioinformatic analysis

    Z. Wicik1, C. Eyileten1, D. Jakubik1, J. Jarosz-Popek1, M. Wolska2, A. Nowak1, D. Keshwani1, D. Von Lewinski3, H. Sourij3, J. Siller-Matula4, M. Postula1

  • Abstract Number: OC 18.4

    The role of neutrophil extracellular traps (NETs) in lower extremity artery disease (LEAD)-specific thrombosis

    M. Thakur1, N. Angliker2, M. Siegrist3, M. Kuijpers4, M. Schindewolf3, I. Baumgartner3, Y. Döring5

  • Abstract Number: PB0774

    The role of platelets in chemotherapy-associated steatohepatitis

    P. Spitzenstätter1, J. Sturm1, M. Derler1, D. Pereyra2, P. Starlinger3, A. Assinger4, M. Mussbacher1

  • Abstract Number: PB0768

    The role of platelets in ER stress-induced hepatic steatosis

    M. Derler1, W. Schrottmaier2, M. Salzmann2, G. Schoiswohl1, J. Schmid3, A. Assinger2, M. Mussbacher1

  • Abstract Number: PB0272

    The role of procoagulant microparticles in hemostasis of patients with hemolysis

    E. Seregina1, E. Lipets1, A. Poletaev1, A. Ignatova1, Y. Chuiko2, T. Vuimo3, F. Ataullakhanov4, N. Smetanina4

  • Abstract Number: VPB0941

    The Role of Selectins in Development of Acute Pulmonary Embolism in Cancer Patients.

    I. Darwish1, B. Kantarcioglu2, A. Darki3, F. Siddiqui4, O. Iqbal4, D. Hoppensteadt3, J. Fareed3

  • Abstract Number: PB0332

    The role of thrombopoietin receptor agonists in preventing surgical bleeding in patients with inherited thrombocytopenia

    M. Carneiro1, E. Silva1, A. Ferreira2, M. Oliveira1, M. Coutinho1, E. Cruz3, S. Morais4

  • Abstract Number: PB0803

    The role of VWF-ADAMTS13 axis in cisplatin-induced acute kidney injury in mice

    S. Senzaki1, A. Kakiwaki2, A. Sawa2, N. Nishimura2, R. Yoneima2, H. Kawashima2, S. Ono2, K. Yoshimoto2, A. Sakata3, K. Tatsumi4, M. Sugimoto2, M. Shima5, K. Nishio2

  • Abstract Number: OC 10.4

    The Role of α-Synuclein and Cysteine String Protein-α in Platelet Function

    A. Smith1, L. Omali2, S. Joshi2, S. Whiteheart3

  • Abstract Number: PB0495

    The safety and efficacy of direct oral anticoagulants for atrial fibrillation in patients affected by hematologic malignancies: a single-center experience

    A. Serrao1, M. Chavez Orellana2, G. Assanto3, R. Mormile3, E. Baldacci3, C. Santoro4, A. Chistolini2

  • Abstract Number: OC 15.2

    The SAXOPHONE Study; A Multi-Center, Multi-National Randomized Trial of Apixaban versus Standard of Care Anticoagulation for Thromboprophylaxis in Children with Congenital or Acquired Heart Disease

    R. Payne1, K. Burns2, A. Glatz3, C. Male4, A. Donti5, L. Brandão6, G. Balling7, C. VanderPluym8, F. Bu'Lock9, L. Kochilas10, B. Stiller11, J. Cnota12, A. Buendia13, O. Rahkonen14, O. Wheaton15, A. Reedy16, J. Dyme17, L. Carlson16, C. Crevar17, P. Monagle18

  • Abstract Number: OC 14.5

    The severe thrombophilic state associated to inferior vena cava agenesis: data from a multicentre cohort of 178 patients from the IVC Agenesis Study Group Registry

    C. Bravo-Pérez1, A. Blanco1, N. Revilla2, S. Asenjo3, S. Bonanad4, N. Castro5, S. Marcellini6, P. López-Sala7, D. Palomino8, M. Infante9, M. Corral10, J. Rodriguez-Sevilla11, A. Rodríguez-Alen12, T. Sevivas13, D. Morello14, V. Vicente15, M. Lozano15, M. de la Morena-Barrio15, J. García-Santos1, J. Corral15

  • Abstract Number: PO0007

    The six episodes of ischemic stroke during 16 years. Clinical case in a young woman.

    A. Ter-Grigoryan1, N. Sargsyan2, A. Harutyunyan3, I. Karapetyan4, Y. Hovhannisyan5, G. Tamamyan6, H. Khachatryan7

  • Abstract Number: OC 36.5

    The TFPIα C-terminal tail is essential for the synergistic enhancement of TFPIα mediated inhibition of FXa by protein S and FV-short.

    M. Gierula1, V. Noakes2, I. Salles-Crawley3, J. Crawley2, J. Ahnström2

  • Abstract Number: PB1143

    The Thrombin Generation Test represents a better tool than Factor VIII levels to assess the risk of bleedings in patients with hemophilia A

    A. Bernardo1, I. Soto2, L. Gutiérrez3, A. Caro2, D. Martínez-Carballeira2, J. Corte Buelga4, S. Vázquez2, C. Palomo-Antequera5, A. Andreu6, A. Fernández-Pardo7, J. Oto8, P. Medina7

  • Abstract Number: OC 27.1

    The type and frequency of bleeds in 870 children with severe hemophilia A and B on primary prophylaxis: Data from the PedNet study group

    H. van den Berg1, M. Alvarez Roman2, M. Carcao3, H. Chambost4, K. Fischer5, N. Grentenkort-Andersson6, G. Kenet7, C. Königs8, R. Ljung9, C. Male10, J. Motwani11

  • Abstract Number: PB0563

    The ultra-sensitive Nijmegen Inhibitor Assay detects very low-titer factor VIII inhibitors.

    L. Valke1, M. Verhagen2, B. Mulders3, R. Polenewen3, S. Schols4, W. van Heerde5, D. Meijer6

  • Abstract Number: PB0859

    The uptake and utilisation of fatty acids by platelets.

    M. Hindle, K. Naseem

  • Abstract Number: PO0004

    The use of anticoalulants is safety. Myth or reality?

    E. Shchegov

  • Abstract Number: VPB0281

    The use of Apixaban for thromboprophylaxis and treatment in children with cardiac disease younger than 6 months of age

    P. Esteso1, R. Kobayashi2, R. Williams3, C. Ventresco2, B. Hawkins2, M. Cetatoui2, J. Esch1, C. VanderPluym4

  • Abstract Number: VPB1376

    The Use of Aspirin Thromboprophylaxis Compared to Alternative Anticoagulants in Elective Total Hip Replacement: A Retrospective Cohort Study

    R. Norman1, J. Kielly2, K. Osei Bonsu3, R. Chitsike4, S. Young5

  • Abstract Number: VPB0234

    The Use of Mixing Tests on Some Prolonged Coagulation Tests Results Generated from Haematology Core Laboratory of Two Tertiary Hospital in Calabar. Cross River State, Nigeria

    D. Okpokam1, H. Ina1, E. Iyamah2, U. Udofia1, A. Emeribe1

  • Abstract Number: PB0297

    The use of Obinutuzumab and Ofatumumab in the treatment of immune Thrombotic Thrombocytopenic Purpura

    A. Doyle1, M. Stubbs2, W. Lester3, W. Thomas4, J. Westwood2, M. Thomas2, C. Percy3, N. Prasannan2, M. Scully2

  • Abstract Number: PB0642

    The use of plasminogen activator inhibitor-1 specific Affimers as a tool to modulate fibrin clot properties and thrombosis risk

    R. Altalhi1, C. Tiede1, F. Phoenix1, D. Tomlinson1, K. Naseem1, R. Ajjan1, N. Pechlivani2

  • Abstract Number: VPB1427

    The use of rotational thromboelastometry in the management of thromboprophylaxis in pregnancy

    L. Stanciakova1, M. Dobrotova2, P. Holly3, J. Zolkova2, L. Vadelova4, I. Skornova2, J. Ivankova3, M. Brunclikova2, M. Grendar5, J. Danko6, P. Kubisz2, J. Stasko2

  • Abstract Number: PB0965

    The Use of Transthoracic Echocardiography in Adults Hospitalized with Acute Pulmonary Embolism

    B. Azad1, K. Steckham2, T. Azad3, C. Ainsworth2, L. Lau4, S. Mithoowani2, D. Siegal5

  • Abstract Number: VPB1377

    The use of warfarin in patients with heart diseases in Brazil and factors associated with non-adherence to treatment

    W. Freitas Nunes De Sousa1, N. Sernizon Guimarães1, R. Pedra De Souza1, M. Da Costa Rocha1, A. De Oliveira Magalhães Mourão1, K. Braga Gomes Borges1, C. Margotto Bartollo1, M. Praxedes2, M. Parreiras Martins1

  • Abstract Number: PB0712

    The utility of bleeding assessment tools in fibrinogen deficiencies

    S. Mohsenian1, O. Seidizadeh2, R. Palla3, M. Jazebi4, A. Azarkeivan5, S. Moazezi4, M. baghaipour4, M. Menegatti6, F. Peyvandi7

  • Abstract Number: PB1099

    The validation of linear One-Stage Clotting Assays (OSCA) using fully automated Multi-Dilution Analysis (MDA) in the quantification of factor activity

    K. Ram1, S. Platton2, R. Narisada3

  • Abstract Number: PB1080

    The validation of mixing test-specific cut-off in lupus anticoagulant mixing test interpretation for multiple reagents

    O. Kumano1, G. Moore2

  • Abstract Number: PB0629

    The validation of new global fibrinolysis capacity assays in high tPA concentration situation and the comparison with thromboelastgraphy

    O. Kumano1, T. Tsuchida2, M. Hayakawa2

  • Abstract Number: OC 64.1

    The VarioPath project: Determining effect sizes of pathogenic variants in platelet disorder genes, using clinical data from 0.5M whole exome sequenced UK Biobank participants

    J. Collins1, L. Stefanucci2, M. Sims3, K. Freson4, E. Bruford2, K. Megy2, D. Vuckovic5

  • Abstract Number: PB1328

    The Venous Thrombosis Registry in Østfold Hospital (The TROLL registry); design and cohort description

    C. Jørgensen1, M. Tavoly2, H. Pettersen3, E. Førsund3, C. Roaldsnes3, M. Olsen3, E. Tjønnfjord3, J. Gleditsch4, A. Galovic3, S. Vikum5, S. Brækkan6, W. Ghanima7

  • Abstract Number: OC 67.5

    The Von Clauss Assay Does Not Accurately Measure Total Fibrinogen Levels After Traumatic Injury. Have We Been Thinking About Fibrinogen Replacement All Wrong?

    M. DeBot1, I. Lacroix2, A. D'Alessandro3, E. Moore4, C. Silliman2, A. Sauaia2, T. Schaid5, C. Erickson2, A. Cralley2, M. Cohen2, K. Hansen2

  • Abstract Number: PB0952

    The von Willebrand Factor / ADAMTS13 ratio is a good indicator of venous thromboembolism risk. Results from the RETROVE project.

    D. Llobet1, C. Vallvé2, S. Mojal2, M. Carrasco2, N. Vilalta2, J. Mateo2, J. Millón2, J. Souto3

  • Abstract Number: PB0802

    The VWF Propeptide Is A Novel Component Of Venous Thrombi In A Mouse Model Of DVT

    O. Rawley1, C. Dwyer1, K. Nesbitt1, C. Notley1, A. Michels1, D. Lillicrap2

  • Abstract Number: PB0386

    The WASH-complex subunit Strumpellin regulates integrin αIIbβ3 trafficking in murine platelets

    M. Spindler1, Y. Schurr2, L. Reil2, B. Nieswandt2, L. Machesky3, M. Bender2

  • Abstract Number: VPB0615

    Therapeutic Dose of Enoxaparin Associated with a Better Outcome for COVID-19 Hospitalized Patients

    F. Leite1, S. Ferreira2, À. Leite3

  • Abstract Number: OC 18.1

    Therapeutic potential of CD146 extracellular vesicles for the treatment of atherosclerosis

    C. Dubrou1, M. Blin1, K. Fallague1, R. Bachelier2, C. Chareyre1, S. Robert3, R. Lacroix4, F. Dignat-George5, N. Bardin5, M. Blot-Chabaud1, A. leroyer1

  • Abstract Number: PB0558

    Thigh-tourniquet application during knee arthroscopy does not induce a hypercoagulable state – A randomized trial into the effect of tourniquet use on the coagulation system.

    B. Nemeth1, C. Touw2, S. le Cessie3, R. Onstenk4, V. Wennemers4, P. Haen4, R. van den Wijngaard4, R. van Adrichem5, R. Nelissen6, T. Lisman7, S. Cannegieter8

  • Abstract Number: PB0907

    Three-month outcomes in cancer patients with superficial- or deep vein thrombosis in the lower limbs. Results from the RIETE Registry.

    L. Bertoletti1, P. DEBOURDEAU2, C. FONT3, J. LÓPEZ-NÚÑEZ4, C. GÓMEZ-CUERVO5, I. MAHÉ6, R. Otero-Candelera7, M. ADARRAGA8, P. LÓPEZ-MIGUEL9, M. Monreal10

  • Abstract Number: OC 26.4

    Thrombin and ADP pathways of platelet aggregation are dysregulated in participants with diabetes in the Framingham Heart Study

    M. Chan1, D. Masood1, M. Chen1, F. Thibord2, B. Nkambule3, A. Lachapelle1, J. Cunha4, R. Pashek5, A. Johnson1

  • Abstract Number: PB0219

    Thrombin generation measurement in hemophilia A patients with inhibitors receiving emicizumab prophylaxis

    Y. Dargaud1, C. Escuriola Ettingshausen2, S. Desage3, S. Meunier4, A. Lienhart4

  • Abstract Number: PB0028

    Thrombin generation predicts outcomes in patients with non-traumatic intracerebral hemorrhage

    L. Lóczi1, R. Orbán-Kálmándi2, T. Árokszállási3, M. Héja3, I. Fekete4, K. Fekete4, J. Tóth5, L. Csiba6, Z. Bagoly7

  • Abstract Number: PO0011

    Thrombin generation test in patients with Covid-19

    N. Vorobyeva1, A. Barteneva2

  • Abstract Number: PB1108

    Thrombin Generation Using the ST-Genesia System in a Cohort of Healthy Asian Adults: Absolute and Normalized Values

    B. Fan1, M. Ang2, H. Tan3, J. Boulaire4, T. Chai4, K. Ong5, V. Sampath5, C. SUM2

  • Abstract Number: OC 25.4

    Thrombo-inflammatory biomarkers in pulmonary embolism as stratified in cancer and non-cancer patient groups.

    F. Siddiqui1, A. Darki1, D. Hoppensteadt1, I. Darwish2, B. Kantarcioglu1, A. Tafur3, J. Fareed1, M. Monreal4

  • Abstract Number: VPB0111

    Thrombocytopenia and Thrombosis associated with AstraZeneca ChAdOx1 nCoV-19 Vaccination – results of Australian centralized clinical triage system and functional assay testing system

    V. CHEN1, L. Clarke2, C. Lee3, F. Passam4, D. Donikian5, M. Kondo5, R. Bird6, P. Choi7, I. Tohidi-Esfahani8, D. Pepperell9, C. TAN10, S. Chunilal11, H. Tran12, T. Brighton5

  • Abstract Number: VPB0124

    Thrombocytopenia in COVID-19 patients on ECMO

    C. Jones1, K. Chen1, V. Narendran2

  • Abstract Number: OC 06.4

    Thrombocytopenia in primary antiphospholipid syndrome: Association with prognosis and clinical implications

    Y. Shi1, J. Zhao2, X. Zeng2

  • Abstract Number: PB0100

    Thromboelastography (TEG) as an Outcome Predictor Marker of Covid-19 Patients in Malang Indonesia

    S. Wardhani1, D. Hermanto1, S. Fatonah2, J. Fajar1

  • Abstract Number: PB1388

    Thromboelastography Assessing Coagulation Profile in Young Women Using Hormonal Contraception

    Y. Tera1, Y. Deng2, M. Othman1

  • Abstract Number: PB1014

    Thromboelastography Characteristics in Pediatric Patients on Extracorporeal Membrane Oxygenation (ECMO)

    K. Regling1, K. Cashen2, W. Hollon3, J. Callaghan4, P. Hines5, M. Chitlur1

  • Abstract Number: VPB0129

    Thromboelastography Six: redefining heparin resistance in post COVID syndrome

    J. Payne1, V. Coba2, A. Marrocco2, T. Long2, N. Gupta3, A. Hodari-Gupta2, I. Lopez-Plaza2

  • Abstract Number: PB0093

    Thromboembolism and its Management in Hospitalized COVID-19 Patients Using Modified Caprini Risk Score: A Single Center Experience in Ethiopia

    T. Tadesse1, A. Teklu2, A. Abiye2

  • Abstract Number: VPB0125

    Thromboembolism in COVID-19 patients on ECMO

    C. Jones1, K. Chen1, G. Cheng2, V. Narendran3

  • Abstract Number: VPB1293

    Thromboinflammatory Biomarkers of Cardiorenal Syndrome in Patients Undergoing Maintenance Hemodialysis in End Stage Renal Disease

    P. Karumanchi1, V. Bansal2, F. Siddiqui2, D. Hoppensteadt3, J. Fareed3

  • Abstract Number: PB0259

    Thrombolytic therapy in neonates and children: a twelve-year prospective registry of a single tertiary pediatric center in Argentina.

    C. Cervio1, M. Hepner2, M. Bianco3, R. Escobar4, G. Pieroni2, E. Annetta5, J. Frontroth1, G. Sciuccati3

  • Abstract Number: VPB0646

    Thrombolytic therapy in pulmonary embolism patients with thrombocytopenia: a systematic review

    F. Ata1, W. H. Ibrahim1, M. Affas1, H. Ahmad Khan2, B. Daoudi1, H. Waqas Younas3, Z. Maat1, S. Mohamed1

  • Abstract Number: PB0947

    Thrombophilia Screening in Patients with Ocular Venous Thrombosis

    M. Alrifai1, U. Sachs2, C. Kelm1

  • Abstract Number: PO0074

    Thrombophilic status and reproductive health of women in the Trans-Baikal Territory

    A. Markovsky

  • Abstract Number: OC 59.1

    Thrombopoiesis has a unique lipidomic profile enriched in polyunsaturated fatty acids that facilitates megakaryocyte maturation and platelet production

    M. Barrachina1, G. Pernes2, I. Becker3, D. Freire4, D. Groeneveld5, J. Luyendyk6, P. Meikle2, J. Italiano7, G. Lancaster2, A. Murphy2, K. Machlus8

  • Abstract Number: OC 73.3

    Thrombopoietin receptor agonists (TPO-RAs) in older patients with primary immune thrombocytopenia (ITP): effective and safe? Real World Data from the UK adult ITP registry.

    P. Raheja1, H. Miah2, A. Miah1, L. Taylor1, T. Biss3, G. Evans4, M. Scully5, J. Hermans6, S. Marshall7, M. Kilner8, R. Rayment9, L. Robinson10, S. Johns11, C. Rinaldi12, H. Jackson13, S. Ackroyd14, A. Newland1, D. Provan1, N. Cooper15, V. McDonald16

  • Abstract Number: PB1355

    Thromboprophylaxis during lower limb immobilisation after injury – a review of 2 years’ practice at King’s College Hospital, London.

    E. Marrinan1, V. Speed2, G. Giron3, L. Georgiou4, R. Harris1, M. Al-Agil1, L. Roberts1, R. Patel2, R. Arya2, J. Czuprynska1

  • Abstract Number: PB0066

    Thromboprophylaxis outcome in childhood SARS-CoV-2 infection: A single-center experience

    M. Karimi1, A. Sanaei Dashti2, S. Haghpanah2, Y. Mansoori3, T. Zarei3, A. Amanati2, M. Bordbar3

  • Abstract Number: OC 61.2

    Thrombosis and major bleeding in patients with severe COVID-19 supported by extracorporeal membrane oxygenation (ECMO)- multicentre observational study in UK

    D. Arachchillage1, I. Rajakaruna2, I. Scott3, M. Laffan4, S. Ledot5, R. Jooste6, A. Vuylsteke6, Y. Hakeem7

  • Abstract Number: PB0271

    Thrombosis risk in children with acute lymphoblastic leukimia during the therapy

    E. Seregina1, L. Zharikova2, N. Trubina2, M. Korsantiya2, M. Gracheva2, A. Poletaev2, T. Vuimo2, J. Rumyantseva2, F. Ataullakhanov3, A. Karachunsky2

  • Abstract Number: VPB0618

    Thrombosis-related circulating miR-16-5p is associated with disease severity in patients hospitalised for COVID-19

    C. Eyileten1, Z. Wicik1, S. Simões2, D. Martins-Jr3, D. Keshwani1, A. Shahzadi4, J. Jarosz-Popek1, M. Wolska5, K. Klos6, W. Wlodarczyk6, D. Soldacki7, A. Chcialowski6, J. Siller-Matula8, M. Postula1

  • Abstract Number: OC 08.2

    Thrombotic and Bleeding Complications in Paediatric Inflammatory Multisystem Syndrome Temporarily Associated with COVID-19 (PIMS-TS) in Children: a Systematic Review

    A. Al-Huniti1, S. Renzi2, S. Ali3, K. Langenberg-Ververgaert4, R. Laxer5, L. Brandão6

  • Abstract Number: VPB1349

    Thrombotic events as a manifestation of vasculitis/vasculopathy induced by cocaine adulterated with levamisole in a Colombian cohort.

    M. Plaza1, T. Urrego2, A. Restrepo3, C. Muñoz1

  • Abstract Number: VPB0438

    Thrombotic events of the spleno-portal axis in pre and post liver transplantation

    A. Ortiz Lopez1, M. Hernández Aínsa2, I. Rivas Estabén3, S. Angós Vázquez4, N. Gemperle Ortiz4, M. Moles Guerrero4, V. Murillo Cortés4, s. Lorente Pérez4, m. Dobón Rebollo4, L. Palomera Bernal4, O. Gavín Sebastian4

  • Abstract Number: PB0954

    Thrombotic profile according to antithombin deficiency and SERPINC1 gene analysis: a French retrospective cohort study.

    L. Khider1, M. DELRUE2, T. Mirault1, N. Gendron3, O. Sanchez4, B. Planquette5, L. Darnige6, S. Gandrille6, A. STEPANIAN7, D. Smadja8, E. Messas9, V. SIGURET10, L. Mauge11

  • Abstract Number: VPB0531

    Thrombotic state of readiness with increase of physical activity

    A. Blazhko

  • Abstract Number: VPB0312

    Thrombotic thrombocytopenic purpura in adult-onset Still’s disease

    R. Ben Salah1, y. bouattour2, A. Ben Mefteh3, M. Chaari4, Z. bAHLOUL5

  • Abstract Number: VPB0311

    Thrombotic Thrombocytopenic Purpura mimicking acute Ischemic stroke

    A. Aribandi1, C. Ranjith2, K. Ashok1, R. Gottipati3

  • Abstract Number: OC 26.5

    Thyroid hormones and analogues promote the acute release of platelets from megakaryocytes: from blood donor biology to the production of platelets in vitro

    H. Foster1, N. Herbert2, A. Waller1, C. Di Buduo3, J. Fang4, A. Schmidt5, D. Howard1, M. Taimoor1, T. Moreau6, A. Meuller1, A. Evans1, R. Biswas7, E. Turro8, R. Fischer9, D. Wilcox10, K. Hoffmeister11, A. Balduini12, C. Ghevaert13

  • Abstract Number: PB0378

    Ticagrelor enhances platelet TP receptor surface expression in patients due to P2Y12 / TP dimerization

    M. Keith1, J. Hutchinson2, J. Khalil1, M. Aungraheeta3, S. Mundell1

  • Abstract Number: PB0762

    Ticagrelor prevents infective endocarditis by mitigating Staphylococcus aureus virulence

    N. Jacques1, S. Meyers2, K. Leeten1, M. Lox3, M. Debuisson1, P. Delvenne4, A. Nchimi1, M. Kuijpers5, T. Vanassche6, K. Martinod7, P. Verhamme3, P. Lancellotti8, C. Oury1

  • Abstract Number: OC 14.1

    Time trends in prognosis of pulmonary embolism in The Netherlands (2013-2018)

    Q. Chen, N. van Rein, S. Cannegieter

  • Abstract Number: PB1033

    Tissue factor (TF) in peripheral blood mononuclear cells (PBMCs) is regulated by PACMA-31 through transcriptional and posttranscriptional mechanisms

    L. Beckmann1, J. Mäder2, M. Voigtländer3, F. Klingler3, A. Schulenkorf3, C. Lehr3, C. Bokemeyer3, W. Ruf4, C. Rolling3, F. Langer3

  • Abstract Number: PB0457

    Title: Retrospective study of COVID patients diagnosed with VTE

    B. Packham

  • Abstract Number: PB0278

    To Load or not to Load: Safety and Efficacy of Warfarin Dosing in Pediatric Cardiology Patients

    J. Branstetter1, H. Zaki1, G. Woods2, M. Allard3

  • Abstract Number: PB0650

    To predict the impact of low dose prophylaxis vs. on demand treatment in severe Hemophilia A patients in Pakistan

    M. Borhany1, M. Abid1, R. Ahmed2, A. Jamal2, S. Zafar1, T. Shamsi3

  • Abstract Number: OC 72.5

    Toll-Like Receptor 4-Dependent and Independent platelet-dependent thrombosis in SARS-CoV-2 Infection

    V. Cammisotto1, R. Carnevale2, S. Bartimoccia2, C. Nocella2, M. Bufano2, V. Castellani2, L. Loffredo2, S. Sciarretta2, A. Coluccia2, R. Silvestri2, G. Ceccarelli2, A. Oliva2, M. Venditti2, F. Pugliese2, C. Mastroianni1, O. Turriziani2, P. Pignatelli3, F. Violi4

  • Abstract Number: PB0476

    Total Thrombus Formation Analysis System (T-TAS) Detects Poor Clot Formation in a Swine Model of Polytrauma and Hemorrhagic Shock

    A. Cralley1, E. Moore2, M. DeBot3, T. Schaid4, C. Fox5, A. Ghasabyan4, S. Mitra6, P. Hom4, K. Hansen1, M. Cohen1, C. Silliman1, A. Sauaia1

  • Abstract Number: OC 47.3

    Towards Explaining the Unique Bleeding Pattern of Acquired Hemophilia A: Impact of FVIII-containing Immune Complexes on Hemostasis

    O. Oleshko1, A. Klingberg2, U. Curth3, S. Werwitzke2, A. Tiede1

  • Abstract Number: OC 72.4

    Toxicity of neutrophil extracellular traps (NETs) and the effects of platelet factor 4 (PF4) on NET thrombogenicity: Therapeutic implications

    A. Ngo1, C. Field2, A. Sarkar1, I. Yarovoi1, G. Zhao1, L. Rauova1, M. Kowalska1, M. Poncz1, K. Gollomp1

  • Abstract Number: VPB1045

    Transcriptome-wide Association Studies reveal novel genes regulating plasma levels of hemostatic factors

    N. Le1, J. Huffman2, A. Morrison3, N. Smith4, P. De Vries3, M. Sabater-Lleal5

  • Abstract Number: OC 45.4

    Transcriptomic Analysis Of Plasma And Thrombus Extracellular Vesicles (Evs) For The Molecular Diagnosis Of Ischemic Stroke Etiology

    F. Machado1, J. Marta-Enguita1, C. Roncal2, J. Rodriguez2, J. Páramo3, R. Bermejo4, R. Muñoz5, J. Orbe6

  • Abstract Number: OC 12.1

    Transgene expression patterns after AAV8 delivery using hepatocyte promoter elements reveal expression in both hepatocytes and liver sinusoidal endothelial cells (LSECs)

    J. Lindgren1, D. Sabatino1, G. Nguyen1, A. Follenzi2, A. Henriksen1, R. Fama1

  • Abstract Number: PB0652

    Transition readiness among Dutch adolescents and young adults with haemophilia: a questionnaire study

    M. Brands1, E. Janssen2, C. Smit3, L. van Vulpen4, J. Eikenboom5, E. Beckers6, L. Hooimeijer7, M. Coppens8, S. Schols9, F. Leebeek10, M. Driessens11, F. Rosendaal12, M. Cnossen13, P. Van der Valk14, B. Laros15, J. van der Bom16, K. Fijnvandraat17, S. Gouw18

  • Abstract Number: PB1371

    Translation and Validation of the Caprini Risk Assessment Score for Urdu Speakers

    K. Lalani1, J. Bishop-Royse2, J. Tariman2, A. Tafur3

  • Abstract Number: OC 37.1

    Transplacental delivery of recombinant Fc-fused factor VIII (rFVIIIFc) in FVIII-deficient mice.

    A. Reyes Ruiz1, S. Lacroix-Desmazes2, S. Delignat1, A. Mimoun3, V. Daventure1, J. Dimitrov1

  • Abstract Number: OC 50.1

    Transplantation of fetal liver and adult bone marrow cells for phenotypic correction of hemophilia A.

    S. Akula1, S. merlin2, A. Cottonaro1, A. Follenzi3, M. sanchez4, e. borroni2, v. Kalandadze2, T. garcia leal4, L. Serrano ramos5, a. liras5, s. buzzi1

  • Abstract Number: PB0864

    TRAP-Induced platelet reactivity is inhibited by omega-3 fatty acid-derived prostaglandin E3 (PGE3).

    J. Osete-Lobato1, F. García2, N. Marín1, J. García-Estañ1, D. Iyu1

  • Abstract Number: PB1274

    Trauma Induces Intravascular Hemolysis, which is Associated with Adverse Clinical Outcomes: Potential Role of Released Arginase-1, Depletion of L-arginine, and Reduced Production of Nitric Oxide

    T. Schaid1, A. D'Alessandro2, E. Moore3, C. Silliman4, A. Sauaia4, M. DeBot5, C. Erickson4, I. Lacroix4, A. Cralley4, A. Banerjee6, K. Jones6, A. Ghasabyan7, S. Mitra6, M. Cohen4, K. Hansen4

  • Abstract Number: VPB0313

    Treatment and prognosis of children with inherited TTP: a single-center retrospective clinical study

    l. fu1, J. Ma2, R. Wu3, y. wei4

  • Abstract Number: PB0340

    Treatment by Line in Patients With Persistent and Chronic Immune Thrombocytopenia, A Real-World Point-In-Time Study

    M. Cooney1, S. Chang2, M. Isaila3, I. Leunikava4, J. DeCourcy5, K. Lewis5, S. Libby5, S. Zalpuri6

  • Abstract Number: PO0003

    Treatment challenge of an intracranial hemorrhage: a life-threatening complication of aplastic anemia

    C. Câmara1, M. Deveza1, C. Peixoto2, F. Pires1, M. Galvão3, Á. Beleza3

  • Abstract Number: OC 30.3

    Treatment Experience in Hemophilia Patients With and Without Inhibitors on Concizumab Prophylaxis: Hemo-TEM results from the phase 2 explorer4 & 5 studies

    M. Mancuso1, J. Skov Neergaard2, K. Cepo2, T. Porstmann3

  • Abstract Number: OC 21.3

    Treatment of Canine Hemophilia A via Intraosseous Delivery of a Platelet-Specific Factor VIII-Lentiviral Vector

    C. Rementer1, C. Li1, T. Nichols2, X. Cai1, J. Joo1, X. Wang1, E. Merricks3, H. Ochs1, D. Rawlings1, C. Miao1

  • Abstract Number: PB0754

    Treatment of hepatocellular carcinoma with autologous platelets encapsulating sorafenib or lenvatinib: a novel therapy exploiting tumor-platelet interactions

    H. Tanaka1, K. Horioka2

  • Abstract Number: PB0938

    Treatment of Splanchnic Vein Thrombosis with Anticoagulant Therapy in Cancer Patients: A Systematic Review and Meta-analysis

    A. Zahrai1, M. Carrier2, A. Delluc3

  • Abstract Number: PB1025

    Treatment with Peptide KRRKPGP and Warfarin Changes Anticoagulant Effects and Fibrinolysis in Metabolic Syndrome

    T. Obergan, T. Shubina, L. Lyapina, M. Grigorjeva

  • Abstract Number: VPB0757

    TREGs-induced Immune Thrombotic Thrombocytopenia in Polycythemia Vera

    R. Cacciola1, V. Vecchio2, E. Gentilini Cacciola3, E. Cacciola1

  • Abstract Number: PB0442

    Two Stage Intravital Imaging Mouse Model to Assess Venous Thromboembolism in Sickle Cell Disease

    T. Brzoska, T. Kaminski, P. Sundd

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