ISTH 2020 Congress

Coagulation and Natural Anticoagulants » Animal Models in Thrombosis and Hemostasis

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ISTH 2020 Congress
- Coagulation and Natural Anticoagulants
  - Animal Models in Thrombosis and Hemostasis

Abstract Number: OC 05.2

A Novel Contact Pathway Inhibitor Improves Hemostasis and Maintains Circuit Patency in a Piglet Model of Pediatric ECMO

C. Reed¹, D. Bonadonna², G. McDaniel³, J. Otto¹, J. Frederiksen¹, C. Chabata^1,4, B. Sullenger¹, E. Tracy¹

Abstract Number: PB0124

Anti-Aggregant Effect of Butanolic Extract of Rubia Tinctorum on Platelets in vitro and ex vivo

F.Z. Marhoume¹, Y. Zaid², A. Alioua³, A. Chait⁴, A. Bagri¹

Abstract Number: PB0144

Antithrombotic Properties of Carvedilol Shown in Two Independent Intravital Real Time Models of Thrombosis

P. Czajkowski¹, D. Jarmoc², T. Rusak², K. Kramkowski²

Abstract Number: PB0137

Cardiac Myosin Promotes Thrombin Generation and Coagulation in vitro and in vivo

M. Shukla¹, H. Deguchi¹, J. Zilberman-Rudenko^1,2, Y. Oyama³, T. Eckle³, Z. Guo¹, S. Lear¹, W. Shen¹, T. Wyseure¹, L. Mosnier¹, J. Orje¹, Z. Ruggeri¹, O. McCarty², J. Griffin¹

Abstract Number: PB0141

CRISPR/Cas9-Mediated Generation of a RUNX1 Knock-In Mice Model and Platelet Characterization

A. Marín-Quílez¹, R. Benito¹, I. García-Tuñón¹, C. Fernández-Infante¹, L. Hernández-Cano¹, A. Vega-Marín¹, L. Méndez-Sánchez², M. del Rey¹, J.L. Ordoñez¹, V. Palma-Barqueros³, M.L. Lozano³, M. Sánchez-Martín^1,2, C. Guerrero¹, J.R. González Porras⁴, J. Rivera³, J.M. Hernández-Rivas^1,4, J.M. Bastida⁴

Abstract Number: PB0122

Developing of a New Animal Artery Model of Atherothrombotic Stenosis using Perivascular Monopolar High-Frequency Electrical Current-Mediated Endothelial Injury Followed by a Cholesterol-Rich Diet Injury and Finally Perivascular Severe Cold Injury using Liquid Nitrogen

H. Mehrad¹, M. Farhoudi²

Abstract Number: PB0152

Early Indicators of Thromboembolic Events Caused by Prolonged Tourniquet Application: A Rat Model

J. Chung^1,2, O. Mian^2,3, A. Chan^2,4, D. Matino^2,4

Abstract Number: PB0150

Effects of Hibernation on the Platelet Proteome of 13-lined Ground Squirrels

S. Cooper¹, J. Cunliffe², P. Wilmarth², L. David², J. Aslan²

Abstract Number: PB0135

Fibrin Deposits on Peritoneal Carcinomatosis Serves as a Niche for Cancer Cell Implantation and Dissemination. A Scanning Electron Microscopy Analysis

I. Aldybiat¹, S. Mirshahi^1,2, R. Kaci¹, C. Pimpie¹, M. Pocard¹, J. Soria¹, M. Mirshahi¹

Abstract Number: PB0131

Heart Failure, Induced by Excess Neurohormonal Activation, Results in Significant but Non-Critical Telomere Shortening in Cardiomyocytes and Peripheral Blood Mononuclear Cells

H. Dörschmann^1,2, M. Brandt^1,2,3, V. Garlapati^1,2, T. Münzel^2,3, P. Wenzel^1,2,3

Abstract Number: PB0127

Hemolysis Triggers Platelet-Dependent Pulmonary Arteriole Thrombosis

T. Brzoska¹, R. Vats^1,2, M.F. Bennewitz^1,3, E. Tutuncuoglu¹, S.C. Watkins⁴, M.V. Ragni⁵, M.D. Neal⁶, M.T. Gladwin^1,7, P. Sundd^1,2,7

Abstract Number: PB0133

High Salt Intake Increases Platelet Counts and Plasma Fibrinogen Levels but Has No Effect on Thrombus Formation or Resolution in a Murine Model of Venous Thrombosis

J. Wild^1,2, T. Knopp¹, M. Molitor^1,2, L. Hobohm^1,2, T. Münzel², P. Wenzel^1,2, S. Karbach^1,2

Abstract Number: PB0151

Maternal Deficiency of Endothelial Protein C Receptor Causes Severe Pregnancy Complications Prevented by Inactivation of Protease Activated Receptor 4, but not Clotting Factor VIII

M. Castillo, A. Solis Sigala, J. Jarzembowski, R. Sood

Abstract Number: PB0139

Multiple Gene Knockdowns Simultaneously to Study Hemostasis in Zebrafish

R. Raman, M. Ryon, P. Jagadeeswaran

Abstract Number: OC 05.3

Neutrophil Extracellular Traps and Inflammasomes Form an Inflammatory Circuit Promoting Venous Thrombosis

J. Campos¹, T. Ponomaryov¹, A. De Prendegast¹, A. Brill^1,2

Abstract Number: PB0130

Non-Invasive Optical in vivo Imaging Reveals Tumor-Derived Prothrombin with a Functional Role in Hemostasis and Tumor Progression

L.K. Schott^1,2,3, L. Pruschinski^1,2,3, S. Khokar^1,2,3, L. Eder^1,2,3, K. Muhammad^1,2,3, S. Tokalov^1,2,3, J. Satrapa^1,2,3, M. Klein⁴, K. Lackner³, S. Danckwardt^1,2,3

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