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ISTH 2020 Congress

Coagulation and Natural Anticoagulants » Animal Models in Thrombosis and Hemostasis

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  • ISTH 2020 Congress
    • Coagulation and Natural Anticoagulants
      • Animal Models in Thrombosis and Hemostasis

Abstract Number: OC 05.2

A Novel Contact Pathway Inhibitor Improves Hemostasis and Maintains Circuit Patency in a Piglet Model of Pediatric ECMO

C. Reed1, D. Bonadonna2, G. McDaniel3, J. Otto1, J. Frederiksen1, C. Chabata1,4, B. Sullenger1, E. Tracy1

Abstract Number: PB0124

Anti-Aggregant Effect of Butanolic Extract of Rubia Tinctorum on Platelets in vitro and ex vivo

F.Z. Marhoume1, Y. Zaid2, A. Alioua3, A. Chait4, A. Bagri1

Abstract Number: PB0144

Antithrombotic Properties of Carvedilol Shown in Two Independent Intravital Real Time Models of Thrombosis

P. Czajkowski1, D. Jarmoc2, T. Rusak2, K. Kramkowski2

Abstract Number: PB0137

Cardiac Myosin Promotes Thrombin Generation and Coagulation in vitro and in vivo

M. Shukla1, H. Deguchi1, J. Zilberman-Rudenko1,2, Y. Oyama3, T. Eckle3, Z. Guo1, S. Lear1, W. Shen1, T. Wyseure1, L. Mosnier1, J. Orje1, Z. Ruggeri1, O. McCarty2, J. Griffin1

Abstract Number: PB0141

CRISPR/Cas9-Mediated Generation of a RUNX1 Knock-In Mice Model and Platelet Characterization

A. Marín-Quílez1, R. Benito1, I. García-Tuñón1, C. Fernández-Infante1, L. Hernández-Cano1, A. Vega-Marín1, L. Méndez-Sánchez2, M. del Rey1, J.L. Ordoñez1, V. Palma-Barqueros3, M.L. Lozano3, M. Sánchez-Martín1,2, C. Guerrero1, J.R. González Porras4, J. Rivera3, J.M. Hernández-Rivas1,4, J.M. Bastida4

Abstract Number: PB0122

Developing of a New Animal Artery Model of Atherothrombotic Stenosis using Perivascular Monopolar High-Frequency Electrical Current-Mediated Endothelial Injury Followed by a Cholesterol-Rich Diet Injury and Finally Perivascular Severe Cold Injury using Liquid Nitrogen

H. Mehrad1, M. Farhoudi2

Abstract Number: PB0152

Early Indicators of Thromboembolic Events Caused by Prolonged Tourniquet Application: A Rat Model

J. Chung1,2, O. Mian2,3, A. Chan2,4, D. Matino2,4

Abstract Number: PB0150

Effects of Hibernation on the Platelet Proteome of 13-lined Ground Squirrels

S. Cooper1, J. Cunliffe2, P. Wilmarth2, L. David2, J. Aslan2

Abstract Number: PB0135

Fibrin Deposits on Peritoneal Carcinomatosis Serves as a Niche for Cancer Cell Implantation and Dissemination. A Scanning Electron Microscopy Analysis

I. Aldybiat1, S. Mirshahi1,2, R. Kaci1, C. Pimpie1, M. Pocard1, J. Soria1, M. Mirshahi1

Abstract Number: PB0131

Heart Failure, Induced by Excess Neurohormonal Activation, Results in Significant but Non-Critical Telomere Shortening in Cardiomyocytes and Peripheral Blood Mononuclear Cells

H. Dörschmann1,2, M. Brandt1,2,3, V. Garlapati1,2, T. Münzel2,3, P. Wenzel1,2,3

Abstract Number: PB0127

Hemolysis Triggers Platelet-Dependent Pulmonary Arteriole Thrombosis

T. Brzoska1, R. Vats1,2, M.F. Bennewitz1,3, E. Tutuncuoglu1, S.C. Watkins4, M.V. Ragni5, M.D. Neal6, M.T. Gladwin1,7, P. Sundd1,2,7

Abstract Number: PB0133

High Salt Intake Increases Platelet Counts and Plasma Fibrinogen Levels but Has No Effect on Thrombus Formation or Resolution in a Murine Model of Venous Thrombosis

J. Wild1,2, T. Knopp1, M. Molitor1,2, L. Hobohm1,2, T. Münzel2, P. Wenzel1,2, S. Karbach1,2

Abstract Number: PB0151

Identification of Thrombosis Predictors in an ex vivo Shunt Model through Retrospective Analysis

M.W. Hagen1, H.H.S. Lakshmanan2, M.E. Fallon2, O.J.T. McCarty2, M.T. Hinds2

Abstract Number: PB0143

Immunization with Recombinant Atherogenic Antigen (AHC) Does Not Increase Susceptibility to Venous Thrombosis

M. Xia1, V. Endresz2, I. Lantos2, A. Szabo3, X. Lu1

Abstract Number: PB0128

Increased Levels of von Willebrand Factor Associated with Acute Inflammation Contribute to Enhanced Venous Thrombosis

S.J. Choi1, L. Swystun1, C. Hindmarch2, C. Dwyer1, A. Michels1, W. Hopman3, D. Lillicrap1

Abstract Number: PB0123

Liquorice and Sumac Attenuate Brain Damage Caused by Ischemic Stroke in Rat

A. Parsa1, R. Majidian2, S. Abasi1, F. Modjtahedi3, M. Babaeian1

Abstract Number: PB0142

Maternal Deficiency of Endothelial Protein C Receptor Causes Severe Pregnancy Complications Prevented by Inactivation of Protease Activated Receptor 4, but not Clotting Factor VIII

M. Castillo, A. Solis Sigala, J. Jarzembowski, R. Sood

Abstract Number: PB0139

Multiple Gene Knockdowns Simultaneously to Study Hemostasis in Zebrafish

R. Raman, M. Ryon, P. Jagadeeswaran

Abstract Number: OC 05.3

Neutrophil Extracellular Traps and Inflammasomes Form an Inflammatory Circuit Promoting Venous Thrombosis

J. Campos1, T. Ponomaryov1, A. De Prendegast1, A. Brill1,2

Abstract Number: PB0130

Non-Invasive Optical in vivo Imaging Reveals Tumor-Derived Prothrombin with a Functional Role in Hemostasis and Tumor Progression

L.K. Schott1,2,3, L. Pruschinski1,2,3, S. Khokar1,2,3, L. Eder1,2,3, K. Muhammad1,2,3, S. Tokalov1,2,3, J. Satrapa1,2,3, M. Klein4, K. Lackner3, S. Danckwardt1,2,3

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