Coagulation and Natural Anticoagulants

Abstract Number: OC 44.3

A new mouse model of impaired fibrin α-chain crosslinking shows increased venous thrombembolism

C. Duval¹, T. Feller², H. mcPherson¹, R. Ariëns³

Abstract Number: OC 65.3

A Phase 2 Trial Evaluating the Safety and Antithrombotic Efficacy of AB002, a First-in-class Protein C Activator in End-stage Renal Disease Patients on Heparin-free Hemodialysis

N. Verbout¹, C. Lorentz¹, B. Markway¹, M. Wallisch¹, J. Shatzel², E. Tucker¹

Abstract Number: PB0552

A Probable Therapeutic for a Child with Inherited Protein S Deficiency

V. Pereira¹, L. Thangada², M. khosla³, r. majumder⁴

Abstract Number: VPB0572

A study of the stability of fibrinogen and FXIII levels and microbial integrity of pooled cyroprecipitate stored at 1-6°C and 20-24°C for up to 120 hours

H. Kaur¹, A. Ang¹, S. Chua¹, P. Shu¹, C. Tan², W. Wong²

Abstract Number: OC 36.4

A Tethered Artificial Protease Reveals the Location of Key Regulatory Motifs in Factor V

F. Ayombil¹, R. Toso¹, R. Camire²

Abstract Number: PB0548

Abelacimab, a Factor XI/XIa Antibody Inhibits Clotting in Hemodialysis Circuits Ex Vivo

K. Kovacevic¹, C. Schörgenhofer², G. Langer², Y. Khder³, B. Jilma², J. Grafeneder⁴

Abstract Number: OC 44.1

Activation of the Plasma Contact System Triggers the Fat Embolism Syndrome

S. Konrath¹, S. Hemkemeyer¹, R. Mailer¹, K. Püschel¹, B. Ondruschka¹, T. Renné²

Abstract Number: OC 03.5

An Integrative Biology Approach to Model the Role of the Feedback Activation of FXI by Thrombin in the Tissue Factor Pathway

H. Lakshmanan¹, A. Estonilo², S. Reitsma³, A. Melrose³, T. Zheng³, J. Maddala⁴, D. Gailani⁵, P. Jurney², C. Puy³, O. McCarty⁶

Abstract Number: OC 36.3

Analysis of TFPI-protein S anticoagulant function in vivo.

A. Petri¹, P. Sasikumar¹, P. Badia Folgado¹, D. Jones², J. Ahnström¹, I. Salles-Crawley³, J. Crawley¹

Abstract Number: OC 65.2

Andexanet alfa is associated with a significant reduction in in-hospital mortality compared to 4F-PCC in a real-world analysis

P. Dobesh¹, C. Coleman², J. Ulloa³, B. Lovelace⁴, T. Dettling⁴, B. Koch⁴, G. Fermann⁵

Abstract Number: LB 01.5

Antiplatelet effects of inhibiting coagulation factor XI in a non-human primate model of atherosclerosis

H. Vu¹, T. Kohs¹, J. Pang¹, K. Jordan¹, T. Zheng¹, P. Kievit², J. Johnson¹, M. Wallisch³, M. Hinds¹, C. Puy¹, C. Lorentz³, E. Tucker⁴, D. Gailani⁵, J. Aslan¹, J. Shatzel¹, O. McCarty⁶, I. Parra-Izquierdo¹

Abstract Number: OC 67.1

Antithrombin deficiency and altered heparin responsiveness during veno-arterial extracorporeal life support: a prospective study

A. Mansour¹, M. Berahou², J. Odot², A. Pontis³, F. NEDELEC-GAC⁴, A. Parasido⁵, F. Reizine⁶, Y. Launey², A. Ousmen⁷, R. Garlantezec⁷, E. Flecher⁵, N. Nesseler⁸, I. Gouin⁹

Abstract Number: PB0547

Antithrombin deficiency is associated with more compact plasma fibrin clot structure and impaired susceptibility to fibrinolysis

A. Klajmon¹, M. Kopytek², J. Natorska³, A. Undas¹, M. Ząbczyk³

Abstract Number: PB1016

Argatroban Monitoring in Critically Ill Patients and correlation with Thrombin Generation

G. Scheriau¹, C. Schkömmer¹, L. Wagner², N. Binder², B. Steinlechner³

Abstract Number: VPB1019

Assessing the reversal efficacy of prothrombin complex concentrate (PCC) and andexanet alfa in rivaroxaban-anticoagulated blood: Ex vivo study

F. Rayatdoost¹, K. Deventer¹, H. Schöchl², O. Grottke¹

Abstract Number: VPB0570

Assessment of Impact of Metabolites of Edoxaban and Dabigatran on Fibrin and Thrombin Generation Assays

J. Evrard¹, R. Siriez¹, V. Maloteau¹, J. Dogné², J. Douxfils³

Abstract Number: PB1015

Assessment of Quantra Analyzer on life-threating bleeding under oral anticoagulants agents: a pilot study

D. Teissandier¹, C. Lucchini², J. Bouillon-Minois³, J. Schmidt⁴, T. Sinegre⁵, c. Morand⁶, A. Lebreton⁷, F. Moustafa⁴

Abstract Number: PB0542

Bio-equivalence of Potency adjusted approved heparin solutions compared to a newly developed heparin solution.

E. Krupa¹, D. Hoppensteadt², W. Jeske¹, A. Farooqui¹, A. Kouta¹, O. Iqbal¹, B. Kantarcioglu³, R. Krämer⁴, J. Fareed²

Abstract Number: PB1050

Blockade of K-ras signalling prevents coagulatory phenotype of alternatively activated macrophages.

P. Haider¹, J. Kral-Pointner², M. Salzmann², B. Podesser³, J. Wojta², P. Hohensinner³

Abstract Number: OC 03.3

Bradykinin Liberation from High Molecular Weight Kininogen by Plasma Kallikrein on Endothelial Cell Membranes is Modulated by Ambient Concentration of C1 inhibitor and Prolylcarboxypeptidase

A. Merkulova¹, S. Abdalian², G. Forbes³, P. Zeng³, A. Pinheiro³, A. Schmaier⁴