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ISTH 2021 Congress

Coagulation and Natural Anticoagulants » Coagulation Factors and Inhibitors

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    • Coagulation and Natural Anticoagulants
      • Coagulation Factors and Inhibitors

Abstract Number: PB0057

Ex vivo Evaluation of the Effect of Plasma-derived Factor VIII/von Willebrand Factor in Patients with Severe Hemophilia A on Prophylaxis with Emicizumab by ROTEM

E. Monzón Manzano1, E. Arias-Salgado1, P. Acuña1, M.-I. Bravo2, A. Raventos2, A. Perez2, M.T. Álvarez Román1, N. Butta1, M. Costa2, T. Willis3, V. Jimenez-Yuste1,4

Abstract Number: OC 05.3

A Novel Prediction Platform to Enhance the Design of Therapeutic SERPINs

W. Sanrattana1, T. Sefiane2, S. Smits1, M. Fens3, D. Monroe4, P. Lenting2, C. Maas1, S. de Maat1

Abstract Number: OC 27.4

A Unique Loop Structure in the A2-domain of Pseudonaja textilis Factor Va Prevents Activated Protein C-catalyzed A2-domain Dissociation

M. Schreuder1,2, X. Liu3, K.L. Cheung1, P.H. Reitsma1,4, G.A.F. Nicolaes3, M.H.A. Bos1

Abstract Number: LB 01.2

Abelacimab for Prevention of Venous Thromboembolism

P. Verhamme1, A. Yi2, A. Segers3, J. Salter2, D. Bloomfield2, H. Buller4, G. Raskob5, J. Weitz6

Abstract Number: PB0072

Analysis of Coagulation Factors in Fresh-frozen Plasma

M. Pikta1,2, T. Szanto3, R. Reimal4, P. Muliin4, H. König5, G. Blinova5, V. Banys6

Abstract Number: PB0058

Are Direct Oral Anti-Xa Inhibitors Absorbed in Cancer Patients after Gastrectomy? A Case Series

H.C. Puhr1, A. Ilhan-Mutlu1, P. Quehenberger1, P.A. Kyrle1, S. Eichinger1, L. Eischer1

Abstract Number: PB0051

Combining Heparin with a FX/FXa Aptamer to Reduce Thrombin Generation in Models of Cardiopulmonary Bypass and COVID-19 Associated Coagulopathy

C.V. Chabata1,2, J.W. Frederiksen1, L.B. Olson2,3, I.A. Naqvi4, B.A. Sullenger1

Abstract Number: PB0047

Comparing the Real-world and Clinical Trial Bleeding Rates Associated with Anticoagulation Treatment for Atrial Fibrillation

R. Buderi1, A. Yi2, P. Allen1, T. Bebi1, C. Vigna1, R. Jain1, A. Majumdar1, D. Bloomfield2, J. Salter2, D. Freedholm2, A. Galaznik1

Abstract Number: PB0045

D-dimer and the Risk of Diabetes: The REasons for Geographic and Racial Differences in Stroke (REGARDS)

D. Kamin Mukaz1, D.L. Long2, T.B. Plante1, S.E. Judd2, L.A. McClure3, A.S. Wolberg4, A.P. Carson2, B. Guo2, M. Cushman1

Abstract Number: OC 43.1

Deep Mutational Scan of the VWF C Domains to Define Mutations Associated with VWD

T. Sparring1, K. Singh1, H. Madarati1, C. Kretz1

Abstract Number: OC 14.3

Development of Monoclonal Antibodies that Protect FV/FVa from APC-mediated Inactivation for the Treatment of Bleeding

S. Quinn1, F. Ayombil1, R.M. Camire2

Abstract Number: OC 60.4

Discovery and in vitro Characterization of an Antibody Fragment (Fab) which Neutralizes Milvexian (BMS-986177/JNJ-70033093)

Y. Wu1, L. Schneeweis1, J. Pinckney2, C. Terragni2, S. Mai1, Y. An1, J. Gordon2, A. Kozhich1, A.K. Dilger1, W.R. Ewing1, P. Nandi1, J.M. Luettgen1

Abstract Number: PB0067

Evaluation and Performance Characteristics of the Automated Sysmex CN-6000 Haemostasis Analyzer

I. Martin-Toutain1, M. Gaaloul1, M. Berber1, E. Bailly1, J.-P. Delorme2, Y. Bourti2, C. Frere1,3

Abstract Number: PB0052

Evaluation of a New Thromboplastin Reagent Containing Human Recombinant Tissue Factor for the Determination of Prothrombin Time Reagent: the (h)PT-Phen™ LRT

I. Martin-Toutain1, M. Gaaloul1, J.-P. Delorme2, Y. Bourti2, C. Frere1,3

Abstract Number: OC 05.4

Evolutionary Adaptation of the Gamma-carboxyglutamic Acid Domain in Venom Factor X from the Australian Common Brown Snake

S. Cheng1,2, G. Poenou1,3, K.L. Cheung1, M. Schreuder1,4, M.H. Bos1

Abstract Number: PB0044

Factor XIa Inhibitor Milvexian (BMS-986177/JNJ-70033093) Suppresses Plasma Clot Formation and Reduces Resistance to Fibrinolysis in vitro

L.A. Holle1, J.M. Luettgen2, A.S. Wolberg1

Abstract Number: OC 05.2

Fluorescence Correlation Spectroscopy Provides New Insights into the Mechanism of Prothrombin Recognition by the Prothrombinase Complex

M. Chinnaraj1, N. Pozzi1, E. Di Cera1

Abstract Number: PB0038

Generation of Anticoagulant RNA Aptamers Targeting Cofactors that Inhibit Clotting in Normal and COVID-19 Patient Samples

H. Yu1, E. Soule1, L. Olson1, I. Naqvi1, S. Kumar2, S. Krishnaswamy2, B. Sullenger1

Abstract Number: PB0055

HemosIL Liquid Anti-Xa Apixaban Measurement in Patients with High Risk of Major Bleeding

J. Hammelburger1, Z. Cao1, C. Kung1

Abstract Number: PO121

Hemostatic Defects Associated with IgA Monoclonal Gammopathy

M.C. Shen1,2, C.-W. Huang1, G.-M. Lai1, Y.-H. Shih1, C.-Y.L. Lin1, H.-Y. Lin1, S.-F. Kuo1, J.-S. Lin1

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