Hemostatic Systems in Cancer, Inflammation and Immunity » Coagulation Proteins Beyond Hemostasis

Abstract Number: PB0726

(Factor VIII / Factor V) Ratio as a New Prognostic Marker for Decompensated Liver Cirrhosis

M. El Horri¹, N. Feghoul¹, F. El Horri², I. Khachaa¹, A. Chikh Khelifa³, M. Baghdadi¹, A. Benglia¹, K. Benbouhadi¹, H. Mimene¹, K. Kebir¹, K. Benhalima¹, L. Benmahdi¹, H. BROUK⁴

Abstract Number: PB0728

Bladder cancer patients have increased NETosis and impaired DNaseI-mediated NET degradation that can be therapeutically restored in vitro

R. Herranz¹, J. Oto¹, M. Hueso², E. Plana³, F. Cana², A. Fernández-Pardo², S. Bonanad⁴, C. Vera-Donoso⁵, M. Martínez-Sarmiento⁵, P. Medina²

Abstract Number: PB0730

Circulating activated protein C levels are reduced in cancer patients, a novel contribution to tumorigenesis?

J. Oto¹, R. Herranz¹, E. Plana², F. Cana³, J. Amaya⁴, C. Vera-Donoso⁵, M. Martínez-Sarmiento⁵, S. Bonanad⁶, P. Medina³

Abstract Number: OC 28.3

Coagulation factor XII induces persistent uPAR-integrin β1 signaling promoting DNA damage and senescence in diabetic kidneys

A. Elwakiel¹, K. Shahzad¹, I. Gadi¹, R. Rana¹, D. Gupta¹, J. Manoharan¹, S. Kohli¹, T. Renné², B. Isermann¹

Abstract Number: OC 28.5

Coagulation FXI regulates endothelial cell barrier function by inducing VE-cadherin proteolysis in an ADAM10-dependent manner

C. Puy¹, K. Jordan¹, N. Nguyen², C. Lorentz³, E. Tucker³, D. Gailani⁴, O. McCarty⁵

Abstract Number: PB0729

Development of a viral vector for hemopexin protein expression for gene therapy in disorders associated with increased levels of free extracellular heme

F. Lima¹, B. Hounkpe¹, C. Peachazepi de Moraes², I. Borba³, F. Costa¹, E. de Paula⁴

Abstract Number: OC 51.1

Direct oral anticoagulants cause placental vascular abnormalities and epigenetic reprogramming in placenta and the offspring

K. Singh¹, A. Gupta¹, R. Younis¹, H. Mai¹, K. Shahzad², B. Isermann², S. Kohli²

Abstract Number: OC 28.1

Factor X – Protease activated receptor-2 signaling in the regulation of diet-induced obesity

D. Kaur¹, M. Thati¹, W. Ruf²

Abstract Number: PB0732

Fibrin Promotes Glioblastoma Progression via Focal Adhesion Kinase

L. Knowles¹, C. Wolter², R. Ketter³, S. Urbschat³, S. Linsler³, S. Müller³, A. Müller⁴, X. Zhou⁵, B. Qu⁶, E. Hermann⁷, J. Pilch⁸

Abstract Number: PB0733

Frequency of Factor II, Factor V Leiden and MTHFR mutations in children with cancer

J. Roganovic

Abstract Number: OC 66.4

Increased Endothelial Secretion and Reduced Circulatory Clearance Contribute to Elevated Plasma von Willebrand Factor Levels in Multiple Myeloma

C. Comerford¹, S. Pal Singh Dhami², P. Murphy³, S. Patmore², S. Ward², U. Budde⁴, J. O'Donnell², S. Glavey³, J. Quinn³, J. O'Sullivan⁵

Abstract Number: PB0731

Neutrophil activation markers as novel biomarkers for advanced stages of high-grade serous ovarian cancer

J. Oto¹, B. Mc Cormack², S. Tomás-Pérez², A. Fernández-Pardo³, E. González-Cantó², F. Cana³, C. Aghababyan⁴, R. Herranz¹, S. Cañete-Mota⁵, A. Cuadros-Lozano⁴, L. Martínez-Fernández⁴, A. Aranda-Borreda², A. Arroyo-Álvarez², N. Santonja-López⁶, R. Ramírez-Belloch⁷, A. Llueca-Abella⁸, J. Marí-Alexandre J², J. Gilabert-Estellés⁹, P. Medina³

Abstract Number: VPB0737

Prevalence and Impact of Antiphospholipid Antibodies on Thrombotic Events in Ambulatory Cancer Patients

C. Kansuttiviwat¹, P. Niprapan², L. Norasetthada², E. Rattaritamrong², A. Tantiworawit², P. Piriyakhuntorn², S. Hantrakool³, N. Hantrakun², T. Punnachet², C. Chai-Adisaksopha²

Abstract Number: OC 28.4

Protective Role of Plasminogen Deficiency in Non-Alcoholic Fatty Liver Disease and Glucose Dysmetabolism

W. Hur, Y. Nguyen, K. King, Y. Patel, M. Flick

Abstract Number: VPB0736

Prothrombin can modulate its expression in colon cancer cells

M. Cumbo¹, S. Dunjic Manevski², B. Tomic², M. Gvozdenov², V. Djordjevic²

Abstract Number: PB0725

Role of von Willebrand factor Antigen as Non-invasive Biomarker for the Prediction of Portal Hypertensive Gastropathy in Patients with Liver Cirrhosis

M. El Horri¹, F. El Horri², A. Chikh Khelifa³, M. Chekkal⁴, K. Benbouhadi¹, H. Mimene¹, K. Kebir¹, K. Benhalima¹, A. Benglia¹, L. Benmahdi¹, H. BROUK⁵

Abstract Number: OC 66.1

The Factor XII-uPAR Axis Drives Ovarian Cancer Maintenance and Progression

K. Bane¹, A. Gandhi², J. McAnulty², D. Bohinc³, A. DiFeo², E. Stavrou⁴

Abstract Number: PB0727

The induction of Tregs by aPC depends on metabolic reprogramming and reduced αKG levels

D. Gupta¹, A. Elwakiel², S. Ranjan², M. Pandey², S. Krishnan³, R. Henschler⁴, S. Kohli¹, B. Isermann¹

Abstract Number: PB0735

Understanding fate of circulating von Willebrand factor following interaction with polymorphonuclear leukocytes

A. Kuanyshbek¹, H. Yadegari², J. Oldenburg³

Abstract Number: PB0734

Visualization of Gliomas with Clot-binding Peptides

C. Wolter¹, L. Knowles², S. Linsler³, S. Müller³, M. Jung⁴, E. Hermann⁵, J. Pilch⁶