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ISTH 2022 Congress

Coagulation and Natural Anticoagulants » FVIII/IX

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Abstract Number: OC 55.2

Characterization of the Factor VIII and LRP1 Interaction Suggests a Dynamic Binding Mode with Switching of Alternative Multiple Canonical Bivalent and Non-Canonical Electrostatic Contacts

H. Chun1, J. Kurasawa2, P. Olivares1, E. Marakasova1, S. Shestopal1, G. Hassink3, E. Karnaukhova1, M. Migliorini4, J. Obi5, A. Smith5, P. Wintrode5, P. Durai6, K. Park6, D. Deredge5, D. Strickland4, A. Sarafanov1

Abstract Number: OC 74.1

Substitution of the Factor IX Activation Sites for Characterization of the Factor IX Activation Pathway and Partially Activated Intermediates

J. Vatandoost1, S. Cheng2, K. Cheung3, N. Shifai4, M. Mayorga4, V. Strijbis5, M. Bos6

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