ISTH 2020 Congress

Hemophilia and Rare Bleeding Disorders » Hemophilia - Clinical

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ISTH 2020 Congress
- Hemophilia and Rare Bleeding Disorders
  - Hemophilia - Clinical

Abstract Number: PB0972

“Best of Both Worlds”: Combination Treatment of Desmopressin and FVIII Concentrates in Hemophilia Patients Optimizes Therapy and Reduces Costs

L.G.R. Romano¹, L.M. Schütte¹, R.M. van Hest², K. Meijer³, B.A.P. Laros-van Gorkom⁴, L. Nieuwenhuizen⁵, J. Eikenboom⁶, F.C.J.I. Moenen⁷, N. Uitslager⁸, M. Coppens⁹, M.H. Cnossen¹⁰, K. Fijnvandraat^11,12, M.H.E. Driessens¹³, S. Polinder¹⁴, F.W.G. Leebeek¹, R.A.A. Mahtôt², M.J.H.A. Kruip¹

Abstract Number: PB1058

Case report: Inhibitor Improvement with Low Dose Immune Tolerance Induction (ITI) with rFVIIIFc and Emicizumab after Failed First Line Therapy with High Dose ITI

I. Wieland¹, K.-A. Lambeck¹, D. Stichel², A. Orlowski², C. Königs²

Abstract Number: PB1041

3D Gait Analysis, Hemophilia Joint Health Score, Leg Muscle Laterality, and Biomarkers of Joint Damage: A Cross-sectional Comparative Assessment of Hemophilic Arthropathy

P. Putz¹, S. Durstberger², C. Kaufmann², M. Klinger², K. Widhalm², J. Rejtö³, C. Male⁴, I. Pabinger³

Abstract Number: PB0905

A Canadian, Multi-Center, Retrospective, Non-Interventional Study of Clinical Outcomes from Early Use of N9-GP Compared with Previous Treatment in Patients with Hemophilia B in a Real-World Setting

D. Matino¹, A. Iorio¹, A. Keepanasseril¹, F. Germini², A.C. Birkegård³, A. Caillaud⁴, M. Carcao⁵, J. Hews-Girard⁶, E. Iserman⁷, P. James⁸, A. Lee⁹, C. Phua¹⁰, H. Sun¹¹, J. Teitel¹², M.-C. Poon¹³

Abstract Number: PB1075

A Descriptive Study of Physical Activity and Fitness Level Profiles of Nigerians with Haemophila

H. Okoye¹, T. Nwagha¹, N. Chigbo², E. Anekwu³

Abstract Number: PB0889

A French Multicentre Prospective, Non-Interventional Study (B-SURE) Evaluating Real-World Usage and Effectiveness of Recombinant Factor IX Fc Fusion Protein (rFIXFc) in People with Haemophilia B: Baseline Data

H. Chambost¹, B. Wibaut², A. Borel Derlon³, S. Claeyssens⁴, S. Castet⁵, R. d'Oiron^6,7, C. Negrier⁸, H. Andersson⁹, S. Bergenstråle⁹, C. Gandossi¹⁰, C. Martinez¹⁰

Abstract Number: PB1034

A Multicenter Open-label Single Arm Trial to Evaluate Safety and Efficacy and Pharmacokinetics of Recombinant Human Coagulation Factor VIII (SCT800) in Previously Treated Patients with Severe Hemophilia A under Prophylaxis Therapy

W. Liu¹, X. Zhao², F. Xue¹, J. Sun³, X. Zeng⁴, F. Yang⁵, Z. Yu⁶, M. Xu⁷, W. Li⁸, W. Gu⁹, Y. Feng¹⁰, C. Zheng¹¹, H. Bi¹², R. Yang¹

Abstract Number: PB0896

A Randomized Controlled Trial: Pharmacokinetic-Guided Dosing of Factor VIII Concentrate Versus Standard Replacement Therapy in Perioperative Hemophilia A Patients (OPTI-CLOT Trial)

I. van Moort¹, T. Preijers², L. Bukkems², H. Hazendonk¹, B. Laros-van Gorkom³, E. Beckers⁴, L. Nieuwenhuizen⁵, F. van der Meer⁶, P. Ypma⁷, M. Coppens⁸, K. Fijnvandraat^9,10, R. Schutgens¹¹, K. Meijer¹², F. Leebeek¹³, R. Mathot², M. Cnossen¹, OPTI-CLOT Study Group

Abstract Number: PB0957

A Randomized, Multicenter, Open-label, Phase III Clinical Trial to Evaluate the Efficacy, Safety, and Pharmacokinetics of Prophylactic Emicizumab Versus No Prophylaxis in Persons with Hemophilia A in the Asia-Pacific region (HAVEN 5)

S. Wang¹, X. Zhao², X. Wang³, J. Sun⁴, A. Chuansumrit⁵, J. Zhou⁶, L. Li⁷, W. Hsu⁷, J. Xu⁷, P. Barrington⁸, R. Yang⁹

Abstract Number: PB0875

A Real-World Qualitative Analysis of the Burden of Hemophilia B and Patient Experiences with Prophylactic Nonacog Beta Pegol

C. Phua¹, M. Faurby², V. Macdonald³, J. Lambert⁴, J. Teitel⁵

Abstract Number: PB1053

A Simplified Health Education Program Improves Knowledge and Practices of Home Treatment in Hemophilia A Adolescents in a Developing Country

T. Hassan¹, M. Hesham¹, A. El Dakhakhny², M. Zakaria¹, M. Hanfy²

Abstract Number: PB0953

A Single Center Data on Extended Half-Life Recombinant Factor VIII (FVIII:Fc) in Patients with Hemophilia A

S. Braham¹, R. Gualtierotti², E. Biguzzi¹, S.M. Siboni¹, E. Bregani³, M. Boscarino⁴, M.E. Mancuso¹, F. Peyvandi^1,2

Abstract Number: PB1062

A Snapshot of a Prospective, Non-interventional Study to Evaluate Routine Practice Prophylactic Treatment Schedules – NIS-Previq

S. Halimeh¹, W. Behnisch², C. Escuriola-Ettingshausen³, J. Feddern⁴, A. Huth-Kühne⁵, J. Oldenburg⁶, U. Scholz⁷, S. Seeger⁴, S. Wenning⁵, R. Klamroth⁸

Abstract Number: PB0954

Abdominal Catastrophe in Hemophilic Patients: Towards Wise Decision Making

M. Abdelkader Morad, M. Elkholy, M. Mattar, M. Hasab Allah, A. Ayad, S. Habib, G. Nashed

Abstract Number: PB0962

Adverse Event Reporting in Haemophilia A Patients with and without Inhibitors Treated with Emicizumab: A Report from the Co-morbidity Working Party of the UK Haemophilia Centres Doctors´ Organisation (UKHCDO)

C. Wall¹, G. Hall², P. Collins³, M. Makris⁴, S. Shapiro⁵, R. Liesner⁶, C. Harrison⁴, R. Maclean⁴, S. Mangles⁷, G. Benson⁸, G. Evans⁹, P. Sartain¹⁰, C. Hay¹¹, UK National Haemophilia Database

Abstract Number: OC 09.3

An Insight into Clinical Outcomes in Mild, Moderate, and Severe Hemophilia A (HA): A Preliminary Analysis of the CHESS II Study

F. Nissen¹, T. Burke², S. Asghar², E. Ferri Grazzi², A. Shang¹, F. Castro¹, M. Aizenas¹, O. Meier¹, J. O'Hara^2,3

Abstract Number: PB1055

ASCVD Risk Score among Haemophilia Patients: Time to Formally Evaluate Cardiovascular Risk in People with Haemophilia

R. Camelo^1,2,3, B.P. Duarte², M.C.B. Moura², N.C.M. Costa², I.M. Costa², C.G.P. Roncal², A.M. Vanderlei², T.M.R. Guimaraes², C. Caram Deelder^3,4, S.C. Gouw³, S.M. Rezende¹, J.G. van der Bom^3,4

Abstract Number: PB0897

Assessing the Bleeding Phenotype in Non-Severe hemophilia by use of the ISTH Bleeding Assessment Tool (BAT)

F.R. Kloosterman¹, A. Zwagemaker¹, C.N. Bagot², E.A.M. Beckers³, J.G. van der Bom⁴, P. Collins⁵, M.H. Cnossen⁶, M. Coppens⁷, S.C. Gouw^1,4, B.A.P. Laros-van Gorkum⁸, S. Mangles⁹, F.J.M. van der Meer¹⁰, K. Meijer¹¹, L. Nieuwenhuizen¹², R. Schutgens¹³, K. Fijnvandraat¹

Abstract Number: PB1012

Association Between Aging and Health Status in Persons Leaving with Hemophilia and Controls Without a Bleeding Disorder – Insights from the PROBE Study

F. Germini^1,2, S. O'Callaghan³, C. Chai-Adisaksopha^2,4, R. Curtis⁵, N. Frick⁶, M. Nichol⁷, D. Noone^8,9, B. O'Mahony¹⁰, D. Page¹¹, J. Stonebraker¹², M. Skinner^1,13, A. Iorio^1,14, PROBE investigators

Abstract Number: PB1056

Association between Platelet Glycoprotein Common SNVs and Bleeding Severity in Haemophilia Patients

L. Bury¹, G. Piroli¹, H. Kuchi Bhotla¹, M. Borghi¹, E. Cesari¹, E. Falcinelli¹, R. De Cristofaro^2,3, B. Zieger⁴, P. Gresele¹

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