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ISTH 2020 Congress

Platelets and Megakaryocytes » Megakaryocytes and Thrombopoiesis

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    • Platelets and Megakaryocytes
      • Megakaryocytes and Thrombopoiesis

Abstract Number: PB1609

A Close Relationship between Adipocytes and Megakaryocytes

C. Valet, A. Batut, A. Vauclard, A. Dortignac, M. Bellio, B. Payrastre, P. Valet, S. Severin

Abstract Number: PB1599

A Novel Image-Based Chemical-Genetics Screen Identifies Inducers of Platelet Release from Immortalized Megakaryocytic Cell Lines, Enabling Clinical-Scale Production of Functional Platelets

A. Bhan1, N. Kareddy2, E. Forde2, G. Merrill-Skoloff3, B. Furie3, A. Frelinger2, G. Daley1, T. Schlaeger1

Abstract Number: PB1614

Accelerated Death of Wiskott-Aldrich Syndrome Megakaryocytes

S. Obydennyi1,2, O. Fedyanina1,2, S. Kuznetsova1,2, A. Khoreva2, F. Ataullakhanov1,2,3, A. Shcherbina2, M. Panteleev1,2,3

Abstract Number: PB1605

Autoantibody Mediated Changes in Megakaryocytes Glycan Pattern: Potential Impact on Thrombopoiesis in Immune Thrombocytopenia

I. Marini1, J. Zlamal1, L. Pelzl1, K. Althaus1,2, T. Bakchoul1,2

Abstract Number: PB1597

Combined α4a- and β1-Tubulin Deficiencies Profoundly Affect Platelet Biogenesis and Haemostasis

Q. Kimmerlin1, S. Moog1, A. Yakusheva1,2, A. Eckly1, C. Gachet1, P. Mangin1, C. Strassel1, F. Lanza1

Abstract Number: PB1602

Dysfunctional RBM8A/Y14 Does Not Impair Megakaryopoiesis but Terminal Thrombopoiesis in Thrombocytopenia Absent Radii (TAR) Syndrome

G. Manukjan1, C. Brähler1, M. Becker1, H. Bösing1, C.K. Kwok2, F. Edenhofer2, C. Ghevaert3, D. French4, H. Schulze1

Abstract Number: PB1603

Essential Thrombocythemia (ET): A Study of Clinical Features and Treatment Outcome in Pediatric Patients at King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

M. Ameen1, A. Almusa2, K. Sidiqui2, M. Alsaleh3, A. Aljefri3

Abstract Number: PB1608

Generation of Megakaryocytes from Human Bone Marrow Aspirates as a Simple Diagnostic and Research Tool: Assay Development and Validation

K. Butov1,2, N. Mikhalkin2, R. Nikolaev3, A. Volkova4, E. Osipova1, K. Machlus5, M. Panteleev1,2

Abstract Number: PB1616

Hyperactive SRC Kinase Results in Inherited Thrombocytopenia: Transcriptomics and Proteomics to Delineate the Defect in Megakaryopoiesis

L. De Kock, C. Thys, C. Van Geet, K. Freson

Abstract Number: PB1620

Ikaros/AhR Interaction Favors Expansion of Megakaryocytic Precursors with a High Potential to Produce Proplatelets

V. Do Sacramento1, L. Mallo1, S. Chan2, C. Gachet1, F. Lanza1, H. de la Salle1, C. Strassel1

Abstract Number: PB1615

Impact of Irradiation on the Bone Marrow Matrix and Megakaryopoiesis

K. Faber1, D. Semeniak1, K.G. Heinze2, H. Schulze1

Abstract Number: PB1606

Megakaryocyte Mitochondrial Dynamics and Oxidative Metabolism Are Essential to Initiate Platelet Biogenesis

S. Poirault-Chassac1, V. Nivet-antoine1,2, A. Houvert3, A. Kauskot4, E. Lauret3, R. Lai-Kuen5, I. Dusanter-Fourt3, D. Baruch1

Abstract Number: PB1596

Megakaryocytes Possess a Functional Necroptosis Pathway

D. Moujalled, P. Gangatirkar, J. Corbin, M. Kauppi, N. Lalaoui, J. Hildebrand, J. Silke, W. Alexander, E. Josefsson

Abstract Number: PB1601

Mesenchymal Stromal Cells Display Metabolic Alterations in JAK2-Mutant Myeloproliferative Neoplasms

T. Sun, A. Zhang

Abstract Number: PB1618

Rap1a/b Isoforms Differentially Regulate Megakaryocyte Biology

D. Ghalloussi1, G. Harousseau1, A. Eckly2, J.P. Kenny1, C. Kirkpatrick1, E.C. O'Shaughnessy3, K. Hahn3, C. Gachet2, L. Stefanini4, K. Eto5, W. Bergmeier1

Abstract Number: PB1617

Role of Platelet Production/Destruction Imbalance on the Interindividual Variability in Aspirin Response in Diabetic and Non-diabetic Patients

R. Liani1, P.G. Simeone1, R. Tripaldi1, A. Boccatonda2, D. D'Ardes2, M. Golato3, S. Ciotti1, M. Luongo3, V. Creato1, R. Pepe1, F. Santilli1

Abstract Number: PB1611

Short-term Application of Caffeic Acid Specifically Promotes Expansion of Hematopoietic Stem Cells

R. Wang, Y. Liu, X. Liu, Y. Liu, Y. Wang, M. Hou

Abstract Number: PB1598

Systmetic Study of Biological Properties and Functions of Bone Marrow Mesenchymal Stem Cells from Patients with Essential Thrombocythemia and Explore the Effects of Interferonα-2b on Them

T. Sun, A. Zhang

Abstract Number: PB1607

The Ablation of Collagen VI Leads to the Release of Platelets with Altered Functions

V. Abbonante1,2, C.A. Di Buduo1,2, M. Battiston3, M. Chrisam4, L. Sereni5, C. Semplicini6, A. Villa5,7, E. Pegoraro6, P. Braghetta4, L. De Marco3, P. Bonaldo4, A. Balduini1,2

Abstract Number: PB1610

Thrombopoiesis in Bone Marrow Culture in Norm and in Some Pathological States

T. Saralidze1, T. Svanidze1, I. Mamatsashvili1, N. Metskhvarishvili2, M. Rizhvadze3, M. Jangidze4, M. Noniashvili1

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