Platelets and Megakaryocytes » Megakaryocytes and Thrombopoiesis

Abstract Number: PB1609

A Close Relationship between Adipocytes and Megakaryocytes

C. Valet, A. Batut, A. Vauclard, A. Dortignac, M. Bellio, B. Payrastre, P. Valet, S. Severin

Abstract Number: PB1599

A Novel Image-Based Chemical-Genetics Screen Identifies Inducers of Platelet Release from Immortalized Megakaryocytic Cell Lines, Enabling Clinical-Scale Production of Functional Platelets

A. Bhan¹, N. Kareddy², E. Forde², G. Merrill-Skoloff³, B. Furie³, A. Frelinger², G. Daley¹, T. Schlaeger¹

Abstract Number: PB1614

Accelerated Death of Wiskott-Aldrich Syndrome Megakaryocytes

S. Obydennyi^1,2, O. Fedyanina^1,2, S. Kuznetsova^1,2, A. Khoreva², F. Ataullakhanov^1,2,3, A. Shcherbina², M. Panteleev^1,2,3

Abstract Number: PB1605

Autoantibody Mediated Changes in Megakaryocytes Glycan Pattern: Potential Impact on Thrombopoiesis in Immune Thrombocytopenia

I. Marini¹, J. Zlamal¹, L. Pelzl¹, K. Althaus^1,2, T. Bakchoul^1,2

Abstract Number: PB1597

Combined α4a- and β1-Tubulin Deficiencies Profoundly Affect Platelet Biogenesis and Haemostasis

Q. Kimmerlin¹, S. Moog¹, A. Yakusheva^1,2, A. Eckly¹, C. Gachet¹, P. Mangin¹, C. Strassel¹, F. Lanza¹

Abstract Number: PB1602

Dysfunctional RBM8A/Y14 Does Not Impair Megakaryopoiesis but Terminal Thrombopoiesis in Thrombocytopenia Absent Radii (TAR) Syndrome

G. Manukjan¹, C. Brähler¹, M. Becker¹, H. Bösing¹, C.K. Kwok², F. Edenhofer², C. Ghevaert³, D. French⁴, H. Schulze¹

Abstract Number: PB1603

Essential Thrombocythemia (ET): A Study of Clinical Features and Treatment Outcome in Pediatric Patients at King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

M. Ameen¹, A. Almusa², K. Sidiqui², M. Alsaleh³, A. Aljefri³

Abstract Number: PB1608

Generation of Megakaryocytes from Human Bone Marrow Aspirates as a Simple Diagnostic and Research Tool: Assay Development and Validation

K. Butov^1,2, N. Mikhalkin², R. Nikolaev³, A. Volkova⁴, E. Osipova¹, K. Machlus⁵, M. Panteleev^1,2

Abstract Number: PB1616

Hyperactive SRC Kinase Results in Inherited Thrombocytopenia: Transcriptomics and Proteomics to Delineate the Defect in Megakaryopoiesis

L. De Kock, C. Thys, C. Van Geet, K. Freson

Abstract Number: PB1620

Ikaros/AhR Interaction Favors Expansion of Megakaryocytic Precursors with a High Potential to Produce Proplatelets

V. Do Sacramento¹, L. Mallo¹, S. Chan², C. Gachet¹, F. Lanza¹, H. de la Salle¹, C. Strassel¹

Abstract Number: PB1615

Impact of Irradiation on the Bone Marrow Matrix and Megakaryopoiesis

K. Faber¹, D. Semeniak¹, K.G. Heinze², H. Schulze¹

Abstract Number: PB1606

Megakaryocyte Mitochondrial Dynamics and Oxidative Metabolism Are Essential to Initiate Platelet Biogenesis

S. Poirault-Chassac¹, V. Nivet-antoine^1,2, A. Houvert³, A. Kauskot⁴, E. Lauret³, R. Lai-Kuen⁵, I. Dusanter-Fourt³, D. Baruch¹

Abstract Number: PB1596

Megakaryocytes Possess a Functional Necroptosis Pathway

D. Moujalled, P. Gangatirkar, J. Corbin, M. Kauppi, N. Lalaoui, J. Hildebrand, J. Silke, W. Alexander, E. Josefsson

Abstract Number: PB1601

Mesenchymal Stromal Cells Display Metabolic Alterations in JAK2-Mutant Myeloproliferative Neoplasms

T. Sun, A. Zhang

Abstract Number: PB1618

Rap1a/b Isoforms Differentially Regulate Megakaryocyte Biology

D. Ghalloussi¹, G. Harousseau¹, A. Eckly², J.P. Kenny¹, C. Kirkpatrick¹, E.C. O'Shaughnessy³, K. Hahn³, C. Gachet², L. Stefanini⁴, K. Eto⁵, W. Bergmeier¹

Abstract Number: PB1617

Role of Platelet Production/Destruction Imbalance on the Interindividual Variability in Aspirin Response in Diabetic and Non-diabetic Patients

R. Liani¹, P.G. Simeone¹, R. Tripaldi¹, A. Boccatonda², D. D'Ardes², M. Golato³, S. Ciotti¹, M. Luongo³, V. Creato¹, R. Pepe¹, F. Santilli¹

Abstract Number: PB1611

Short-term Application of Caffeic Acid Specifically Promotes Expansion of Hematopoietic Stem Cells

R. Wang, Y. Liu, X. Liu, Y. Liu, Y. Wang, M. Hou

Abstract Number: PB1598

Systmetic Study of Biological Properties and Functions of Bone Marrow Mesenchymal Stem Cells from Patients with Essential Thrombocythemia and Explore the Effects of Interferonα-2b on Them

T. Sun, A. Zhang

Abstract Number: PB1607

The Ablation of Collagen VI Leads to the Release of Platelets with Altered Functions

V. Abbonante^1,2, C.A. Di Buduo^1,2, M. Battiston³, M. Chrisam⁴, L. Sereni⁵, C. Semplicini⁶, A. Villa^5,7, E. Pegoraro⁶, P. Braghetta⁴, L. De Marco³, P. Bonaldo⁴, A. Balduini^1,2

Abstract Number: PB1610

Thrombopoiesis in Bone Marrow Culture in Norm and in Some Pathological States

T. Saralidze¹, T. Svanidze¹, I. Mamatsashvili¹, N. Metskhvarishvili², M. Rizhvadze³, M. Jangidze⁴, M. Noniashvili¹