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ISTH 2021 Congress

Platelets and Megakaryocytes » Platelet Signaling

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  • ISTH 2021 Congress
    • Platelets and Megakaryocytes
      • Platelet Signaling

Abstract Number: PB1025

A rRle for the JAK/STAT5 Axis in GPVI-mediated Platelet Function

I. Parra Izquierdo1, A. R. Melrose1, J. Pang1, S.H. Vasilipalli1, S. E. Reistma1, H.H. Sudhan Lakshmanan1, M. K. Larson2, O. J.T. McCarty1, J. E. Aslan1

Abstract Number: PB1026

Acetyl-CoA Carboxylase Inhibition Alters Tubulin Acetylation and Aggregation in Thrombin-stimulated Platelets

M. Octave1, L. Pirotton1, A. Ginion1, V. Robaux1, S. Lepropre1, S. Kautbally1, V. Darley-Usmar2, J. Ambroise3, B. Guigas4, M. Giera4, M. Foretz5, L. Bertrand1, C. Beauloye1, S. Horman1

Abstract Number: PB1029

Annexin V Binding Detects Platelet Procoagulant Commitment but Is Not Sensitive to Reductions in the Level of Platelet PS Exposure

S. Millington-Burgess1, M. Harper1

Abstract Number: PB1033

Antiplatelet Effect of Nobiletin Is Mediated by Activation of DP1 Receptor

V. Shpakova1, A. Avdeeva2, S. Gambaryan1, N. Rukoyatkina1

Abstract Number: LPB0132

Chronic Edible Dosing of Δ9-tetrahydrocannabinol (THC) in Non-human Primates Reduces Systemic Platelet Activity and Function

S.E. Reitsma1, J. Johnson1, J. Pang1, I. Parra-Izquierdo1,2, H. Hara Sudhan Lakshmanan1, A.R. Melrose2,1, M. T. Hinds1, J.E. Aslan2,1, O.J. McCarty1, J.O. Lo3

Abstract Number: PB1031

Combined Antiplatelet Therapy Reduces the Pro-inflammatory Properties of Activated Platelets

A.C. Heinzmann1, D.M Coenen1, T. Vajen1, J.M. Cosemans1, R.R Koenen1

Abstract Number: PB1028

Curcumin Inhibits Platelets by Activation of Adenosine A2 Receptor and cAMP/PKA Pathway

N. Rukoyatkina1, N. Al Arawe2, S. Gambaryan1, V. Shpakova1

Abstract Number: PB1023

Discovery of WNT/Planar Cell Polarity Membrane Receptors in Platelets

S.P Comer1,2, N. Alkazemi1,2, D. Hamilton1,2, T. O'Neill3, P. Maguire1,2,4

Abstract Number: OC 10.2

Impairment of Platelet Purinergic Signaling in Sickle Cell Disease

T. Brzoska1, E.V. Menchikova1, T.W. Kaminski1, R. Vats1, E. Tutuncuoglu1, S.P. Tofovic1, E.K. Jackson1, M.T. Gladwin1, P. Sundd1

Abstract Number: PB1024

Integrin αIIbβ3 Regulates Platelet Procoagulant Activity in the Lung

T. Brzoska1, T.W. Kaminski1, R. Vats1, E. Tutuncuoglu1, M.T. Gladwin1, P. Sundd1

Abstract Number: PB1034

Investigation of Core and Shell Platelet Mechanics through P2Y12 Antagonism

M. DeCortin1, S. Diamond1

Abstract Number: OC 10.4

Loss of P2Y1 Receptor Desensitization Does Not Impact in vivo Hemostasis or Thrombosis Despite Increased Platelet Reactivity in vitro

D.S. Paul1, T. Blatt2, S. Murcia2, R.H. Lee1, E.G. Clark1, R.A. Nicholas3, W. Bergmeier1

Abstract Number: OC 37.1

Loss of the Rap-GAP, Rasa3 Leads to Severe Thrombocytopenia Primarily due to αIIbβ3 Integrin-dependent Platelet Clearance in the Spleen

R. Lee1, D. Ghalloussi1, P. Kramer1, J. Kenny1, B. Nieswandt2, W. Bergmeier1

Abstract Number: PB1027

Quantitative Assessment of Heterogeneity of Single Platelet Calcium Responses to Activation

F. Balabin1,2, S. Galkina3, I. Zhizhaikina4, M. Panteleev1,3,2, A. Sveshnikova1,2,4,3

Abstract Number: PB1030

Resveratrol Prevents Platelet Activation by Inhibition of ROS Formation

N. Al Arawe1, V. Shpakova2, N. Rukoyatkina2, S. Gambaryan2,1

Abstract Number: PB1032

Targeted Proteasomal Degradation of Platelet BTK and TEC as a Novel Approach in Thrombosis Prevention

A. Munkacsi1, K. Sledz1, I. Hers1

Abstract Number: OC 37.4

The Intracellular Tail of GPIbα Augments GPVI-mediated Signaling in Mice

A. Constantinescu-Bercu1, Y.A Wang1, K.J Woollard1, P. Mangin2, K. Vanhoorelbeke3, J.T. Crawley1, I.I Salles-Crawley1

Abstract Number: LPB0085

The Predominant Role of Arrestin3 in General GPCR Desensitization in Platelets

P.K. Chaudhary1, S. Kim1, S. Kim1

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