Platelets and Megakaryocytes » Platelet Signaling

Abstract Number: PB1025

A rRle for the JAK/STAT5 Axis in GPVI-mediated Platelet Function

I. Parra Izquierdo¹, A. R. Melrose¹, J. Pang¹, S.H. Vasilipalli¹, S. E. Reistma¹, H.H. Sudhan Lakshmanan¹, M. K. Larson², O. J.T. McCarty¹, J. E. Aslan¹

Abstract Number: PB1026

Acetyl-CoA Carboxylase Inhibition Alters Tubulin Acetylation and Aggregation in Thrombin-stimulated Platelets

M. Octave¹, L. Pirotton¹, A. Ginion¹, V. Robaux¹, S. Lepropre¹, S. Kautbally¹, V. Darley-Usmar², J. Ambroise³, B. Guigas⁴, M. Giera⁴, M. Foretz⁵, L. Bertrand¹, C. Beauloye¹, S. Horman¹

Abstract Number: PB1029

Annexin V Binding Detects Platelet Procoagulant Commitment but Is Not Sensitive to Reductions in the Level of Platelet PS Exposure

S. Millington-Burgess¹, M. Harper¹

Abstract Number: PB1033

Antiplatelet Effect of Nobiletin Is Mediated by Activation of DP1 Receptor

V. Shpakova¹, A. Avdeeva², S. Gambaryan¹, N. Rukoyatkina¹

Abstract Number: LPB0132

Chronic Edible Dosing of Δ9-tetrahydrocannabinol (THC) in Non-human Primates Reduces Systemic Platelet Activity and Function

S.E. Reitsma¹, J. Johnson¹, J. Pang¹, I. Parra-Izquierdo^1,2, H. Hara Sudhan Lakshmanan¹, A.R. Melrose^2,1, M. T. Hinds¹, J.E. Aslan^2,1, O.J. McCarty¹, J.O. Lo³

Abstract Number: PB1031

Combined Antiplatelet Therapy Reduces the Pro-inflammatory Properties of Activated Platelets

A.C. Heinzmann¹, D.M Coenen¹, T. Vajen¹, J.M. Cosemans¹, R.R Koenen¹

Abstract Number: PB1028

Curcumin Inhibits Platelets by Activation of Adenosine A2 Receptor and cAMP/PKA Pathway

N. Rukoyatkina¹, N. Al Arawe², S. Gambaryan¹, V. Shpakova¹

Abstract Number: PB1023

Discovery of WNT/Planar Cell Polarity Membrane Receptors in Platelets

S.P Comer^1,2, N. Alkazemi^1,2, D. Hamilton^1,2, T. O'Neill³, P. Maguire^1,2,4

Abstract Number: OC 10.2

Impairment of Platelet Purinergic Signaling in Sickle Cell Disease

T. Brzoska¹, E.V. Menchikova¹, T.W. Kaminski¹, R. Vats¹, E. Tutuncuoglu¹, S.P. Tofovic¹, E.K. Jackson¹, M.T. Gladwin¹, P. Sundd¹

Abstract Number: PB1024

Integrin αIIbβ3 Regulates Platelet Procoagulant Activity in the Lung

T. Brzoska¹, T.W. Kaminski¹, R. Vats¹, E. Tutuncuoglu¹, M.T. Gladwin¹, P. Sundd¹

Abstract Number: PB1034

Investigation of Core and Shell Platelet Mechanics through P2Y₁₂ Antagonism

M. DeCortin¹, S. Diamond¹

Abstract Number: OC 10.4

Loss of P2Y1 Receptor Desensitization Does Not Impact in vivo Hemostasis or Thrombosis Despite Increased Platelet Reactivity in vitro

D.S. Paul¹, T. Blatt², S. Murcia², R.H. Lee¹, E.G. Clark¹, R.A. Nicholas³, W. Bergmeier¹

Abstract Number: OC 37.1

Loss of the Rap-GAP, Rasa3 Leads to Severe Thrombocytopenia Primarily due to αIIbβ3 Integrin-dependent Platelet Clearance in the Spleen

R. Lee¹, D. Ghalloussi¹, P. Kramer¹, J. Kenny¹, B. Nieswandt², W. Bergmeier¹

Abstract Number: PB1027

Quantitative Assessment of Heterogeneity of Single Platelet Calcium Responses to Activation

F. Balabin^1,2, S. Galkina³, I. Zhizhaikina⁴, M. Panteleev^1,3,2, A. Sveshnikova^1,2,4,3

Abstract Number: PB1030

Resveratrol Prevents Platelet Activation by Inhibition of ROS Formation

N. Al Arawe¹, V. Shpakova², N. Rukoyatkina², S. Gambaryan^2,1

Abstract Number: PB1032

Targeted Proteasomal Degradation of Platelet BTK and TEC as a Novel Approach in Thrombosis Prevention

A. Munkacsi¹, K. Sledz¹, I. Hers¹

Abstract Number: OC 37.4

The Intracellular Tail of GPIbα Augments GPVI-mediated Signaling in Mice

A. Constantinescu-Bercu¹, Y.A Wang¹, K.J Woollard¹, P. Mangin², K. Vanhoorelbeke³, J.T. Crawley¹, I.I Salles-Crawley¹

Abstract Number: LPB0085

The Predominant Role of Arrestin3 in General GPCR Desensitization in Platelets

P.K. Chaudhary¹, S. Kim¹, S. Kim¹