Hemostatic Systems in Cancer, Inflammation and Immunity » Platelets and Cancer

Abstract Number: VPB0759

Cancer-associated fibroblasts promote venous thrombosis through C-type lectin-like receptor 2/podoplanin in 3LL lung cancer mouse model

T. Shirai¹, T. Sasaki², N. Tsukiji², S. Ohishi², R. Yokomori², K. Takano², K. Suzuki-Inoue³

Abstract Number: PB0750

Changes to platelet quality and function in Waldenstrӧm Macroglobulinaemia

S. Brysland¹, D. Talaulikar², E. Gardiner³

Abstract Number: PB0748

Diminished platelet CLEC-2 sensitivity in kaposiform hemangioendothelioma identified with novel CLEC-2 antagonists

A. Martyanov¹, I. Tesakov², O. An¹, A. Ignatova², G. Svidelskaya³, L. Khachatryan³, J. Eble⁴, D. Kalinin⁵, A. Sveshnikova³

Abstract Number: VPB0760

Heightened Procoagulation After Thromboprophylaxis Completion inOrthopaedic Surgery Patients with Metastatic Bone Disease: Outcome of A Pilot Study

E. Agbani¹, L. Yamaura², D. Young², M. Monument², L. Skeith², A. Dufour², P. Schneider²

Abstract Number: VPB0758

JAK2 V617F Confers Aspirin Resistance in Patients with Myeloproliferative Neoplasms

K. Rizzo¹, K. Vella², M. Cini Masini², L. Camilleri³, N. Riva⁴, A. Gatt⁵

Abstract Number: OC 72.3

JAK2V617F mutation exacerbates the thrombo-inflammatory response to Cerebral Venous Sinus Thrombosis in mice

M. BOURRIENNE¹, M. Solo-nomenjanahary², D. Faille³, J. GAY⁴, S. Loyau⁵, J. Villeval⁶, V. Edmond⁶, I. Plo⁶, B. Ho-Tin-Noé⁷, M. Mazighi⁸, N. Ajzenberg⁹

Abstract Number: PB0752

Platelet and immune cell cloaking of circulating tumour cells [CTCs] in breast and ovarian cancer

M. Ward¹, L. Kane², S. Lochrin³, C. Ovaere⁴, C. O’Gorman⁴, R. O'Connor⁵, T. Kelly⁵, B. Mohamed⁵, M. Bates⁵, M. Carter⁵, J. Kennedy³, A. Tierney³, J. Beirne⁶, W. Kamran⁴, F. Abu Saadeh⁷, K. Cadoo⁸, L. Norris⁹, C. Martin¹⁰, S. O'Toole¹¹, J. O'Leary¹²

Abstract Number: PB0753

Platelet count as a novel diagnostic marker for early lung cancer diagnosis: an epidemiological study

M. Barlow¹, G. Pula², W. Hamilton¹, S. Bailey¹

Abstract Number: OC 66.2

Platelet-mediated potentiation of the lung pre-metastatic niche in breast cancer

H. Roweth¹, M. Malloy², Q. Guo³, I. Becker⁴, S. McAllister³, E. Battinelli³

Abstract Number: PB0751

Platelets are integral components of the tumor microenvironment whose regulatory actions vary with the tumor type

O. Le Chapelain¹, S. Jadoui², V. Ollivier², B. Ho-Tin-Noé³

Abstract Number: PO0043

Post-thrombotic hypercoagulation syndrome in patients with hemoblastoses

I. Berger

Abstract Number: PB0756

Proteomic and functional profile of platelet-derived extracellular vesicles released under physiological and tumour-associated conditions

M. Vismara¹, M. Manfredi², M. Zarà³, L. Galgano⁴, S. Trivigno⁴, A. Piotti⁵, I. Canobbio¹, M. Torti⁵, G. Guidetti¹

Abstract Number: VPB0761

Severe hemorrhage complicated with acute multiple cerebral infarction in a patient with thrombocytopenia caused by chemotherapy

R. Zhou, D. Zhou

Abstract Number: PB0749

Significance of platelet count at diagnosis and its association with survival in Myelodysplastic Syndrome patients; an experience from Pakistan

N. Anwar¹, N. Fatima², A. Arshad³, L. Majeed², M. Borhany⁴

Abstract Number: PB0755

Synthetic Bcr-Abl tyrosine kinase inhibitors; their profile towards antiplatelet activity and cancer cell functionality

L. Pechlivani¹, N. Ntemou², P. Boulgari², D. Pantazi¹, K. Skobridis², A. Tselepis¹

Abstract Number: OC 66.3

The Lung Pro-thrombotic Niche Drives Cancer-Associated Thromboembolism via Exosomal ITGB2

S. Lucotti¹, Y. Ogitani², C. Kenific¹, L. Bojmar¹, M. Cioffi¹, P. Lauritzen¹, H. Molina³, S. Heissel³, H. Lengel⁴, X. Jing⁵, H. Zhang¹, I. Matei¹, E. O'Reilly⁴, W. Jarnagin⁴, D. Jones⁴, J. Bussel¹, D. Kelsen⁴, J. Bromberg⁴, D. Simeone⁵, D. Lyden¹

Abstract Number: PB0754

Treatment of hepatocellular carcinoma with autologous platelets encapsulating sorafenib or lenvatinib: a novel therapy exploiting tumor-platelet interactions

H. Tanaka¹, K. Horioka²

Abstract Number: VPB0757

TREGs-induced Immune Thrombotic Thrombocytopenia in Polycythemia Vera

R. Cacciola¹, V. Vecchio², E. Gentilini Cacciola³, E. Cacciola¹