Hemostatic Systems in Cancer, Inflammation and Immunity » Platelets and Inflammation

Abstract Number: PB0777

Adenovirus-based but not mRNA-based vaccines transiently alter platelet count homeostasis in healthy subjects.

L. lombardi¹, N. Scafa², S. Cesaroni¹, R. Marrapodi³, F. Maiorca⁴, R. Cangemi¹, M. Visentini¹, G. Romiti¹, B. Corica¹, F. Pulcinelli³, M. Venneri¹, S. Basili¹, L. Stefanini³

Abstract Number: PB0775

Disruption of the interaction of platelets with leukocytes by a novel short synthetic peptide targeting P-selectin

S. Wallis¹, N. Wolska², M. Posner³, A. Upadhyay⁴, T. Renné⁵, I. Eggleston⁶, S. Bagby¹, G. Pula⁷

Abstract Number: PB0770

High levels of TLT-1+, but not Gp1b+, Microparticles Are Indicative of Poor Outcomes in Acute Respiratory Distress Syndrome

A. Gibson¹, A. Washington², J. Warrick¹

Abstract Number: OC 66.5

Mitochondrial dysfunction in platelets from patients with JAK2 V617F essential thrombocythemia and polycythemia vera underlie thrombo-hemorrhagic complications

O. Esparza¹, B. McMahon², G. Hernandez³, D. Le³, M. Kelher⁴, T. Nemkov⁵, A. D'Alessandro⁵, J. Lopez⁶, P. Davizon-Castillo⁷

Abstract Number: PB0769

Platelet Activation and Expression of CAR on Cardiomyocytes and Platelets: Implication on Inflammation in Patients with Dilated Cardiomyopathy

G. Elena¹, L. Buryachkovsaya¹, N. Mironova¹, P. Chumachenko¹, S. Golitsyn¹, M. Othman²

Abstract Number: OC 72.1

Platelet HMGB1 mediates pathological NET formation in Ischemic Stroke

F. Denorme¹, I. Portier¹, Y. Kosaka¹, J. Rustad¹, M. Cody¹, C. Yost¹, M. Neal², J. Majersik¹, R. Campbell¹

Abstract Number: PB0773

Platelet number and function alterations in preclinical models of sterile inflammation and sepsis patients: implications in the pathophysiology and treatment of inflammation

M. Villa-Fajardo¹, M. Yáñez Palma², A. Acebes-Huerta³, P. Martínez-Botía⁴, M. Meinders⁵, M. Nolte⁶, C. Benavente Cuesta⁷, J. Eble⁸, J. del Castillo², F. Martín-Sánchez², L. Gutiérrez⁹

Abstract Number: VPB0778

Platelet proteomics reveals an inflammatory phenotype of platelets in type 2 diabetes

Y. Kong¹, R. Rehan², J. Weaver³, C. Houlahan⁴, B. Johnston⁴, K. Peng⁴, M. Cielesh⁴, M. Larance⁵, F. Passam⁶

Abstract Number: PB0772

Platelet-Leukocyte Aggregates as Markers of (Pro)Thrombotic Inflammation

A. Peshkova¹, K. Sounbuli², Y. Selivanova², I. Andrianova², R. Litvinov³, J. Weisel⁴

Abstract Number: PB0771

Platelets promote neutrophil extracellular traps mediated thrombo-inflammation and glomerular endothelial dysfunction in diabetic kidney disease

A. Gupta¹, K. Singh¹, R. Younis¹, S. Krishnan², S. Fatima², S. Ambreen², H. Mai², N. Hoffmann², R. Biemann², K. Shahzad², S. Zimmermann², B. Isermann³, S. Kohli³

Abstract Number: LB 02.3

Sirtuin 1 as an endogenous inhibitor of NETosis

L. Wang¹, C. Yuen¹, S. Wong²

Abstract Number: PB0767

The Relevance of Thromboinflammatory Biomarkers and their Relationship with Circulating Glycosaminoglycans in End-Stage Renal Disease Patients

M. Allen¹, V. Bansal², F. Siddiqui², D. Hoppensteadt³, E. Krupa², B. Kantarcioglu⁴, J. Fareed³

Abstract Number: PB0774

The role of platelets in chemotherapy-associated steatohepatitis

P. Spitzenstätter¹, J. Sturm¹, M. Derler¹, D. Pereyra², P. Starlinger³, A. Assinger⁴, M. Mussbacher¹

Abstract Number: PB0768

The role of platelets in ER stress-induced hepatic steatosis

M. Derler¹, W. Schrottmaier², M. Salzmann², G. Schoiswohl¹, J. Schmid³, A. Assinger², M. Mussbacher¹

Abstract Number: OC 72.4

Toxicity of neutrophil extracellular traps (NETs) and the effects of platelet factor 4 (PF4) on NET thrombogenicity: Therapeutic implications

A. Ngo¹, C. Field², A. Sarkar¹, I. Yarovoi¹, G. Zhao¹, L. Rauova¹, M. Kowalska¹, M. Poncz¹, K. Gollomp¹

Abstract Number: PB0776

Using a multi-omics approach to understand endothelial dysregulation of platelet activation in inflammatory conditions

C. Schönichen¹, I. Provenzale², A. Ludt³, F. Solari⁴, F. Marini⁵, A. Cleuren⁶, K. Jurk⁷, M. Stoll⁸, A. Sickmann⁴, M. Kuijpers⁹, J. Heemskerk¹⁰