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ISTH 2021 Congress

Platelets and Megakaryocytes

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  • ISTH 2021 Congress
    • Platelets and Megakaryocytes
      • Megakaryocytes and Thrombopoiesis
      • Platelet Function and Interactions
      • Platelet Proteomics and Genomics
      • Platelet Receptors
      • Platelet Signaling

Abstract Number: PB0984

A comparison of Five Platelet Reactivity Tests in Over 3,000 Participants of the Framingham Heart Study

M.V. Chan1, M.-H. Chen1, F. Thibord1, A. Lachapelle1, J. Grech1, P.C.J. Armstrong2, T.D. Warner2, A.D. Johnson1

Abstract Number: OC 74.2

A Heterozygous Mutation in SLFN14 Influences Species-specific Haematopoietic Regulation in Platelet and Erythroid Lineages

R. Stapley1, C. Smith1, E. Haining1, A. Bacon2, S. Lax3, V. Pisareva4, A. Pisarev4, S. Watson1,5, A. Khan1, N. Morgan1

Abstract Number: LPB0130

A Multiscale Framework for Patient-specific Predictions of Thrombus Growth

K. Shankar1, T. Sinno1, S. Diamond1

Abstract Number: OC 61.3

A Novel Particle-based Model Delivers Mechanistic Insights into Arterial Thrombus Heterogeneity

A.A. Masalceva1,2, V.N. Kaneva1,2,3, M.A. Panteleev1,2,3,4, F.I. Ataullahanov1,2,3,4, V. Volpert5,6,7, I.V. Afanasyev8,9, D.Y. Nechipurenko1,2,3

Abstract Number: PB0971

A Novel Therapeutic Strategy for Hepatocellular Carcinoma Based on the Tumor-platelet Interaction

H. Tanaka1, K. Horioka2

Abstract Number: PB1025

A rRle for the JAK/STAT5 Axis in GPVI-mediated Platelet Function

I. Parra Izquierdo1, A. R. Melrose1, J. Pang1, S.H. Vasilipalli1, S. E. Reistma1, H.H. Sudhan Lakshmanan1, M. K. Larson2, O. J.T. McCarty1, J. E. Aslan1

Abstract Number: PB0954

Aberrant Expression of Lnc-MEG3 and Lnc-NOTCH1 Predicts Refractory Phenotype in Chronic Idiopathic Thrombocytopenic Purpura

N. El-Khazragy1,2, S. Matbouly3, H.F. Abdelsamee4

Abstract Number: PB1026

Acetyl-CoA Carboxylase Inhibition Alters Tubulin Acetylation and Aggregation in Thrombin-stimulated Platelets

M. Octave1, L. Pirotton1, A. Ginion1, V. Robaux1, S. Lepropre1, S. Kautbally1, V. Darley-Usmar2, J. Ambroise3, B. Guigas4, M. Giera4, M. Foretz5, L. Bertrand1, C. Beauloye1, S. Horman1

Abstract Number: OC 11.3

Active Sorting of Platelets and Red Blood Cells in Contracting Blood Clots is Driven by Platelet-generated Forces that Stiffen Fibrin

V. Tutwiler1,2, X. Chen1, R.I. Litvinov1,3, R. Khismatullin1,3, J. Kaufmanova1, C. Nagaswami1, J.W. Weisel1, V.B. Shenoy1

Abstract Number: OC 37.3

Affimers Modulate GPVI Interactions with Collagen/Fibrinogen and GPVI-mediated Platelet Aggregation

R.-G. Xu1, L.T. Cheah1, L. Adams2, C. Tiede2, J.S. Gauer1, A. Slater3, C. Duval1, D. Tomlinson2, K. Naseem1, A.B. Herr4, S.P. Watson3, R.A.S. Ariëns1

Abstract Number: PB0999

An Oxidative Stress-induced Platelet-associated Tissue Factor Expression Characterizes Patients with Migraine and Patent Foramen Ovale

P. Canzano1, D. Trabattoni1, M. Brambilla1, B. Porro1, A. Becchetti1, S. Fiorelli1, E. Tremoli1, M. Camera1,2

Abstract Number: PB1029

Annexin V Binding Detects Platelet Procoagulant Commitment but Is Not Sensitive to Reductions in the Level of Platelet PS Exposure

S. Millington-Burgess1, M. Harper1

Abstract Number: PB0998

Antiplatelet Activity Produced by Chloroacilhidroquinones via Inhibition of the Mitochondrial Bioenergy

E. Fuentes1, D. Méndez1, I. Palomo1, M. Alarcón1, F.A. Urra2, A. Trostchansky3, J.P. Millas-Vargas4, R. Araya-Maturana4

Abstract Number: PB1033

Antiplatelet Effect of Nobiletin Is Mediated by Activation of DP1 Receptor

V. Shpakova1, A. Avdeeva2, S. Gambaryan1, N. Rukoyatkina1

Abstract Number: PB0989

Assessment of the Effects of Syk and BTK Inhibitors on GPVI-mediated Platelet Signaling and Function

T. Zheng1, E. Lofurno2, A. Melrose1, H. Lakshmanan1, J. Pang1, K. Phillips3, M. Fallon1, T. Kohs1, A. Ngo1, J. Shatzel1, M. Hinds1, O. McCarty1, J. Aslan1

Abstract Number: PB0953

Bifunctional Effect of Inflammatory Cytokine TNFα on Human Megakaryopoiesis and Platelet Production

T. Chu1, S. Hu1,2, J. Qi1,2,3,4, Y. Han1,2,3,4, D. Wu1,2,3,4

Abstract Number: PB1005

Case Report: Skin Necrosis in setting of Heparin and Warfarin Exposure

D.Z.S. Eng1, C.P. Coorey1, D. Hsu1, S. Mallik1

Abstract Number: PB1019

Charactering the Role of TLT-1 in Inflammatory Pathogenesis of Obesity and Nonalcoholic Fatty Liver Disease (NAFLD)

S. Branfield1, B. Nieves Lopez2, M. Poynter3, A.V. Washington1

Abstract Number: OC 52.2

Characterization of the Role of Integrin α5β1 in Platelet Function, Haemostasis and Arterial Thrombosis in Mice

E. Janus-Bell1, A. Yakusheva1,2, N. Receveur1, U.M. Ahmed1, C. Mouriaux1, C. Bourdon1, M.A. Panteleev2, C. Gachet1, P.H. Mangin1

Abstract Number: LPB0132

Chronic Edible Dosing of Δ9-tetrahydrocannabinol (THC) in Non-human Primates Reduces Systemic Platelet Activity and Function

S.E. Reitsma1, J. Johnson1, J. Pang1, I. Parra-Izquierdo1,2, H. Hara Sudhan Lakshmanan1, A.R. Melrose2,1, M. T. Hinds1, J.E. Aslan2,1, O.J. McCarty1, J.O. Lo3

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